journal article·2014-05Open access

Prevention of Staphylococcus Epidermidis Biofilm Formation Using Electrical Current

Jose L. Del Pozo, Mark S. Rouse, Gorane Euba, Kerryl E. Greenwood-Quaintance, Jayawant N. Mandrekar, James M. Steckelberg, Robin Patel

Abstract

A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 10 3 cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log 10 cfu/cm 2 were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log 10 cfu/cm 2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log 10 cfu/cm 2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.
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Research context

OpenAlex topics: Bacterial biofilms and quorum sensing · Planarian Biology and Electrostimulation · Microbial Inactivation Methods

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota - USA

Infectious Diseases Research Laboratory, Mayo Clinic College of Medicine, Rochester, Minnesota - USA

Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota - USA

Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota - USA

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