journal article·2015-08

Instrumental characterization of the smectite clay–gentamicin hybrids

ALICJA RAPACZ-KMITA, EWA STODOLAK-ZYCH, MAGDALENA ZIABKA, AGNIESZKA ROZYCKA, MAGDALENA DUDEK

Bulletin of Materials Science· Volume 38· Issue 4
Publisher page

Abstract

This paper focusses on the intercalation of clay mineral with gentamicin (an aminoglycoside antibiotic). The smectite clay–gentamicin hybrids were prepared by a solution intercalation at 60∘C and the process was carried out on unmodified smectite clay and on smectite after Na+ ionic activation. The resulting structural/microstructural properties and the potential for introducing gentamicin between smectite clay layers were investigated by means of X-ray diffraction, Fourier transform infrared spectroscopic techniques and transmission electron microscopy and scanning electron microscopy with energy-dispersive spectroscopy X-ray analysis. The results confirm the successful intercalation of gentamicin into the interlayer space of smectite clay, demonstrating that the material thus obtained could potentially be used as a drug carrier.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Clay minerals and soil interactions · Therapeutic Uses of Natural Elements · Soil and Unsaturated Flow

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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