Review Paper: A Review of the Cellular Response on Electrospun Nanofibers for Tissue Engineering
Source abstract
Abstract
Electrospinning has been employed extensively in tissue engineering to generate nanofibrous scaffolds from either natural or synthetic biodegradable polymers to simulate the cellular microenvironment. Electrospinning rapidly produces fibers of the nanolength scale and the process offers many opportunities to tailor the physical, chemical, and biological properties of a material for specific applications and cellular environments. There is growing evidence that nanofibers amplify certain biological responses such as contact guidance and differentiation, however this has not been fully exploited in tissue engineering. This review addresses the cellular interactions with electrospun scaffolds, with particular focus on neural, bone, cartilage, and vascular tissue regeneration. Some aspects of scaffold design, including architectural properties, surface functionalization and materials selection are also addressed.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Tissue Engineering and Regenerative Medicine · Advanced Sensor and Energy Harvesting Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Engineering, Division of Biological Engineering, Monash University, PO Box 69M, Victoria 3800, Australia, CRC for Polymers, 32 Business Park Drive, Notting Hill, VIC 3168, Australia
Department of Materials Engineering, Division of Biological Engineering, Monash University, PO Box 69M, Victoria 3800, Australia, , CRC for Polymers, 32 Business Park Drive, Notting Hill, VIC 3168, Australia
Australian Pulp and Paper Institute, Department of Chemical Engineering, Monash University, PO Box 69M, Victoria 3800, Australia
The Mental Health Research Institute of Victoria 155 Oak Street, Parkville, Victoria 3052, Australia
Howard Florey Institute, Gate 11, Royal Parade The University of Melbourne, VIC 3010, Australia
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