Biodegradable polyurethane/graphene oxide scaffolds for soft tissue engineering: in vivo behavior assessment
Source abstract
Abstract
In this work, 3D porous electrospun scaffolds based on DegraPol® (DP), a polyester urethane, with different concentrations of graphene oxide (GO) (0.0–2.0 wt%) were obtained. In order to produce scaffolds with increased porosity, solutions of DP and GO were co-electrospun with polyethylene oxide (PEO), which was subsequently removed. The electrospinning resulted in the formation of porous and fibrous scaffolds with superior elasticity. The colloidal Ag was successfully used as a novel method of scaffold sterilization. The results of the in vivo analysis showed scaffold degradation, absence of an inflammatory process and penetration of tissue cells in the scaffold.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Graphene and Nanomaterials Applications · Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Research Center for Environment and Materials, Academy of Sciences and Arts of the Republic of North Macedonia
Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University
Department of Polymer Materials, Tallinn University of Technology
ab medica
Faculty of Veterinary Medicine, Ss. Cyril and Methodius University
Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University
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