Polymeric complexes of lidocaine hydrochloride with poly(acrylic acid) and poly(2-hydroxyethyl vinyl ether)
Source abstract
Abstract
The specific interactions of local anesthetic lidocaine hydrochloride with poly(acrylic acid) and poly(2-hydroxyethyl vinyl ether), as well as in a triple system composed of the drug and both polymers, have been studied in aqueous solutions by viscometric, turbidimetric, potentiometric, and FTIR spectroscopic methods. The mechanism of the drug binding to the polymers and the structures of the polycomplexes formed are clarified.
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Research context
OpenAlex topics: Analytical Chemistry and Chromatography · Analytical Methods in Pharmaceuticals · Polymer Synthesis and Characterization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (18)
Show source-provided references
1. Mashkovski M. D. · 1998 · 1
2. Paavola A. · Pharm. Res. · 1995 · 12 · 199710.1023/A:1016264527738 ↗
3. Samchenko Yu. M. · Colloid J. (Russia) · 2000 · 62 · 117
4. Samchenko Yu. M. · Colloid J. (Russia) · 2001 · 63 · 102
5. Yahagi R. · J. Controlled Release · 1999 · 61 · 110.1016/S0168-3659(99)00111-X ↗
6. Gorner T. · J. Controlled Release · 1999 · 57 · 25910.1016/S0168-3659(98)00121-7 ↗
7. 10.1248/cpb.30.98010.1248/cpb.30.980 ↗
8. Nurkeeva Z. S. · Vysokomol. Soedin. Ser. A · 1987 · 29 · 932
9. Nurkeeva Z. S. · Vysokomol. Soedin. Ser. B · 1990 · 32 · 415
10. 10.1007/BFb001754910.1007/BFb0017549 ↗
11. Khutoryanskiy V. V. · Eur. Polym. J.
12. Nurkeeva, Z. S. and Shaikhutdinov, E. M. Proceedings of the 5th International Symposium on Polymers and Polymer Composites. pp.97Almaty, Kazakhstan: KazGU.
13. Molyneux, P. 1982. Water-Soluble Synthetic Polymers: Properties and Behavior, Vol. 2, 77CRC Press.
14. Nurkeeva Z. S. · Polym. Sci. B · 2001 · 43 · 925
15. 10.1248/cpb.37.136610.1248/cpb.37.1366 ↗
16. Oechsner, M. and Kiepert, S. Proc. 2nd World Meeting APGI/APV. pp.967Paris, France
17. Aksenova N. I. · Vysokomol. Soedin. Ser. A · 1998 · 40 · 403
18. 10.1248/cpb.29.81010.1248/cpb.29.810 ↗