Intercrossed Microstructures of Hydroxyapatite Sheets of Tibia Bone
Source abstract
Abstract
The observation of Scanning Electron Microscope (SEM) shows that a tibia bone is a kind of bioceramic composite consisting of hydroxyapatite layers and collagen protein matrix. All the hydroxyapatite layers are parallel with the surface of the bone and consist of numerous hydroxyapatite sheets. The observation also shows that there is a kind of intercrossed microstructure of the hydroxyapatite sheets. In this kind of microstructure, the hydroxyapatite sheets in an arbitrary hydroxyapatite layer make a large intercrossed angle with the hydroxyapatite sheets in their adjacent hydroxyapatite layers. The maximum pullout force of the intercrossed microstructure, which is closely related to the fracture toughness of the bone, is investigated and compared with that of the parallel microstructure of the sheets through their representative models. The result of the investigation indicates that the maximum pullout force of the intercrossed microstructure is markedly larger than that of the parallel microstructure, which is experimentally verified.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Bone health and osteoporosis research · Orthopaedic implants and arthroplasty
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (16)
Show source-provided references
1. Vincent J F V. Ceramics from invertebrate animals. In: Levy M, Bass H, Stern R (eds). Handbook of Elastic Properties of Solids, Liquids and Gases, vol. 3, Academic Press, Burlington, USA, 2000.10.1016/B978-012445760-7/50060-5 ↗
2. Currey J D. The many adaptations of bone. Journal of Biomechanics, 2003, 36, 1487–1495.10.1016/S0021-9290(03)00124-6 ↗
3. Weber M, Schoerl T, Roschger P, Klaushofer K, Fratzl P. Relating local bone stiffness and calcium confined nanoin dentation and backscattered electron imaging. MRS Proceeding: Structure and Mechanical Behavior of Biological Materials, 2005, 847, 79–84.
4. Glimcher M J. The nature of the mineral component of bone and the mechanisms of calcification. Instrument Course Lectures, 1987, 36, 49–69.
5. Su X, Sun K, Cui F Z, Landis W J. Organization of apatite crystals in human woven bone. Bone, 2003, 32, 150–162.10.1016/S8756-3282(02)00945-6 ↗
6. Fratzl P, Groschner M, Vogl G, Plenk H, Eschberger J, Fratzl-Zelman N, Koller K, Klaushofer K. Mineral crystals in calcified tissues-A comparative study by SAXS. Journal of Bone and Mineral Research, 1992, 7, 329–334.10.1002/jbmr.5650070313 ↗
7. Lees S, Prostak K. The locus of mineral crystallites in bone. Connective Tissue Research, 1988, 18, 41–54.10.3109/03008208809019071 ↗
8. Taylor D. Fracture and repair of bone: A multiscale problem. Journal of Materials Science, 2007, 42, 8911–8918.10.1007/s10853-007-1698-3 ↗
9. Hazenberg J G, Taylor D, Lee T C. The role of osteocytes and bone microstructure in preventing osteoporotic fractures. Osteoporos International, 2007, 18, 1–8.10.1007/s00198-006-0222-y ↗
10. Deligianmi D D, Apostolopoulos C A. Multilevel finite element modeling for the prediction of local cellular deformation in bone. Biomechanics and Modeling in Mechanobiology, 2008, 7, 151–159.10.1007/s10237-007-0082-1 ↗
11. Fratzl P, Gupta H S, Paschalis E P, Roschger P. Structure and mechanical quality of the collagen-mineral nano-composite in bone. Journal of Materials Chemistry, 2004, 14, 2115–2123.10.1039/B402005G ↗
12. Woesz A, Rumpler M, Stampfl J, Varga F, Fratzl,, Roschger Z N, Klaushofer K, Fratzl P. Towards bone replacement materials from calcium phosphates via rapid prototyping and ceramic gelcasting. Materials Science and Engineering: C, 2005, 25, 181–186.10.1016/j.msec.2005.01.014 ↗
13. Weiner S, Wagner H D. The material bone: Structure-mechanical function relations. Annual Review of Materials Science, 1998, 28, 271–298.10.1146/annurev.matsci.28.1.271 ↗
14. Kim J H, Niinomi M, Akahori T, Toda H. Fatigue properties of bovine compact bones that have different microstructures. International Journal of Fatigue, 2007, 29, 1039–1050.10.1016/j.ijfatigue.2006.09.018 ↗
15. Koester K J, Ager III J W, Ritchie R O. Aging and Fracture of human cortical bone and tooth dentin. Journal of the Minerals, Metals and Materials Society, 2008, 60, 33–38.10.1007/s11837-008-0068-1 ↗
16. Budyn E, Hoc T, Jonvaux J. Fracture strength assessment and aging signs detection in human cortical bone using an X-FEM multiple scale approach. Computational Mechanics, 2008, 42, 579–591.10.1007/s00466-008-0283-1 ↗