journal article·2021-01Open access

Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

Marko Magić, Božana Čolović, Saša Vasilijić, Nenad Tadić, Stevan Stojadinović, Vukoman Jokanović

Abstract

The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Titanium Alloys Microstructure and Properties · Orthopaedic implants and arthroplasty

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Dentistry, University of Belgrade, Belgrade, Serbia

Vinča Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia

Institute for Medical Research, Military Medical Academy, Medical Faculty MMA, University of Defence, Belgrade, Serbia

Faculty of Physics, University of Belgrade, Belgrade, Serbia

ALBOS d.o.o., Belgrade, Serbia

References (22)

Show source-provided references
1. 10.1007/s00776-011-0047-110.1007/s00776-011-0047-1 ↗
2. 10.1016/j.corsci.2014.01.01410.1016/j.corsci.2014.01.014 ↗
3. 10.1016/j.apsusc.2012.10.18310.1016/j.apsusc.2012.10.183 ↗
4. 10.1016/j.tsf.2015.09.07710.1016/j.tsf.2015.09.077 ↗
5. 10.1002/352760211910.1002/3527602119 ↗
6. 10.1016/S1350-4533(01)00050-910.1016/S1350-4533(01)00050-9 ↗
7. 10.1007/978-1-4615-5801-9_2110.1007/978-1-4615-5801-9_21 ↗
8. Testori T · Int J Oral Maxillofac Implants · 2001 · 16 · 193
9. 10.1016/0022-5088(77)90043-110.1016/0022-5088(77)90043-1 ↗
10. Mattsson L · 1985
11. 10.1016/S0142-9612(01)00307-610.1016/S0142-9612(01)00307-6 ↗
12. 10.1016/j.corsci.2010.05.04210.1016/j.corsci.2010.05.042 ↗
13. 10.1016/j.surfcoat.2011.06.01310.1016/j.surfcoat.2011.06.013 ↗
14. 10.1007/s10856-015-5408-410.1007/s10856-015-5408-4 ↗
15. 10.2138/am.2005.196310.2138/am.2005.1963 ↗
16. ISO 10993-5. Biological evaluation of medical devices, part 5. Geneva: ISO, 2009.
17. Sieuwert AM · Eur J Clin Chem Clin Biochem · 1995 · 33 · 813
18. 10.1016/S0091-679X(08)60508-710.1016/S0091-679X(08)60508-7 ↗
19. 10.1016/0009-8981(73)90174-510.1016/0009-8981(73)90174-5 ↗
20. Haugland R. · 2005 · 699
21. 10.1016/S1387-2656(05)11004-710.1016/S1387-2656(05)11004-7 ↗
22. 10.1111/j.1582-4934.2010.01013.x10.1111/j.1582-4934.2010.01013.x ↗