Preparation and characterization of chitosan and Aloe vera blends by co-precipitation for potential biomedical applications

Pâmella Rayo de Luar Campos Gonçalves; Paloma Souza; Marina Cardoso Nemitz; Mario Sergio Schultz; Leandro Louback da Silva; Amanda Ribeiro Guimarães; Cicero Wellington Brito Bezerra

doi:10.1177/08839115251351279

journal article·2025-07

Preparation and characterization of chitosan and Aloe vera blends by co-precipitation for potential biomedical applications

Pâmella Rayo de Luar Campos Gonçalves, Paloma Souza, Marina Cardoso Nemitz, Mario Sergio Schultz, Leandro Louback da Silva, Amanda Ribeiro Guimarães, Cicero Wellington Brito Bezerra

Journal of Bioactive and Compatible Polymers· Volume 40· Issue 4

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Source abstract

Abstract

Blends of chitosan and Aloe vera exudate in ratios of 75:25, 50:50, and 25:75 were prepared from aqueous solutions using the co-precipitation technique. This method offers notable advantages including simplicity, rapid processing, and efficient separation of interacting phases from non-associated components, resulting in products with greater purity and compositional control. Samples and precursors were characterized using Fourier-transform infrared spectroscopy (FTIR), thermal analysis (TG/DTG), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), swelling degree, antioxidant activity, and cell viability assay. The analyses indicated interactions between the biomaterials within the blend. Additionally, the biomaterials were found to be non-toxic, and the addition of Aloe vera exudate enhanced fibroblast cell viability. These findings underscore the significant potential of these biocompatible, antioxidant-rich blends, sustainably produced from renewable resources for a wide range of biotechnology applications.

Source: crossref · Quality: baseline

Research context

Biomaterials

OpenAlex topics: Nanocomposite Films for Food Packaging · biodegradable polymer synthesis and properties · Microencapsulation and Drying Processes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Rede de Biodiversidade e Biotecnologia da Amazônia Legal, Bionorte, Universidade Federal do Maranhão, São Luis, Maranhão, Brazil

Programa de Pós-graduação em Produtos Bioativos e Biociências, Universidade Federal do Rio de Janeiro-RJ, Macaé, Brazil

Instituto de Biodiversidade e Sustentabilidade de Macaé - NUPEM, Universidade Federal do Rio de Janeiro, Macaé-RJ, Brazil

Instituto de Ciências Farmacêuticas, Universidade Federal do Rio de Janeiro-RJ, Macaé, Brazil

Department of Organic Chemistry I, Centro de Innovación en Química Avanzada (ORFEO-CINQA), Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU) Manuel Lardizabal, Donostia/San Sebastián, Spain

Departamento de Química, Universidade Federal do Maranhão, São Luís, Maranhão, Brazil

Funding

Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão

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