Microporous Annealed Particle (MAP) Scaffold Pore Size Influences Mesenchymal Stem Cell Metabolism and Proliferation Without Changing CD73, CD90, and CD105 Expression Over Two Weeks
Source abstract
Abstract
Abstract Scaffold pore architecture is shown to influence stem cell fate through various avenues. It is demonstrated that microporous annealed particle (MAP) microgel diameter can be tuned to control scaffold pore size and, in turn, modulate mesenchymal stem cell (MSC) survivability, proliferation, metabolism, and migration, thereby enhancing bioactivity and guiding future applications of MAP for regenerative medicine.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Graphene and Nanomaterials Applications · Electrospun Nanofibers in Biomedical Applications · Tissue Engineering and Regenerative Medicine
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
University of Virginia 415 Lane Road Charlottesville VA 22903 USA
Biomedical Engineering University of Virginia 415 Lane Road Charlottesville VA 22903‐3390 USA
Funding
National Institutes of Health · National Institute of Diabetes and Digestive and Kidney Diseases
References (33)
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