Integration of biopolymers in polyacrylic acid hydrogels: Innovations and applications in bioresources and bioproducts
Source abstract
Abstract
The development of sustainable biomaterials has recently attracted great interest in the fields of flexible electronics and biosensing hydrogels. Hydrogels are a class of three-dimensional spatial network structure, and their structure and shape can exhibit reversible or noticeable responses to various stimuli, making them a popular choice for flexible electronic materials in recent years. Acrylic hydrogels, which possess a rich carboxylate network, can provide significant sensing and actuation properties to the hydrogels. They are often synthesized through the co-polymerization of their monomers and cross-linking agents, and they can be combined with naturally occurring biopolymers such as cellulose and chitosan to enhance biocompatibility. In this paper, we review the compounding methods and preparation process technologies of functionalized acrylic hydrogels and the application of polyacrylic acid (PAA) bioproducts in various fields. Finally, we review the current challenges and future directions for acrylic hydrogel prepared sensors and their applications.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Hydrogels: synthesis, properties, applications · Electrospun Nanofibers in Biomedical Applications · biodegradable polymer synthesis and properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Thermal and mechanical properties of graphene oxide nanocomposite hydrogel based on poly(acrylic acid) grafted onto amylose10.1016/j.polymdegradstab.2017.11.022 ↗
2. Versatility of hydrogels: from synthetic strategies, classification, and properties to biomedical applications10.3390/gels8030167 ↗
3. Development of mussel mimetic gelatin based adhesive hydrogel for wet surfaces with self-healing and reversible properties10.1016/j.ijbiomac.2022.12.151 ↗
4. Hydrogel: preparation, characterization, and applications: a review10.1016/j.jare.2013.07.006 ↗
5. A review of actuation and sensing mechanisms in MEMS-based sensor devices10.1186/s11671-021-03481-7 ↗
6. Advances and applications of nanophotonic biosensors10.1038/s41565-021-01045-5 ↗
7. Design and development of trivalent aluminum ions induced self-healing polyacrylic acid novel hydrogels10.1016/j.polymer.2017.08.045 ↗
8. Nanostructured surface functionalization of polyacrylamide hydrogels below the length scale of hydrogel heterogeneity10.1021/acsami.2c12034 ↗
9. Recent trends in the fabrication of starch nanofibers: electrospinning and non-electrospinning routes and their applications in biotechnology10.1007/s12010-018-2797-0 ↗
10. A label-free, sensitive, real-time, semiquantitative electrochemical measurement method for DNA polymerase amplification (ePCR)10.1021/acs.analchem.5b00079 ↗
11. A room-temperature NO2 gas sensor based on CuO nanoflakes modified with rGO nanosheets10.1016/j.snb.2021.129783 ↗
12. Fundamental concepts of hydrogels: synthesis, properties, and their applications10.3390/polym12112702 ↗
13. Diagnosis and management of orthopedic implant-associated infection: a comprehensive review of the literature
14. Synthesis of methotrexate-loaded tantalum pentoxide-poly(acrylic acid) nanoparticles for controlled drug release applications10.1016/j.jcis.2018.11.097 ↗
15. Shiga toxin-producing Escherichia coli infections associated with romaine lettuce-United States, 201810.1093/cid/ciz1182 ↗
16. Internet of Things (IoT) and agricultural unmanned aerial vehicles (UAVs) in smart farming: a comprehensive review10.1016/j.iot.2020.100187 ↗
17. Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow10.1038/s41551-018-0336-5 ↗
18. Rapid safety and quality control during fish shelf-life by using a portable device10.1002/jsfa.10646 ↗
19. New hydrophilic material based on hydrogel polymer for the selective enrichment of intact glycopeptides from serum protein digests10.1016/j.aca.2023.340862 ↗
20. Preparation of partially neutralized poly(acrylic acid) microspheres via inverse Pickering suspension polymerization10.1002/pen.24883 ↗
21. Mechanically reinforced and injectable universal adhesive based on a PEI-PAA/alg dual-network hydrogel designed by topological entanglement and catechol chemistry10.1021/acsami.3c14743 ↗
22. Hydrogel with ultrafast self-healing property both in air and underwater10.1021/acsami.7b17118 ↗
23. Characteristic fingerprints and volatile flavor compound variations in Liuyang Douchi during fermentation via HS-GC-IMS and HS-SPME-GC-MS10.1016/j.foodchem.2021.130055 ↗
24. Sprayable hydrogel dressing accelerates wound healing with combined reactive oxygen species-scavenging and antibacterial abilities10.1016/j.actbio.2021.02.002 ↗
25. Eco-friendly method for preparation of cross-linked PVA/PAA thin films and membranes thereof for water treatment. Iran
26. High sensitivity optical fiber pH sensor using poly(acrylic acid) nanofibers. EN 2013
27. Solution of population balance equations by logarithmic shape preserving interpolation on finite elements10.1016/j.compchemeng.2018.08.008 ↗
28. Comparative adhesion of chemically and physically crosslinked poly(acrylic acid)-based hydrogels to soft tissues10.1016/j.eurpolymj.2020.110250 ↗
29. Identification of a hybrid atypical enteropathogenic and enteroaggregative Escherichia coli (aEPEC/EAEC) clone of serotype O3: H2 associated with a diarrheal outbreak in Brazil10.1007/s42770-021-00580-6 ↗
30. Recent developments in electrochemical detection of illicit drugs in diverse matrices10.1016/j.bios.2020.112579 ↗
31. In-vitro release study of Pt (II) and Fe (III) metallocefotaxime drug candidates in pH dependent releasing mediums mimicking human biological fluids
32. Miniaturized force-compensated hydrogel-based pH sensors10.1016/j.snb.2017.09.183 ↗
33. Electrochemical detection of heavy metal ions in water10.1039/D1CC00983D ↗
34. Hydrogel tissue bioengineered scaffolds in bone repair: a review10.3390/molecules28207039 ↗
35. Cu (OH)2 nanowires/graphene oxide composites based QCM humidity sensor with fast-response for real-time respiration monitoring10.1016/j.snb.2019.127313 ↗
36. Bienzymatic creatine biosensor based on reflectance measurement for real-time monitoring of fish freshness10.1016/j.snb.2018.04.141 ↗
37. Source analysis and source-oriented risk assessment of heavy metal pollution in agricultural soils of different cultivated land qualities10.1016/j.jclepro.2022.130942 ↗
38. A multifunctional hydrogel polyelectrolyte based flexible and wearable supercapacitor10.1016/j.jpowsour.2020.229100 ↗
39. Electrospun membranes for membrane distillation: The state of play and recent advances10.1016/j.desal.2021.115511 ↗
40. Tuning stimuli-responsive properties of alginate hydrogels through layer-by-layer functionalization for dual-responsive dual drug release10.1016/j.colsurfa.2023.132213 ↗
41. A highly stretchable, ultra-tough, remarkably tolerant, and robust self-healing glycerol-hydrogel for a dual-responsive soft actuator10.1039/C9TA10183G ↗
42. Investigation of swelling behavior and mechanical properties of a pH-sensitive superporous hydrogel composite
43. Ultrastretchable, adhesive, fast self-healable, and three-dimensional printable photoluminescent ionic skin based on hybrid network ionogels10.1021/acsami.1c21325 ↗
44. Stretchable, biocompatible, and multifunctional silk fibroin-based hydrogels toward wearable strain/pressure sensors and triboelectric nanogenerators10.1021/acsami.9b19721 ↗
45. Guidable thermophoretic Janus micromotors containing gold nanocolorifiers for infrared laser assisted tissue welding10.1002/advs.201600206 ↗
46. Poly(acrylamide-co-acrylic acid)/chitosan semi-interpenetrating hydrogel for pressure sensor and controlled drug release10.1002/pat.5317 ↗
47. Surface modification of multiwalled carbon nanotubes via surface RAFT copolymerization method and capecitabine-loaded anticancer hydrogel for controlled drug delivery in stomach
48. Hydrogel-based flexible electronics
49. Stimuli-responsive electrospun fibers and their applications10.1039/c0cs00181c ↗
50. pH-responsive circular bilayer biosensor based on the actuation of an interpenetrating polymer network comprising crosslinked nematic liquid crystals and poly(Acrylic Acid)10.1016/j.snb.2022.133096 ↗
51. Synthesis of cross-linked, partially neutralized poly(acrylic acid) by suspension polymerization in supercritical carbon dioxide10.1021/ie3014007 ↗
52. Recent progress of layer-by-layer assembly, free-standing film and hydrogel based on polyelectrolytes10.1002/mabi.202100117 ↗
53. Backbone degradable poly(acrylic acid) analogue via radical ring-opening copolymerization and enhanced biodegradability10.1016/j.chemosphere.2021.133487 ↗
54. Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management10.3390/pharmaceutics13030357 ↗
55. Skin inspired thermoresponsive polymer for constructing self-cooling system10.1016/j.enconman.2022.115251 ↗
56. Removed heavy metal ions from wastewater reuse for chemiluminescence: successive application of lignin-based composite hydrogels10.1016/j.jhazmat.2021.126722 ↗
57. Highly viscoelastic, stretchable, conductive, and self-healing strain sensors based on cellulose nanofiber-reinforced polyacrylic acid hydrogel10.1007/s10570-021-03782-1 ↗
58. Dynamic covalent chemistry approaches toward macrocycles, molecular cages, and polymers10.1021/ar500037v ↗
59. Hydrogels as scaffolds in bone-related tissue engineering and regeneration10.1002/mabi.202300152 ↗
60. Heavy metal contamination status in Greek surface waters: a review with application and evaluation of pollution indices10.1016/j.chemosphere.2020.128192 ↗
61. A review on hydrogels classification and recent developments in biomedical applications10.1080/00914037.2022.2075872 ↗
62. Diagnosis and treatment of hip and knee osteoarthritis: a review10.1001/jama.2020.22171 ↗
63. Recent advancements in optical biosensors for cancer detection10.1016/j.bios.2021.113805 ↗
64. Conducting electrospun fibres with polyanionic grafts as highly selective, label-free, electrochemical biosensor with a low detection limit for non-Hodgkin lymphoma gene10.1016/j.bios.2017.09.042 ↗
65. Sensors for volatile organic compounds10.1021/acsnano.1c10827 ↗
66. Low-voltage reversible electroadhesion of ionoelastomer junctions
67. High-sensitive and stable photonic crystal sensors for visual detection and discrimination of volatile aromatic hydrocarbon vapors10.1016/j.cej.2019.121987 ↗
68. Soft and tough microcapsules with double-network hydrogel shells10.1002/adfm.202203761 ↗
69. Ultrasonography-guided arthrocentesis versus conventional arthrocentesis in treating internal derangement of temporomandibular joint: a systematic review10.1007/s00784-020-03408-z ↗
70. Rapid preparation of N-CNTs/P (AA- co-AM) composite hydrogel via frontal polymerization and its mechanical and conductive properties10.1039/D2RA02003C ↗
71. Completely aqueous processable stimulus responsive organic room temperature phosphorescence materials with tunable afterglow color10.1038/s41467-022-28011-6 ↗
72. Preparation of novel nano-sized hydrogel microcapsules via layer-by-layer assembly as delivery vehicles for drugs onto hygiene paper10.3390/polym10030335 ↗
73. Novel mussel-inspired injectable self-healing hydrogel with anti-biofouling property10.1002/adma.201405166 ↗
74. A pH-sensitive and sustained-release oral drug delivery system: the synthesis, characterization, adsorption and release of the xanthan gum- graft-poly(acrylic acid)/GO-DCFP composite hydrogel10.1039/D1RA01012C ↗
75. Facile access to guar gum based supramolecular hydrogels with rapid self-healing ability and multistimuli responsive gel-Sol transitions10.1021/acs.jafc.8b05130 ↗
76. Polyelectrolyte complex-based self-healing, fatigue-resistant and anti-freezing hydrogels as highly sensitive ionic skins10.1039/C9TA13213A ↗
77. Environmentally stable, mechanically flexible, self-adhesive, and electrically conductive Ti3C2TX MXene hydrogels for wide-temperature strain sensing10.1016/j.nanoen.2021.106502 ↗
78. Hybrid dual crosslinked polyacrylic acid hydrogels with ultrahigh mechanical strength, toughness and self-healing properties via soaking salt solution10.1016/j.polymer.2017.05.070 ↗
79. Functional hydrogels as wound dressing to enhance wound healing10.1021/acsnano.1c04206 ↗
80. Conductive MXene nanocomposite organohydrogel for flexible, healable, low-temperature tolerant strain sensors10.1002/adfm.201904507 ↗
81. Highly sensitive and robust polysaccharide-based composite hydrogel sensor integrated with underwater repeatable self-adhesion and rapid self-healing for human motion detection10.1021/acsami.2c01785 ↗
82. Layer-by-layer assembly of two-dimensional materials: meticulous control on the nanoscale10.1016/j.matt.2020.03.012 ↗
83. Freezing-tolerant, highly sensitive strain and pressure sensors assembled from ionic conductive hydrogels with dynamic cross-links10.1021/acsami.0c06067 ↗
84. Recent progress in PNIPAM-based multi-responsive actuators: a mini-review
85. Functional hydrogel coatings10.1093/nsr/nwaa254 ↗
86. RAFT controlled synthesis of graphene/polymer hydrogel with enhanced mechanical property for pH-controlled drug release10.1016/j.eurpolymj.2013.10.015 ↗
87. Facile room-temperature synthesis of a spherical mesoporous covalent organic framework for ultrasensitive solid-phase microextraction of phenols prior to gas chromatography-tandem mass spectrometry10.1016/j.cej.2019.03.148 ↗
88. High-porosity foam-based iontronic pressure sensor with superhigh sensitivity of 9280 kPa-1
89. Semi-coke-enhanced eco-friendly superabsorbent composites for agricultural application10.1007/s00289-022-04099-0 ↗
90. Improved biotribological properties of polyetheretherketone composites for artificial joints with a ‘soft-on-hard’ structure and brushlike molecules10.1016/j.triboint.2020.106165 ↗
91. Fiber-optic sensors based on Vernier effect10.1016/j.measurement.2020.108451 ↗
92. Case-management protocol for bloody diarrhea as a model to reduce the clinical impact of Shiga toxin-producing Escherichia coli infections. Experience from Southern Italy10.1007/s10096-019-03755-0 ↗
93. Self-defensive antibacterial layer-by-layer hydrogel coatings with pH-triggered hydrophobicity10.1016/j.biomaterials.2014.12.048 ↗
94. Three-fingers FBG tactile sensing system based on squeeze-and-excitation LSTM for object classification10.1109/TIM.2022.3181290 ↗
95. Highly stretchable, self-healing, and strain-sensitive based on double-crosslinked nanocomposite hydrogel10.1016/j.coco.2019.10.007 ↗
96. Shape memory materials and 4D printing in pharmaceutics10.1016/j.addr.2021.03.013 ↗
97. Wearable pressure sensors for pulse wave monitoring
98. Electrochemistry-induced improvements of mechanical strength, self-healing, and interfacial adhesion of hydrogels10.1002/adma.202102308 ↗
99. Wearable electrochemical biosensors in North America10.1016/j.bios.2020.112750 ↗
100. Preparation of poly(acrylic acid) particles by dispersion polymerization in an ionic liquid10.1021/la904115s ↗