journal article·2021-05-01Open access

Integrated lignocellulosic biorefinery: Gateway for production of second generation ethanol and value added products

Amisha Patel, Amita R. Shah

Abstract

An increasing demand for energy and depleting petroleum sources has elevated the need for producing alternative renewable resources. Owing to the prominence of lignocellulosic biomass as bio-renewable and the most abundant resource on Earth, this critical review provides perceptions into the potential of lignocellulosic biomass for production of second generation (2G) ethanol and value added products in a biorefinery manner. The efficient utilization of all three components of lignocellulosic biomass (i.e., cellulose, hemicellulose and lignin) would play a significant role in the economic viability of cellulosic ethanol. The pretreatment method is the key to the success of bioconversion processes and greatly influences the economics of biorefinery process. Biotechnology tools and process engineering play pivotal roles in development of integrated processes for production of biofuels, biochemicals and biomaterials from lignocellulosic biomass. Although, lignocellulosic biorefinery has ample scopes, commercial production of biofuels and chemicals is still challenging. In this context, this review entails concept of lignocellulose biorefinery, latest developments in 2G ethanol production process, importance and market potential of 2G ethanol as renewable fuel and value added chemicals, integration of processes, challenges for integrated production of fuel together with value added chemicals and future directions.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Biofuel production and bioconversion · Catalysis for Biomass Conversion · Microbial Metabolic Engineering and Bioproduction

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. Opportunities to overcome the current limitations and challenges for efficient microbial production of optically pure lactic acid10.1016/j.jbiotec.2016.08.008 ↗
2. Lignin conversion: a key to the concept of lignocellulosic biomass-based integrated biorefinery
3. Biorefining: computer aided tools for sustainable design and analysis of bioethanol production10.1016/j.cherd.2009.07.006 ↗
4. Production of xylooligosaccharides and cellulosic ethanol from steam-exploded barley straw10.1515/hf-2018-0101 ↗
5. Polymer grade l-lactic acid production from sugarcane bagasse hemicellulosic hydrolysate using Bacillus coagulans10.1016/j.biteb.2019.02.003 ↗
6. Detoxification of sugarcane-derived hemicellulosic hydrolysate using a lactic acid producing strain10.1016/j.jbiotec.2018.05.006 ↗
7. Pretreatment technologies for an efficient bioethanol production process based on enzymatic hydrolysis: a review10.1016/j.biortech.2009.11.093 ↗
8. From lignocellulosic residues to market: production and commercial potential of xylooligosaccharides10.1016/j.biotechadv.2019.05.003 ↗
9. Continuous production of xylooligosaccharides in a packed bed reactor with immobilized-stabilized biocatalysts of xylanase from Aspergillus versicolor10.1016/j.molcatb.2013.09.017 ↗
10. Evaluating biological pretreatment as a feasible methodology for ethanol production from paddy straw10.1016/j.bcab.2016.08.006 ↗
11. Wet oxidation pretreatment of rape straw for ethanol production10.1016/j.biombioe.2011.12.040 ↗
12. Bioconversion of hemicelluloses of lignocellulosic biomass to ethanol: an attempt to utilize pentose sugars10.1080/17597269.2016.1249738 ↗
13. Liquid fuels, hydrogen and chemicals from lignin: a critical review10.1016/j.rser.2012.12.022 ↗
14. Commercializing lignocellulosic bioethanol: technology bottlenecks and possible remedies10.1002/bbb.188 ↗
15. Xylitol production from lignocellulosic whole slurry corn cob by engineered industrial Saccharomyces cerevisiae PE-210.1016/j.biortech.2018.07.068 ↗
16. Mechanical pretreatments of lignocellulosic biomass: towards facile and environmentally sound technologies for biofuels production10.1039/C4RA07568D ↗
17. Cellulase and oxidative enzymes: new approaches, challenges and perspectives on cellulose degradation for bioethanol production10.1007/s10529-020-02875-4 ↗
18. Biomass, sugar, and bioethanol potential of sweet corn10.1111/gcbb.12136 ↗
19. Bioconversion of plant biomass hydrolysate into bioplastic (polyhydroxyalkanoates) using Ralstonia eutropha 511910.1016/j.biortech.2018.09.122 ↗
20. Insight into progress in pre-treatment of lignocellulosic biomass10.1016/j.energy.2017.01.005 ↗
21. Microwave-assisted acid hydrolysis to produce xylooligosaccharides from sugarcane bagasse hemicelluloses10.1016/j.foodchem.2014.01.112 ↗
22. Wet explosion: a universal and efficient pretreatment process for lignocellulosic biorefineries10.1007/s12155-015-9590-5 ↗
23. An integrated process for xylooligosaccharide and bioethanol production from corncob10.1016/j.biortech.2018.02.004 ↗
24. Deconstruction of lignocellulosic biomass with ionic liquids10.1039/c2gc36364j ↗
25. Optimization of corn stover biorefinery for coproduction of oligomers and second generation bioethanol using non-isothermal autohydrolysis10.1016/j.indcrop.2014.01.003 ↗
26. THF co-solvent enhances hydrocarbon fuel precursor yields from lignocellulosic biomass10.1039/c3gc41214h ↗
27. Xylo-oligosaccharides from lignocellulosic materials: chemical structure, health benefits and production by chemical and enzymatic hydrolysis10.1016/j.foodres.2012.11.021 ↗
28. Relevance of the acidic 1-butyl-3-methylimidazolium hydrogen sulphate ionic liquid in the selective catalysis of the biomass hemicellulose fraction10.1039/C5RA07159C ↗
29. Yeast for pentose fermentation: isolation, screening, performance, manipulation, and prospects
30. Designing cellulolytic enzyme systems for biorefinery: from nature to application10.1016/j.jbiosc.2019.05.007 ↗
31. The path forward for lignocellulose biorefineries: bottlenecks, solutions, and perspective on commercialization10.1016/j.biortech.2018.06.004 ↗
32. Key drivers influencing the commercialization of ethanol-based biorefineries10.1057/jcb.2010.5 ↗
33. Characterization of purified fungal endoxylanase and its application for production of value added food ingredient from agroresidues10.1016/j.fbp.2013.08.005 ↗
34. Production of xylooligosaccharides from corncob xylan by fungal xylanase and their utilization by probiotics10.1016/j.biortech.2011.10.083 ↗
35. Industrial technologies for bioethanol production from lignocellulosic biomass10.1016/j.rser.2015.12.069 ↗
36. Genetic improvement of Saccharomyces cerevisiae for xylose fermentation10.1016/j.biotechadv.2007.04.001 ↗
37. Lignocellulolytic enzymes in biotechnological and industrial processes: a review10.3390/su12187282 ↗
38. Dietary intake of xylooligosaccharides improves the intestinal microbiota, fecal moisture, and pH value in the elderly10.1016/j.nutres.2007.09.014 ↗
39. The biorefinery concept-an integrated approach
40. Green chemistry, biofuels, and biorefinery10.1146/annurev-chembioeng-062011-081014 ↗
41. Improvement on d-xylose to xylitol biotransformation by Candida guilliermondii using cells permeabilized with triton X-100 and selected process conditions10.1007/s12010-016-2146-0 ↗
42. A novel expression system for lytic polysaccharide monooxygenases10.1016/j.carres.2017.02.003 ↗
43. Lactobacillus pentosus CECT 4023 T co-utilizes glucose and xylose to produce lactic acid from wheat straw hydrolysate: anaerobiosis as a key factor10.1002/btpr.2739 ↗
44. ‘Cradle-to-grave’ assessment of existing lignocellulose pretreatment technologies10.1016/j.copbio.2009.05.003 ↗
45. Xylooligosaccharides production by fungi cultivations in rice husk and their application as substrate for lactic acid bacteria growth10.1016/j.biteb.2018.05.004 ↗
46. Xylitol production from lignocellulosic pentosans: a rational strain engineering approach toward a multiproduct biorefinery10.1021/acs.jafc.8b05509 ↗
47. Producing PHAs in the bioeconomy—Towards a sustainable bioplastic10.1016/j.spc.2016.09.001 ↗
48. Effect of various pretreatment methods on bioethanol production from cotton stalks10.3390/fermentation5010005 ↗
49. Dupont Accellerase®, 2019. Cellulase enzyme complex for lignocellulosic biomass hydrolysis. Available at: http://www.accellerase.dupont.com. Accessed 1 July 2019.
50. Vanillin production from lignin and its use as a renewable chemical10.1021/acssuschemeng.5b01344 ↗
51. Production of prebiotic xylooligosaccharides from alkaline extracted wheat straw using the K80R-variant of a thermostable alkali-tolerant xylanase10.1016/j.fbp.2014.11.004 ↗
52. Biorefineries: current status, challenges, and future direction10.1021/ef060097w ↗
53. Xylooligosaccharide increases bifidobacteria but not lactobacilli in human gut microbiota10.1039/c3fo60348b ↗
54. Lactic acid production from wheat straw hemicellulose hydrolysate by Lactobacillus pentosus and Lactobacillus brevis10.1016/S0960-8524(01)00135-3 ↗
55. Fuels and chemicals from lignocellulosic biomass: an integrated biorefinery approach10.1021/acs.energyfuels.5b00144 ↗
56. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics10.1093/jn/125.6.1401 ↗
57. 2015
58. 2017
59. 2017
60. 2019
61. 2019
62. Ethanol-water organosolv delignification of liquid hot water (LHW) pretreated sugarcane bagasse enhanced by high-pressure carbon dioxide (HP-CO2)10.1016/j.indcrop.2016.10.003 ↗
63. Design of highly efficient cellulase mixtures for enzymatic hydrolysis of cellulose10.1002/bit.21329 ↗
64. Wet disk milling pretreatment without sulfuric acid for enzymatic hydrolysis of rice straw10.1016/j.biortech.2008.12.057 ↗
65. The effect of prehydrolysis and improved mixing on high-solids batch simultaneous saccharification and fermentation of spruce to ethanol10.1016/j.procbio.2012.12.020 ↗
66. Xylooligosaccharides and fructooligosaccharides affect the intestinal microbiota and precancerous colonic lesion development in rats10.1093/jn/134.6.1523 ↗
67. Xylitol production from lignocellulosics: are corn biomass residues good candidates?10.1016/j.bcab.2017.07.010 ↗
68. Lignocellulosic biomass: a sustainable platform for the production of bio-based chemicals and polymers10.1039/C5PY00263J ↗
69. Xylooligosaccharides production by crude microbial enzymes from agricultural waste without prior treatment and their potential application as nutraceuticals10.1016/j.biortech.2017.08.174 ↗
70. Xylooligosaccharides: an economical prebiotic from agroresidues and their health benefits
71. Effect of sodium sulfite on acid pretreatment of wheat straw with respect to its final conversion to ethanol10.1016/j.biombioe.2016.08.022 ↗
72. Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae10.1016/j.ymben.2003.11.006 ↗
73. Pretreatment of lignocellulose: formation of inhibitory by-products and strategies for minimizing their effects10.1016/j.biortech.2015.10.009 ↗
74. The virtual sugarcane biorefinery—A simulation tool to support public policies formulation in bioenergy10.1089/ind.2015.0015 ↗
75. Principles of biorefineries10.1007/s00253-003-1537-7 ↗
76. Bioethanol, biohydrogen and biogas production from wheat straw in a biorefinery concept10.1016/j.biortech.2008.11.011 ↗
77. Importance of P-series fuels for flexible-fuel vehicles (FFVs) and alternative fuels10.1080/00908310600718841 ↗
78. Sequential high gravity ethanol fermentation and anaerobic digestion of steam explosion and organosolv pretreated corn stover10.1016/j.biortech.2017.08.112 ↗
79. Composition of sugar cane, energy cane, and sweet Sorghum suitable for ethanol production at Louisiana sugar Mills10.1007/s10295-010-0812-8 ↗
80. Kiso · 2005
81. Lignocellulosic biomass processing: a perspective
82. Integrated xylitol production by fermentation of hardwood wastes10.1002/jctb.1828 ↗
83. Recent advances and challenges towards sustainable polyhydroxyalkanoate (PHA) production10.3390/bioengineering4020055 ↗
84. Kreith · 2013
85. Integrated production of cellulosic bioethanol and succinic acid from rapeseed straw after dilute-acid pretreatment10.1016/j.biortech.2018.05.099 ↗
86. Integrated production of cellulosic bioethanol and succinic acid from industrial hemp in a biorefinery concept10.1016/j.biortech.2015.10.081 ↗
87. Current perspective on pretreatment technologies using lignocellulosic biomass: an emerging biorefinery concept10.1016/j.fuproc.2019.106244 ↗
88. Generation of xylooligosaccharides from microwave irradiated agroresidues using recombinant thermo-alkali-stable endoxylanase of the polyextremophilic bacterium Bacillus halodurans expressed in Pichia pastoris10.1016/j.biortech.2014.12.049 ↗
89. Acid hydrolysis of sugarcane bagasse for lactic acid production10.1016/j.biortech.2009.08.091 ↗
90. Ozonolysis pretreatment of maize stover: the interactive effect of sample particle size and moisture on ozonolysis process10.1016/j.biortech.2015.01.042 ↗
91. Availability of four energy crops assessing by the enzymatic hydrolysis and structural features of lignin before and after hydrothermal treatment10.1016/j.enconman.2017.10.089 ↗
92. Improving enzymatic hydrolysis of wheat straw using ionic liquid 1-ethyl-3-methyl imidazolium diethyl phosphate pretreatment10.1016/j.biortech.2009.02.040 ↗
93. Lignocellulosic biomass for bioethanol production: current perspectives, potential issues and future prospects10.1016/j.pecs.2012.03.002 ↗
94. Lin · 2014
95. Cellulosic ethanol production: progress, challenges and strategies for solutions10.1016/j.biotechadv.2019.03.002 ↗
96. Biochemical characterization of a novel xylanase from Paenibacillus barengoltzii and its application in xylooligosaccharides production from corncobs10.1016/j.foodchem.2018.05.023 ↗
97. Consolidated bio-saccharification: leading lignocellulose bioconversion into the real world10.1016/j.biotechadv.2020.107535 ↗
98. Pretreatment of corn straw using the alkaline solution of ionic liquids10.1016/j.biortech.2018.03.117 ↗
99. An update on enzymatic cocktails for lignocellulose breakdown10.1111/jam.13923 ↗
100. Polyhydroxyalkanoate biosynthesis and simultaneous remotion of organic inhibitors from sugarcane bagasse hydrolysate by Burkholderia sp10.1007/s10295-014-1485-5 ↗