journal article·2027-01

Regulation of epithelial-mesenchymal cell-cell partners by complexes of paracrine signals and sulfated oligosaccharides

Wencheng Zhang, Eliane Wauthier, Yongmei Xu, Guowei Su, Bruce Caterson, Diletta Overi, Guido Carpino, Eugenio Gaudio, Jian Liu, Lola M. Reid

Biomaterials· Volume 336
Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Glycosylation and Glycoproteins Research · Proteoglycans and glycosaminoglycans research · Cancer Cells and Metastasis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. Stem cell‐fueled maturational lineages in hepatic and pancreatic organogenesis
2. Liver cell therapies: cellular sources and grafting strategies10.1007/s11684-023-1002-1 ↗
3. Role of hepatocyte growth regulators in liver regeneration10.3390/cells12020208 ↗
4. The wnt pathway: from signaling mechanisms to synthetic modulators10.1146/annurev-biochem-040320-103615 ↗
5. The R-spondin protein family10.1186/gb-2012-13-3-242 ↗
6. Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury10.1152/ajpgi.00222.2012 ↗
7. Matrix metalloproteinase interactions with collagen and elastin. Review10.1016/j.matbio.2015.01.005 ↗
9. Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes10.1016/j.stemcr.2013.08.006 ↗
10. Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates10.1126/sciadv.abl6026 ↗
11. The tissue factor pathway in cancer: overview and role of heparan sulfate proteoglycans10.3390/cancers15051524 ↗
12. Novel contact-dependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfate Proteoglycans10.1074/jbc.M110.208082 ↗
13. Nuclear translocation of heparan sulfate proteoglycans and their functional significance10.1016/j.bbagen.2014.04.015 ↗
14. Couchman · 2016
15. Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance10.1111/febs.14967 ↗
16. Laminin forms an independent network in basement membranes10.1083/jcb.117.5.1119 ↗
17. Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds10.1002/hep.24012 ↗
18. Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models
19. A systems view of the heparan sulfate interactome10.1369/0022155420988661 ↗
20. Molecular diversity of heparan sulfate10.1172/JCI200113530 ↗
21. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
22. Heparan sulfate Proteoglycans fine-tune Mammalian10.1038/nature05817 ↗
23. Recent innovations in the structural analysis of heparin10.1016/S0167-5273(16)12002-9 ↗
24. Chemoenzymatic synthesis of heparan sulfate and heparin10.1039/C4NP00076E ↗
26. Synthetic heparin10.1016/j.coph.2011.12.002 ↗
27. Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis10.1038/332376a0 ↗
28. Heparan sulphate in the binding and activation of basic fibroblast growth factor10.1093/glycob/2.6.523 ↗
29. Structure and biological interactions of heparin and heparan sulfate10.1016/S0065-2318(01)57017-1 ↗
30. Anticoagulant heparan sulfate: structural specificity and biosynthesis10.1007/s00253-006-0722-x ↗
31. A century of heparin: past, present and future10.1111/jth.13555 ↗
32. Structure and activity of heparin and its fragments: an overview10.1055/s-2007-1002730 ↗
33. Use of biosynthetic enzymes in heparin and heparan sulfate synthesis10.1016/j.bmc.2012.11.053 ↗
34. Synthetic heparin and heparan sulfate: probes in defining biological functions10.1016/j.cbpa.2017.09.012 ↗
35. Chemoenzymatic synthesis of homogeneous heparan sulfate and chondroitin sulfate chimeras10.1021/acschembio.2c00146 ↗
36. Chemoenzymatic design of heparan sulfate oligosaccharides10.1074/jbc.M110.159152 ↗
37. Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides10.1093/glycob/cwu032 ↗
38. Enzymatical placement of 6-O-sulfo groups in heparan sulfate10.1021/bi200072t ↗
39. Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin10.1073/pnas.1117923109 ↗
40. Antithrombin and its role in host defense and inflammation10.3390/ijms22084283 ↗
41. Liver heparan sulfate structure. A novel molecular design10.1016/S0021-9258(19)78112-5 ↗
42. Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate10.1074/jbc.273.1.271 ↗
43. Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin10.1074/jbc.275.7.4599 ↗
44. Heparan sulfate in the nucleus and its control of cellular functions, a mini-review10.1016/j.matbio.2013.10.009 ↗
45. Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: a novel mechanism of tumor-host cross-talk10.1074/jbc.M114.608455 ↗
46. Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity10.1074/jbc.M110.183277 ↗
47. Anticoagulant and signaling functions of antithrombin10.1111/jth.15052 ↗
48. Homogeneous low-molecular-weight heparins with reversible anticoagulant activity10.1038/nchembio.1459 ↗
49. Controlled photochemical depolymerization of K5 heparosan, a bioengineered heparin precursor10.1016/j.carbpol.2011.06.042 ↗
50. Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins10.1126/science.1207478 ↗
51. Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins10.1126/scitranslmed.aan5954 ↗
52. Multi-organ FGF21-FGFR1 signaling in metabolic health and disease10.3389/fcvm.2022.962561 ↗
53. Wnt/β-Catenin signaling in liver development, homeostasis, and pathobiology10.1146/annurev-pathol-020117-044010 ↗
54. Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation10.1126/scisignal.aay9185 ↗
55. Glycosaminoglycan neutralization in coagulation control10.1161/ATVBAHA.118.311102 ↗
56. Solid-phase-supported chemoenzymatic synthesis and analysis of chondroitin sulfate proteoglycan glycopeptides10.1002/anie.202405671 ↗
57. Chemical, molecular, and single-nucleus analysis reveal chondroitin sulfate proteoglycan aberrancy in fibrolamellar carcinoma10.1158/2767-9764.CRC-21-0177 ↗
58. The heparanase/syndecan-1 axis in cancer: mechanisms and therapies10.1111/febs.12168 ↗
59. Biliary tree stem/progenitor cells in glands of extrahepatic and intrahepatic bile ducts: an anatomical in situ study yielding evidence of maturational lineages10.1111/j.1469-7580.2011.01462.x ↗
60. Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential10.1016/j.jhep.2022.08.037 ↗
61. Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets10.1002/hep.24590 ↗
62. A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans10.1038/s41536-023-00303-5 ↗
63. Stem cell populations giving rise to liver, biliary tree and pancreas
64. Stem/progenitor cell niches involved in hepatic and biliary regeneration
65. Evidence for multipotent endodermal stem/progenitor cell populations in human gallbladder10.1016/j.jhep.2014.01.026 ↗
66. The biliary tree--a reservoir of multipotent stem cells10.1038/nrgastro.2012.23 ↗
67. Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates10.1002/hep.23829 ↗
68. Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis10.1002/stem.1460 ↗
69. Progenitor cell niches in the human pancreatic duct system and associated pancreatic duct glands: an anatomical and immunophenotyping study10.1111/joa.12418 ↗
70. Patch grafting, strategies for transplantation of organoids into solid organs such as liver10.1016/j.biomaterials.2021.121067 ↗
71. Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states10.1016/j.biomaterials.2022.121647 ↗
72. Human hepatic stem cells from fetal and postnatal donors10.1084/jem.20061603 ↗
73. Human telomerase activity, telomerase and telomeric template expression in hepatic stem cells and in livers from fetal and postnatal donors10.1097/MEG.0b013e32832973fc ↗
74. Injectable synthetic extracellular matrices for tissue engineering and repair10.1007/978-0-387-34133-0_9 ↗
75. 3-D culture in synthetic extracellular matrices: new tissue models for drug toxicology and cancer drug discovery10.1016/j.advenzreg.2006.12.012 ↗
76. Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery10.1021/ar7000827 ↗
77. Hedgehog signalling in liver pathophysiology10.1016/j.jhep.2017.10.017 ↗
78. Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events10.1152/ajpgi.1999.276.5.G1260 ↗
79. Liver capsules: biliary tree stem cells subpopulations10.1002/hep.28546 ↗
80. The stem cell niche of human livers: symmetry between development and regeneration10.1002/hep.22516 ↗
81. Perivascular mesenchymal progenitors in human fetal and adult liver10.1089/scd.2012.0296 ↗
82. Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigens
83. Identification and characterization of vitamin A-storing cells in fetal liver: implications for functional importance of hepatic stellate cells in liver development and hematopoiesis10.1634/stemcells.2006-0316 ↗
84. Human hepatic stem cell and maturational liver lineage biology10.1002/hep.24157 ↗
85. Hepatic stem cells and hepatoblasts: identification, isolation and Ex Vivo maintenance methods for cell biology
86. Fibrolamellar carcinomas-growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides10.1016/j.matbio.2023.06.008 ↗
87. Hormonally and chemically defined expansion conditions for organoids of biliary tree stem cells
88. Human hepatoblast phenotype maintained by hyaluronan hydrogels10.1002/jbm.b.30717 ↗
89. Chondroitin sulfate enhances the barrier function of basement membrane assembled by heparan sulfate10.1242/dev.200569 ↗
90. Heparan sulfate modulates neutrophil and endothelial function in antibacterial innate immunity10.1128/IAI.00545-15 ↗
91. Order out of chaos: assembly of ligand binding sites in heparan sulfate10.1146/annurev.biochem.71.110601.135458 ↗
92. Heparan sulfate and the roles in assisting viral infections10.1002/med.1026 ↗
93. Significance of heparanase in cancer and inflammation10.1007/s12307-011-0082-7 ↗
94. Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype10.1074/jbc.M111.254789 ↗
95. The cell-surface proteoglycan dally regulates wingless signaling in drosophila10.1038/22336 ↗
96. Heparanase regulates levels of syndecan-1 in the nucleus10.1371/journal.pone.0004947 ↗
97. Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans10.1146/annurev.cb.08.110192.002053 ↗
98. Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids10.1074/jbc.273.19.11563 ↗
99. Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns10.1091/mbc.5.7.797 ↗
100. Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development10.1101/gad.398207 ↗