DataVXJournal of Asian Ceramic SocietiesPaper
journal article·2016-03Open access

Fabrication of gadolinium hydroxide nanoparticles using ion-exchange resin and their MRI property

Y. Kobayashi, H. Morimoto, T. Nakagawa, Y. Kubota, K. Gonda, N. Ohuchi

Journal of Asian Ceramic Societies· Volume 4· Issue 1
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Source abstract

Abstract

This paper describes a method to fabricate gadolinium hydroxide (Gd(OH)3) nanoparticles. An opaque solution was prepared by adding basic anion exchange resin (BAER) to a Gd(NO3)3 aqueous solution at room temperature and aging the solution for 12–24 h; the solution became basic because of the exchange of H2O with OH−. The particles in the opaque solution have a needle structure, and their crystal structure was hexagonal Gd(OH)3. Their longitudinal and lateral average particle sizes tend to increase in the ranges of 175.0–222.1 and 33.9–52.3 nm when the aging time increases from 12 to 24 h, respectively. The relaxivity value for T1-weighted imaging was 0.79 mM−1 s−1 for the solution that was prepared at the aging time of 18 h, which was ca. 20% of that for a commercial Gd complex contrast agent.
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Research context

Nanomaterials

OpenAlex topics: Lanthanide and Transition Metal Complexes · Radioactive element chemistry and processing · Luminescence Properties of Advanced Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomolecular Functional Engineering, College of Engineering, Ibaraki UniversityNaka-narusawa-choHitachiIbaraki316-8511Japan

Department of Nano-Medical Science, Graduate School of Medicine, Tohoku UniversitySeiryo-machi, Aoba-kuSendai 980-8575Japan

Department of Medical Physics, Graduate School of Medicine, Tohoku UniversitySendaiMiyagi980-8575Japan

Department of Surgical Oncology, Graduate School of Medicine, Tohoku UniversitySeiryo-machi, Aoba-kuSendai 980-8574Japan

Funding

Ministry of Education, Culture, Sports, Science, and Technology · JSPS

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