Monitoring cell substrate interactions in exopolysaccharide-based films reinforced with chitin whiskers and starch nanoparticles used as cell substrates
Source abstract
Abstract
Exopolysaccharides (EPS) extracted from Nostoc commune cyanobacteria were used to prepare low-adhesion cell substrates for tumor-selective cell growth. The substrates were reinforced with chitin whiskers and starch nanoparticles and characterized using Fourier transform infrared spectroscopy, X-ray diffraction, and tensile tests. Two anchorage independent cells, green fluorescent protein-modified HeLa and THP-1 cells were seeded on the samples to assess their interaction with the composites. The results confirmed the cell–surface interaction of EPS-based composites. The mechanical properties of these films can be tailored by controlling the type and concentration of the reinforcement, which can be used in the design of different types of biomaterials.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Biocrusts and Microbial Ecology · Diatoms and Algae Research · Algal biology and biofuel production
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Mechanical Engineering, Pontificia Universidad Católica del Perú, Lima, Peru
Istituto Italiano di Tecnologia (IIT), Genova, Italy
Department of Engineering for Innovation, University of Salento, Lecce, Italy
Department of Physics, University of Genoa, Genova, Italy
Institute of Polymer Science and Technology (ICTP-CSIC), Madrid, Spain
Funding
National Council of Science, Technology and Technological Innovation (CONCYTEC-FONDECYT) · Vice-Rectorship for Research of the Pontificia Universidad Catolica del Peru (VRI-PUCP)
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