Six decades of UHMWPE in reconstructive surgery
Source abstract
Abstract
Ultra-high molecular weight polyethylene (UHMWPE) materials have played a significant role in the field of reconstructive surgery, particularly as acetabular liners/sockets for total hip joint replacement (THR), and tibial inserts for total knee joint replacement (TKR). This review aims to provide a perspective on key elements regarding the processing–structure–property relationship of UHMWPE and derivatives. Much emphasis will be provided to discuss the clinically relevant properties of UHMWPE blend/composite formulation, Vitamin-E reinforced or highly crosslinked variants. In addition, we provide clinical insights into the role of wear debris in inflammation and osteolysis. The relatively unexplored domain of UHMWPE additive manufacturing. Finally, the relatively unexplored domain of UHMWPE additive manufacturing and the opportunities associated with the next generation of UHMWPE implants are highlighted.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Orthopaedic implants and arthroplasty · Total Knee Arthroplasty Outcomes · Orthopedic Infections and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Laboratory for Biomaterials, Materials Research Centre, Indian Institute of Science, Bengaluru, India
Translational Center of Excellence on Biomaterials for Orthopedic and Dental Applications, Indian Institute of Science, Bengaluru, India
Funding
Department of Science and Technology, Ministry of Science and Technology · Department of Biotechnology, Ministry of Science & Technology, Government of India
References (100+)
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