journal article·2025-05-24

Recent composition and applications of liposomes in cancer therapy

Iqra Noor Khan, Nida Arshad, Farwa Shaheen, Rabiya Shakoor, Ahmad Hassan, Muhammad Ahsan Waqar

Publisher page

Abstract

Nanoparticles are major focus of research nowadays. Liposomes are one of the nano-drug delivery system which is focus of research, especially for carrying chemotherapeutic agent for treatment of different cancers of body. Most common method of liposome preparation is thin film hydration method. For cancer therapy, liposome is being used for passive targeting due to leaky vessels of tumors which promotes enhanced and permeability effect and active targeting. Liposome is modified by slight alteration in their composition including long-circulating liposome, fusogenic liposome, immuno-liposome and stimuli-triggering liposome. This review extensively elaborates recent compositions and various applications of liposomes in cancer therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · RNA Interference and Gene Delivery · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Lahore University of Biological & Applied Sciences

Rashid Latif College of Pharmacy, Rashid Latif Medical Complex

Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Lahore University of Biological & Applied Sciences

Children Hospital and University of Child Health Sciences

Faculty of Pharmaceutical Sciences, Habib Institute of Health Sciences

References (100+)

Show source-provided references
1. Arora, G. Nanocarrier: A Boom or a Bane in the Medical Industry. Acta Sci. Pharma. Sci. 2019, 3, 08–23.
2. 10.1039/d0nh00605j10.1039/d0nh00605j ↗
3. 10.1007/s10311-018-00841-110.1007/s10311-018-00841-1 ↗
4. 10.3390/molecules2704137210.3390/molecules27041372 ↗
5. 10.1016/j.fbio.2020.10085710.1016/j.fbio.2020.100857 ↗
6. 10.1080/13543776.2019.167976710.1080/13543776.2019.1679767 ↗
7. 10.3389/fbioe.2021.70588610.3389/fbioe.2021.705886 ↗
8. 10.1016/j.addr.2021.01.01910.1016/j.addr.2021.01.019 ↗
9. 10.1016/j.ijpharm.2021.12057110.1016/j.ijpharm.2021.120571 ↗
10. 10.1021/acs.jmedchem.9b0051110.1021/acs.jmedchem.9b00511 ↗
11. 10.3390/nano1110255710.3390/nano11102557 ↗
12. 10.1016/j.addr.2020.07.00210.1016/j.addr.2020.07.002 ↗
13. 10.1007/s12668-022-00941-x10.1007/s12668-022-00941-x ↗
14. 10.1186/s11671-021-03553-810.1186/s11671-021-03553-8 ↗
15. 10.1039/d2bm01703b10.1039/d2bm01703b ↗
16. 10.1016/j.bpj.2014.05.03910.1016/j.bpj.2014.05.039 ↗
17. 10.1016/0001-8686(94)00223-y10.1016/0001-8686(94)00223-y ↗
18. 10.1016/j.ijpharm.2011.03.04910.1016/j.ijpharm.2011.03.049 ↗
19. 10.3389/fphar.2018.0008010.3389/fphar.2018.00080 ↗
20. 10.1016/j.heliyon.2022.e0939410.1016/j.heliyon.2022.e09394 ↗
21. 10.1007/s10973-011-1596-410.1007/s10973-011-1596-4 ↗
22. 10.3109/03639045.2012.66891210.3109/03639045.2012.668912 ↗
23. Allen, T.; Everest, J. Effect of Liposome Size and Drug Release Properties on Pharmacokinetics of Encapsulated Drug in Rats. J. Pharmacol. Exp. Ther. 1983, 226, 539–544.10.1016/S0022-3565(25)21638-X ↗
24. 10.3390/cancers1304067010.3390/cancers13040670 ↗
25. 10.1111/jphp.1309810.1111/jphp.13098 ↗
26. 10.1007/s10311-020-01022-910.1007/s10311-020-01022-9 ↗
27. 10.2174/138161282566619083015531910.2174/1381612825666190830155319 ↗
28. 10.1016/j.msec.2019.11029810.1016/j.msec.2019.110298 ↗
29. 10.3390/cancers1105064010.3390/cancers11050640 ↗
30. 10.1039/D0TB02996C10.1039/D0TB02996C ↗
31. 10.1021/acs.bioconjchem.9b0045610.1021/acs.bioconjchem.9b00456 ↗
32. 10.1016/j.jconrel.2020.02.01910.1016/j.jconrel.2020.02.019 ↗
33. 10.1038/s41578-020-00269-610.1038/s41578-020-00269-6 ↗
34. 10.1126/scirobotics.aaz951910.1126/scirobotics.aaz9519 ↗
35. 10.3390/pharmaceutics1603040010.3390/pharmaceutics16030400 ↗
36. 10.2217/nnm-2019-030810.2217/nnm-2019-0308 ↗
37. 10.1016/j.jddst.2020.10154910.1016/j.jddst.2020.101549 ↗
38. 10.1515/dmpt-2018-003210.1515/dmpt-2018-0032 ↗
39. 10.1016/j.cbi.2019.06.03310.1016/j.cbi.2019.06.033 ↗
40. 10.1615/CritRevTherDrugCarrierSyst.201902635810.1615/CritRevTherDrugCarrierSyst.2019026358 ↗
41. 10.1016/j.ijpharm.2021.12041310.1016/j.ijpharm.2021.120413 ↗
42. 10.1016/j.ijpharm.2020.11926910.1016/j.ijpharm.2020.119269 ↗
43. 10.1021/acsomega.3c0444410.1021/acsomega.3c04444 ↗
44. 10.1186/s11671-019-3164-y10.1186/s11671-019-3164-y ↗
45. 10.1080/08982104.2016.125424210.1080/08982104.2016.1254242 ↗
46. 10.1016/j.ijpharm.2021.12046310.1016/j.ijpharm.2021.120463 ↗
47. 10.1016/j.addr.2022.11439610.1016/j.addr.2022.114396 ↗
48. 10.1016/j.xphs.2017.05.02410.1016/j.xphs.2017.05.024 ↗
49. 10.1016/j.jpba.2018.06.01810.1016/j.jpba.2018.06.018 ↗
50. 10.1080/08982104.2021.188409310.1080/08982104.2021.1884093 ↗
51. 10.1021/acs.langmuir.0c0026210.1021/acs.langmuir.0c00262 ↗
52. 10.1021/acs.langmuir.2c0116910.1021/acs.langmuir.2c01169 ↗
53. 10.3390/ijms1902034610.3390/ijms19020346 ↗
54. 10.1021/acsbiomaterials.2c0149010.1021/acsbiomaterials.2c01490 ↗
55. 10.3389/fphar.2019.0140110.3389/fphar.2019.01401 ↗
56. 10.3390/ijms2106224410.3390/ijms21062244 ↗
57. 10.2174/156720181666619101611271710.2174/1567201816666191016112717 ↗
58. 10.1016/j.biomaterials.2023.12235010.1016/j.biomaterials.2023.122350 ↗
59. 10.1016/j.biopha.2018.11.01110.1016/j.biopha.2018.11.011 ↗
60. 10.2217/imt-2020-025810.2217/imt-2020-0258 ↗
61. 10.1016/j.omtm.2020.07.01510.1016/j.omtm.2020.07.015 ↗
62. 10.1016/j.biopha.2020.11105910.1016/j.biopha.2020.111059 ↗
63. 10.3390/pharmaceutics1309136510.3390/pharmaceutics13091365 ↗
64. 10.1016/j.ijpharm.2018.04.00110.1016/j.ijpharm.2018.04.001 ↗
65. 10.1016/j.colsurfa.2019.12405410.1016/j.colsurfa.2019.124054 ↗
66. 10.1080/08982104.2019.159344910.1080/08982104.2019.1593449 ↗
67. 10.1080/1061186X.2018.150277510.1080/1061186X.2018.1502775 ↗
68. 10.1007/s11095-018-2490-610.1007/s11095-018-2490-6 ↗
69. 10.1021/acs.molpharmaceut.0c0017010.1021/acs.molpharmaceut.0c00170 ↗
70. 10.3390/pharmaceutics1102006910.3390/pharmaceutics11020069 ↗
71. 10.3389/fphar.2022.83816810.3389/fphar.2022.838168 ↗
72. 10.1016/j.jconrel.2018.02.01510.1016/j.jconrel.2018.02.015 ↗
73. 10.1007/s11095-021-02986-110.1007/s11095-021-02986-1 ↗
74. 10.1016/j.eurpolymj.2022.11178110.1016/j.eurpolymj.2022.111781 ↗
75. 10.1016/j.esmoop.2021.10036510.1016/j.esmoop.2021.100365 ↗
76. 10.1080/17425247.2018.151774710.1080/17425247.2018.1517747 ↗
77. 10.1016/j.jconrel.2017.11.02610.1016/j.jconrel.2017.11.026 ↗
78. 10.1016/j.ijpharm.2017.10.02710.1016/j.ijpharm.2017.10.027 ↗
79. 10.1080/08982104.2018.155629310.1080/08982104.2018.1556293 ↗
80. Petrilli, R.; et al. Preparation of Immunoliposomes by Direct Coupling of Antibodies Based on a Thioether Bond. Methods Protocols 2018, 3, 229–237.
81. 10.1016/j.colsurfb.2020.11118510.1016/j.colsurfb.2020.111185 ↗
82. 10.1515/ntrev-2017-015410.1515/ntrev-2017-0154 ↗
83. 10.1039/C9TB02470K10.1039/C9TB02470K ↗
84. 10.2174/138945011766616020814414310.2174/1389450117666160208144143 ↗
85. 10.1080/1061186X.2024.234735610.1080/1061186X.2024.2347356 ↗
86. 10.1016/j.jconrel.2022.08.00110.1016/j.jconrel.2022.08.001 ↗
87. 10.1016/j.addr.2018.10.01210.1016/j.addr.2018.10.012 ↗
88. 10.1016/j.jconrel.2019.09.01810.1016/j.jconrel.2019.09.018 ↗
89. 10.1016/j.ejpb.2018.11.00110.1016/j.ejpb.2018.11.001 ↗
90. 10.2217/nnm-2018-051010.2217/nnm-2018-0510 ↗
91. 10.1016/j.jconrel.2022.05.05610.1016/j.jconrel.2022.05.056 ↗
92. 10.1007/s13346-018-0583-810.1007/s13346-018-0583-8 ↗
93. 10.3389/fonc.2022.80084210.3389/fonc.2022.800842 ↗
94. 10.2147/CMAR.S21323610.2147/CMAR.S213236 ↗
95. 10.1021/acs.molpharmaceut.9b0098810.1021/acs.molpharmaceut.9b00988 ↗
96. 10.1016/j.ejmech.2018.08.03410.1016/j.ejmech.2018.08.034 ↗
97. 10.1016/j.colsurfb.2021.11196710.1016/j.colsurfb.2021.111967 ↗
98. 10.1002/chem.20200052910.1002/chem.202000529 ↗
99. 10.1016/j.drudis.2021.05.01010.1016/j.drudis.2021.05.010 ↗
100. 10.1039/c7cs00663b10.1039/c7cs00663b ↗