Raman Imaging of Layered Soft Contact Lenses
Source abstract
Abstract
Background Daily disposable contact lenses are gaining in popularity among practitioners and wearers for the improved ocular health and subjective outcomes they offer. Recently a novel daily disposable contact lens material with water gradient technology was introduced. Delefilcon A lenses consist of a 33% water content silicone hydrogel core and an outer hydrogel layer which is totally free of silicone and contains 80% water. Methods The aim of the present study was to confirm the layered structure of delefilcon A contact lenses. Thickness of hydrogel coating on the silicone hydrogel core was assessed using Raman spectroscopy. To investigate the layered structure of the material, depth spectra of the lenses were recorded. Results The results obtained suggest that at about 6 μm a boundary between the hydrogel layer and silicone hydrogel core exists, which is in good agreement with the manufacturer's data. Conclusions Data collected in this experiment confirm a water gradient at the delefilcon A lens surface.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Ocular Surface and Contact Lens · Electrowetting and Microfluidic Technologies · Advancements in Transdermal Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Physics, Adam Mickiewicz University, Poznań - Poland
NanoBioMedical Centre, Adam Mickiewicz University, Poznań - Poland
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