Spinal Fixation Device: A 6-Year Postimplantation Study
Source abstract
Abstract
Long-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.
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Research context
OpenAlex topics: Orthopaedic implants and arthroplasty · Spine and Intervertebral Disc Pathology · Pelvic and Acetabular Injuries
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India,
Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India
Department of Orthopedics Amritha Institute of Medical Sciences and Research Centre Kochi, Kerala, India
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