journal article·2015-12

Influence of Doping Ions on the Antibacterial Activity of Biomimetic Coating on CoCrMo Alloy

Georgeta Totea, Daniela Ionita, Ioana Demetrescu

Journal of Bionic Engineering· Volume 12· Issue 4
Publisher page

Abstract

In this study biomimetic fluoridated phosphate doped hydrophilic coatings with various ions on CoCrMo alloy were prepared by electrodeposition. Cu and Zn ions were chosen for doping because of their well known antibacterial activity. The structures of the coatings were identified using Fourier-transform Infrared (FTIR) analysis. X-ray Diffraction (XRD) analysis was performed to evaluate crystallite dimensions of the specimen surface. The contact angle was measured in order to establish the hydrophilic/hydrophobic balance and to compute surface energy. All studied samples have a hydrophilic character which is weaken after doping. The time evolution of ions releasing from the coatings was evaluated with an inductively plasma mass spectrometer after immersion in saline phosphate. The hemolytic experiments indicate that except the fluoridated coatings doped with Zn which is slightly hemolytic, all other samples are non hemolytic. The test for antibacterial activity for Staphylococcus aureus and Pseudomonas aeruginosa indicated that the fluoridated biomimetic coating doped with various positive ions increases bacterial growth inhibition level significantly. Fluoridated phosphate coating doped with Cu has best antibacterial activity.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · Corrosion Behavior and Inhibition · Electrochemical Analysis and Applications

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