Incorporation of low-oxidation graphene oxide into electrospun poly(ε-caprolactone) /gelatin scaffolds for human embryonic stem cell‐derived retinal pigment epithelium cell transplantation
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OpenAlex topics: Graphene and Nanomaterials Applications · Pancreatic function and diabetes · Retinal Development and Disorders
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References (60)
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1. The retinal pigment epithelium: functions and roles in ocular diseases10.1016/j.fmre.2023.08.011 ↗
2. Functions and diseases of the retinal pigment epithelium
3. Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration10.1186/s12967-023-03937-7 ↗
4. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis10.1016/S2214-109X(13)70145-1 ↗
5. Retinal pigment epithelium and age‐related macular degeneration: a review of major disease mechanisms10.1111/ceo.13834 ↗
6. Age-related macular degeneration10.1038/s41572-021-00265-2 ↗
7. Prevalence and risk factors of myopic macular degeneration: the Aier-SERI high myopia adult cohort10.1136/bjo-2024-326116 ↗
8. Global prevalence of myopic macular degeneration in general population and patients with high myopia: a systematic review and meta-analysis10.1177/11206721231185816 ↗
9. Retinal cell transplantation in retinitis pigmentosa, Taiwan
10. Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases10.1186/s13287-024-04007-5 ↗
11. Enhancement of retinal pigment epithelial culture characteristics and subretinal space tolerance of scaffolds with 200 nm fiber topography10.1016/j.biomaterials.2013.12.069 ↗
12. Long-term cultivation of retinal pigment epithelium cells on nanofiber scaffolds
13. Osteogenic differentiation of human adipose-derived mesenchymal stem cells in a bisphosphonate-functionalized polycaprolactone/gelatin scaffold10.1016/j.ijbiomac.2023.124573 ↗
14. A novel Bruch's membrane-mimetic electrospun substrate scaffold for human retinal pigment epithelium cells10.1016/j.biomaterials.2014.08.040 ↗
15. Polydopamine-functionalized graphene oxide integrated PCL/gelatin nanofibers for wound infection control10.1016/j.jddst.2025.107379 ↗
16. Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis10.1186/s13287-018-0824-2 ↗
17. Fabrication and characterization of poly (ε-caprolactone)/gelatin nanofibrous scaffolds for retinal tissue engineering10.1080/00914037.2017.1297939 ↗
18. Biomimetic polycaprolactone‐graphene oxide composites for 3D printing bone scaffolds10.1002/mame.202200558 ↗
19. Design of graphene oxide/gelatin electrospun nanocomposite fibers for tissue engineering applications10.1039/C6RA23986B ↗
20. Evaluation of the toxicity of graphene oxide exposure to the eye10.1080/17435390.2016.1210692 ↗
21. Investigating oxidation state-induced toxicity of PEGylated graphene oxide in ocular tissue using gene expression profiles10.1080/17435390.2018.1480813 ↗
22. Functional assessment of cryopreserved clinical grade hESC-RPE cells as a qualified cell source for stem cell therapy of retinal degenerative diseases10.1016/j.exer.2020.108305 ↗
23. Evaluating the cytotoxicity of graphene oxide using embryonic stem cells‐derived cells10.1002/jbm.a.36904 ↗
24. Effects of the surface charge of graphene oxide derivatives on ocular compatibility10.3390/nano12050735 ↗
25. A step by step protocol for subretinal surgery in rabbits
26. Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model10.1186/s13287-021-02395-6 ↗
27. Subretinal delivery of ultrathin rigid-elastic cell carriers using a metallic shooter instrument and biodegradable hydrogel encapsulation10.1167/iovs.11-8260 ↗
28. Nanofiber scaffold-based tissue-engineered retinal pigment epithelium to treat degenerative eye diseases10.1089/jop.2015.0157 ↗
29. Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer10.1167/iovs.12-11239 ↗
30. In vitro investigations on the effects of graphene and graphene oxide on polycaprolactone bone tissue engineering scaffolds10.1007/s42242-024-00280-8 ↗
31. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies10.1016/S0140-6736(14)61376-3 ↗
32. Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients10.1016/j.stemcr.2015.04.005 ↗
33. Subretinal transplantation of embryonic stem cell–derived retinal pigment epithelium for the treatment of macular degeneration: an assessment at 4 years10.1167/iovs.15-18681 ↗
34. Human embryonic stem cell-derived retinal pigment epithelium transplants as a potential treatment for wet age-related macular degeneration10.1038/s41421-018-0053-y ↗
35. Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression10.1074/jbc.M112.354761 ↗
36. The microphthalmia-associated transcription factor (MITF) and its role in the structure and function of the eye10.3390/genes15101258 ↗
37. The blood–retina barrier in health and disease10.1111/febs.16330 ↗
38. Na+/K+-ATPase: more than an electrogenic pump10.3390/ijms25116122 ↗
39. The apical localization of Na+, K+-ATPase in cultured human retinal pigment epithelial cells depends on expression of the β2 subunit10.3389/fphys.2016.00450 ↗
40. Dual roles of graphene oxide to attenuate inflammation and elicit timely polarization of macrophage phenotypes for cardiac repair10.1021/acsnano.7b09107 ↗
41. CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium10.1371/journal.pone.0023148 ↗
42. Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function10.1016/S0002-9440(10)61231-X ↗
43. The role and diagnostic potential of insulin-like growth factor 1 in diabetic retinopathy and diabetic macular edema10.3390/ijms26093961 ↗
44. From insight to eyesight: unveiling the secrets of the insulin-like growth factor axis in retinal health
45. Placental growth factor stabilizes VEGF receptor-2 protein in retinal pigment epithelial cells by downregulating glycogen synthase kinase 3 activity10.1016/j.jbc.2022.102378 ↗
46. Circulating insulin-like growth factor-1: a new clue in the pathogenesis of age-related macular degeneration10.18632/aging.101727 ↗
47. Soy protein nanofiber scaffolds for uniform maturation of human induced pluripotent stem cell-derived retinal pigment epithelium10.1089/ten.tec.2020.0072 ↗
48. Development of kaempferol-loaded gelatin nanoparticles for the treatment of corneal neovascularization in mice10.3390/pharmaceutics11120635 ↗
49. Ultrastrong trapping of VEGF by graphene oxide: anti-angiogenesis application10.1016/j.biomaterials.2016.09.005 ↗
50. Phagocytosis by the retinal pigment epithelium: recognition, resolution, recycling10.3389/fimmu.2020.604205 ↗
51. Single-cell-pore-sized 3D printed scaffolds for retinal pigment epithelial cell therapy
52. Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs10.1126/scitranslmed.aat5580 ↗
53. Graphene family nanomaterials in ocular applications: physicochemical properties and toxicity10.1021/acs.chemrestox.0c00340 ↗
54. Multifunctional scaffolds for biomedical applications: crafting versatile solutions with polycaprolactone enriched by graphene oxide10.1063/5.0184933 ↗
55. Nano-biomaterials for retinal regeneration10.3390/nano11081880 ↗
56. Tissue engineering strategies for ocular regeneration; from bench to the bedside10.1016/j.heliyon.2024.e39398 ↗
57. Human chorioretinal layer thicknesses measured in macula-wide, high-resolution histologic sections10.1167/iovs.10-6377 ↗
58. Morphometric study of bioprinted hydrogel deformation during histological preparation10.1080/01478885.2025.2539624 ↗
59. Targeted drug delivery to the retinal pigment epithelium: untapped therapeutic potential for retinal diseases10.1016/j.drudis.2022.05.024 ↗
60. Advances in nanomedicine-based retinal drug delivery: mechanisms and translational applications10.1186/s12951-025-03848-3 ↗