Tas1R3 Dependent and Independent Recognition of Sugars in the Urethra and the Role of Tuft Cells in this Process (Adv. Biology 6/2024)
Source abstract
Abstract
Urinary Tract Infection Increased sugar concentrations display risk factors for infections. Article number 2400117 by Klaus Deckmann and co-workers clarifies sugar monitoring in the urethra. Urethral tuft cells (UTC) are sentinels monitoring the urethral lumen and initiating protective mechanisms. Monitoring occurs via two pathways. A UTC/Tas1R3 dependent and a Tas1R3 independent pathway, found in both UTC and in other urethral epithelial cells. Sugars increases detrusor muscle activity UTC/Tas1R3 dependently.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Urinary and Genital Oncology Studies · Freezing and Crystallization Processes
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Affiliations
Institute for Anatomy and Cell Biology Justus‐Liebig‐University Giessen 35385 Giessen Germany
Leibniz Institute on Aging–Fritz Lipmann Institute 07745 Jena Germany
Division of Allergy and Clinical Immunology Brigham and Women's Hospital and Department of Medicine Harvard Medical School Boston MA 02115 USA
Centre des Sciences du Goût et de l'Alimentation CNRS INRAE Institut Agro Université de Bourgogne Dijon F‐21000 France
References
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