journal article·1992-10

Investigation of Dynamic Behaviors of Asialoglycoprotein Receptors of Hepatocytes Using a Latex Probe Whose Surface Was Coated with Lactose-Carrying Polystyrene

Takeshi Kugumiya, Akio Yagawa, Atsushi Maeda, Hirokazu Nomoto, Seishiro Tobe, Kazukiyo Kobayashi, Takehisa Matsuda, Toshimasa Onishi, Toshihiro Akaike

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Abstract

Characteristic properties of oligosaccharide-substituted poly styrenes as a hepatocyte-specific culture substratum were investigated from the viewpoint of adsorption and recognition. X-ray photoelectron spectra sug gest that the adsorption of the polymer onto a polystyrene film occurred in near mono-molecular layer thickness of 10-25 Å in globular conformations. Distri bution and migration of asialoglycoprotein receptors on the surface of a hepato cyte was followed under a scanning electron microscope using a latex probe whose surface was coated with lactose-substituted polystyrene.
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Research context

OpenAlex topics: Analytical Chemistry and Chromatography · Enzyme Catalysis and Immobilization · Advanced Drug Delivery Systems

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Faculty of Technology, Tokyo University of Agriculture and Technology Koganei, Tokyo 184, Japan

Kanagawa Academy of Science and Technology Takatsu, Kawasaki 213, Japan

Faculty of Agriculture, Nagoya University Chikusa, Nagoya 464-01, Japan

National Cardiovascular Center Suita, Osaka 564, Japan

Nagase Chemicals Ltd., Tatsuno, Hyougo 679-41, Japan

Faculty of Bioscience and Technology, Tokyo Institute of Technology Midori, Yokohama 227, Japan

References (17)

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