journal article·2026-02-10Open access

Development of Green Nano-Fibrillated Fibroin–Sericin Composite Films

Flore Vanessa Mabeya, Yoko Okahisa

Abstract

Regenerated silk fibroin (SF) nanofibers are known for their brittleness, which poses challenges for practical applications. Moreover, the complete removal of sericin (SS) adversely affects the mechanical properties of SF. This study presents an innovative, green, one-step method for extracting nano-fibrillated SF using only water, through a combination of autoclaving and grinding treatments. Silk fibers (SF/SS) were autoclaved for varying durations to retain different amounts of SS and enhance mechanical performance. A series of SF/SS samples with different degumming times was prepared to assess the influence of SS content before and after film formation. A set of fibroin–sericin-based nano-fibrillated (FNF/SS) composite films with improved mechanical properties was developed. Controlled SS content significantly enhanced the mechanical performance of SF.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Silk-based biomaterials and applications · Electrospun Nanofibers in Biomedical Applications · Dyeing and Modifying Textile Fibers

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biobased Materials Science, Graduate School of Science and Technology, Kyoto In-stitute of Technology, Japan

Faculty of Fiber Science and Engineering, Kyoto Institute of Technology, Japan

References (30)

Show source-provided references
1. R. F. P. Pereira, M. M. Silva, and V. De Zea Bermudez, Macromol. Mater. Eng., 300, 1171 (2015).10.1002/mame.201400276 ↗
2. T. T. Cao and Y. Q. Zhang, Mater. Sci. Eng. C, 61, 940 (2016).
3. R. I. Kunz, R. M. C. Brancalhão, L. D. F. C. Ribeiro, and M. R. M. Natali, Biomed. Res. Int., 2016, 8175701 (2016).10.1155/2016/8175701 ↗
4. A. Bucciarelli, G. Greco, I. Corridori, N. M. Pugno, and A. Motta, ACS Biomater. Sci. Eng., 7, 1374 (2021).10.1021/acsbiomaterials.0c01657 ↗
5. H. Y. Wang and Y. Q. Zhang, Sci. Rep., 4, 6182 (2014).
6. M. Shibata and Y. Okahisa, Heliyon, 10, e39101 (2024).10.1016/j.heliyon.2024.e39101 ↗
7. C. Narita, Y. Okahisa, I. Wataoka, and K. Yamada, ACS Omega, 5, 22786 (2020).10.1021/acsomega.0c01750 ↗
8. Y. Okahisa, C. Narita, and K. Yamada, Mater. Today Commun., 25, 101630 (2020).10.1016/j.mtcomm.2020.101630 ↗
9. B. L. Sacco and H. de Santana, Quim. Nova, 42, 1014 (2019).
10. M. Li, W. Tian, Y. Zhang, H. Song, Y. Yu, X. Chen, N. Yong, X. Li, Y. Yin, Q. Fan, and J. Wang, Polymers (Basel)., 14, 2466 (2022).10.3390/polym14122466 ↗
11. M. Li, W. Tian, Y. Yu, Y. Zhang, B. Zhang, J. Xu, and J. Wang, Sci. Rep., 13, 33844 (2023).10.1038/s41598-023-33844-2 ↗
12. J. H. Lee, D. W. Song, Y. H. Park, and I. C. Um, Int. J. Biol. Macromol., 89, 273 (2016).10.1016/j.ijbiomac.2016.04.073 ↗
13. Y. Okahisa, C. Narita, and K. Yamada, J. Fiber Sci. Technol., 75, 29 (2019).10.2115/fiberst.2019-0005 ↗
14. A. Veiga, F. Castro, F. Rocha, and A. L. Oliveira, Front. Mater., 7, 24 (2020).10.3389/fmats.2020.00024 ↗
15. L. Lamboni, M. Gauthier, G. Yang, and Q. Wang, Biotechnol. Adv., 33, 1855 (2015).10.1016/j.biotechadv.2015.10.014 ↗
16. Z. Wang, Y. Zhang, J. Zhang, L. Huang, J. Liu, Y. Li, G. Zhang, S. C. Kundu, and L. Wang, Sci. Rep., 4, 7064 (2014).10.1038/srep07064 ↗
17. B. M. Bakadia, A. Zhong, X. Li, B. O. O. Boni, A. A. Q. Ahmed, T. Souho, R. Zheng, Z. Shi, D. Shi, L. Lamboni, and G. Yang, Adv. Compos. Hybrid Mater., 5, 2847 (2022).10.1007/s42114-022-00467-6 ↗
18. L. Lamboni, Y. Li, J. Liu, and G. Yang, Biomacromolecules, 17, 3076 (2016).10.1021/acs.biomac.6b00995 ↗
19. A. Gaviria, N. Jaramillo-Quiceno, A. Motta, and A. Restrepo-Osorio, Sci. Rep., 13, 41762 (2023).10.1038/s41598-023-41762-6 ↗
20. Y. E. Kim, Y. J. Bae, M. J. Jang, and I. C. Um, Biomolecules, 13, 1186 (2023).10.3390/biom13081186 ↗
21. L. K. H. Rocha, L. I. L. Favaro, A. C. Rios, E. C. Silva, W. F. Silva, T. P. Stigliani, M. Guilger, R. Lima, J. M. Oliveira, N. Aranha, M. Tubino, M. M. D. C. Vila, and V. M. Balcão, Process Biochem., 61, 163 (2017).10.1016/j.procbio.2017.06.019 ↗
22. H. P. Zhao, X. Q. Feng, S. W. Yu, W. Z. Cui, and F. Z. Zou, Polymer (Guildf)., 46, 9192 (2005).10.1016/j.polymer.2005.07.004 ↗
23. J. Saha, M. I. H. Mondal, M. R. Karim Sheikh, and M. A. Habib, J. Text. Sci. Eng., 9, 390 (2019).
24. F. Bi, Y. Chen, J. Liu, W. Hu, and K. Tian, Stem Cells Int., 2021, 6697969 (2021).10.1155/2021/6697969 ↗
25. Y. Okahisa, C. Narita, T. Aoki, Int. J. Biol. Macromol., 191, 1017 (2021).10.1016/j.ijbiomac.2021.09.125 ↗
26. Z. L. Zhao and Y. Q. Zhang, J. Clean. Prod., 261, 121080 (2020).10.1016/j.jclepro.2020.121080 ↗
27. M. Gandhi, H. Yang, L. Shor, and F. Ko, Polymer (Guildf)., 50, 1918 (2009).10.1016/j.polymer.2009.02.022 ↗
28. Y. Tamada, Biomacromolecules, 6, 3100 (2005).10.1021/bm050431f ↗
29. M. Li, M. Ogiso, and N. Minoura, Biomaterials, 24, 357 (2003).10.1016/S0142-9612(02)00326-5 ↗
30. R. Wang, Y. Zhu, Z. Shi, W. Jiang, X. Liu, and Q. Q. Ni, J. Clean. Prod., 203, 492 (2018).10.1016/j.jclepro.2018.08.286 ↗