Use of Nanoparticles in Regenerative Dentistry: A Systematic Review
Source abstract
Abstract
Introduction: nanoparticles are tiny-sized materials whose characteristics and properties mean that their association with dental materials is being investigated to ascertain their effects and possible benefits on tooth structures. This systematic review aimed to qualitatively collect in vitro studies that address the potential application of different nanoparticles in dental regeneration. Following an exhaustive search and article selection process, 16 in vitro studies that met our eligibility criteria were included. BG-NPs were analyzed across five studies, with three demonstrating their impact on the growth and differentiation of human hDPSCs. CS-NPs were examined in three studies, with findings from two indicating a significant effect on the differentiation of SCAPs. Nanoparticles’ therapeutic potential and their stimulatory effect on promoting the regeneration of cells of the dentin-pulp complex have been proven. Their effect is altered according to the type of nanoparticle, concentration, and substances associated with them and, depending on these variables, they will affect the pulp, dentine, and dental cementum differently.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Endodontics and Root Canal Treatments · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Special Care in Dentistry and Gerodontology Unit, Meseguer Hospital, Faculty of Medicine, University of Murcia, 30100 Murcia, Spain
Department of Health Sciences, Catholic Unisersity San Antonio of Murcia, 30107 Murcia, Spain
Funding
Spanish Ministry of Science and Innovation
References (28)
Show source-provided references
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