Preparation of dual-sensitive graft copolymer hydrogel based on N-maleoyl-chitosan and poly(N-isopropylacrylamide) by electron beam radiation
Source abstract
Abstract
Organic solvent-soluble N-maleoyl-chitosan (NMCS) was synthesized by reaction of chitosan with maleic anhydride (MAH) in N, N-dimethylformamide (DMF). N-maleoyl-chitosan-graft-poly(N-isopropylacrylamide) (NMCS-g-PNIPAAm) copolymer hydrogel was prepared via free radical polymerization by electron beam (EB) irradiation. The copolymer obtained was analysed by FT-IR, XRD and thermal gravimetric analysis (TGA). It was found that the grafting yield and grafting efficiency increased with increasing radiation absorbed dose and monomer amount, and then decreased. The swelling ratio of the copolymer hydrogel was low at pH 4–5, and LCST of the hydrogel was around 32°C.
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Research context
OpenAlex topics: Hydrogels: synthesis, properties, applications · Polymer Nanocomposite Synthesis and Irradiation · Advanced Drug Delivery Systems
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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