journal article·2021-01Open access

Wound Healing: Enhancement of Wound Healing Efficacy by Increasing the Stability and Skin‐Penetrating Property of bFGF Using 30Kc19α‐Based Fusion Protein (Adv. Biology 1/2021)

Haein Lee, Young‐Hyeon An, Tae Keun Kim, Jina Ryu, G. Kate Park, Mihn Jeong Park, Junghyeon Ko, Hyunbum Kim, Hak Soo Choi, Nathaniel S. Hwang, Tai Hyun Park

Advanced Biology· Volume 5· Issue 1

Abstract

The instability of recombinant basic fibroblast growth factor (bFGF) is a major disadvantage for its therapeutic use. In article number 2000176, Nathaniel S. Hwang, Tai Hyun Park, and co-workers fuse bFGF with 30Kc19α protein to enhance the stability and tissue penetration of bFGF. When applied to the wound site, 30Kc19α-bFGF fusion protein (blue-purple) facilitates wound regeneration by acting on fibroblasts and endothelial cells in the dermal layer
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Research context

OpenAlex topics: Wound Healing and Treatments · Periodontal Regeneration and Treatments · Tissue Engineering and Regenerative Medicine

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