Effects of Electrospinning Setup and Process Parameters on Nanofiber Morphology Intended for the Modification of Quartz Crystal Microbalance Surfaces

To improve the performance of mass sensitive biosensors, the surface of a piezoelectric quartz crystal transducer, is expanded by employing electrospun nanofibers to its surface. This work describes the effect of vertical - horizontal electrospinning setups and electrospinning parameters on fiber morphology. The research objective was to obtain finer and non-beaded fiber morphologies, via controllable and repeatable process parameters, for further applications of QCM surfaces in high performance DNA-, Aptamer-, Immunosensor applications.