Novel silicone rubber with carboxyl grafted polyhedral oligomeric silsesquioxane (POSS-COOH) as a potential scaffold for soft tissue filling
Source abstract
Abstract
Due to the poor cell compatibility, capsular contracture is usually accompanied by the implantation of Silicone Rubber (SR). In this study, synthetical carboxyl grafted polyhedral oligomeric silsesquioxane (POSS-COOH) was incorporated into SR to prepare a composite filling material, namely POSS-COOH/SR. in vivo implantation showed that the occurrence of capsular formation around POSS-COOH/SR was inhibited, in vitro experiment showed cell improved proliferation and adhesion capability on POSS-COOH/SR. Through proteomics analysis, the extracellular matrix (ECM) regulatory protein in the cells on the surface of POSS-COOH/SR changed significantly. In summary, POSS-COOH/SR could be a better biomaterial to scaffold for soft tissue filling.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Tissue Engineering and Regenerative Medicine · Silicone and Siloxane Chemistry · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Plastic and Cosmetic Surgery, Xinqiao Hospital, The Army Medical University
Base for Drug Clinical Trial, Xinqiao Hospital, The Army Medical University
References (63)
Show source-provided references
1. 10.3390/ijms1904117110.3390/ijms19041171 ↗
2. 10.1093/asj/sjx11710.1093/asj/sjx117 ↗
3. 10.1016/j.actbio.2020.11.02010.1016/j.actbio.2020.11.020 ↗
4. 10.1097/GOX.000000000000280710.1097/GOX.0000000000002807 ↗
5. 10.1097/PRS.000000000000727710.1097/PRS.0000000000007277 ↗
6. 10.3390/ma1112239310.3390/ma11122393 ↗
7. 10.1007/s00266-020-01816-w10.1007/s00266-020-01816-w ↗
8. 10.1016/j.bjps.2020.02.04910.1016/j.bjps.2020.02.049 ↗
9. 10.1186/s40824-018-0147-510.1186/s40824-018-0147-5 ↗
10. 10.1590/0001-376520162015087410.1590/0001-3765201620150874 ↗
11. 10.1097/PRS.000000000000283710.1097/PRS.0000000000002837 ↗
12. 10.1016/j.msec.2016.12.04510.1016/j.msec.2016.12.045 ↗
13. 10.1002/jbm.a.3150810.1002/jbm.a.31508 ↗
14. 10.1007/s10856-013-5028-910.1007/s10856-013-5028-9 ↗
15. 10.1371/journal.pone.011150310.1371/journal.pone.0111503 ↗
16. 10.1371/journal.pone.009832010.1371/journal.pone.0098320 ↗
17. 10.1097/PRS.000000000000202210.1097/PRS.0000000000002022 ↗
18. 10.1016/j.actbio.2018.06.02210.1016/j.actbio.2018.06.022 ↗
19. 10.1016/j.actbio.2017.01.03310.1016/j.actbio.2017.01.033 ↗
20. 10.2147/MDER.S4952210.2147/MDER.S49522 ↗
21. 10.3233/BME-2009-057510.3233/BME-2009-0575 ↗
22. 10.1007/s11814-016-0296-y10.1007/s11814-016-0296-y ↗
23. 10.1021/ja105631j10.1021/ja105631j ↗
24. 10.1002/marc.20110012610.1002/marc.201100126 ↗
25. 10.2147/IJN.S1488110.2147/IJN.S14881 ↗
26. 10.1002/app.4964110.1002/app.49641 ↗
27. 10.3390/ma1108129810.3390/ma11081298 ↗
28. 10.1166/jnn.2021.1929010.1166/jnn.2021.19290 ↗
29. 10.3390/polym1102037310.3390/polym11020373 ↗
30. 10.1016/j.jmbbm.2013.07.00210.1016/j.jmbbm.2013.07.002 ↗
31. 10.1021/la303438t10.1021/la303438t ↗
32. 10.1155/2018/316703710.1155/2018/3167037 ↗
33. 10.1080/2000656X.2018.144461710.1080/2000656X.2018.1444617 ↗
34. 10.1155/2018/678497110.1155/2018/6784971 ↗
35. 10.1007/s00266-020-01876-y10.1007/s00266-020-01876-y ↗
36. 10.1002/jbm.a.3711510.1002/jbm.a.37115 ↗
37. 10.1007/s00266-021-02141-610.1007/s00266-021-02141-6 ↗
38. 10.1016/j.biomaterials.2007.03.01310.1016/j.biomaterials.2007.03.013 ↗
39. 10.1021/acsbiomaterials.8b0079510.1021/acsbiomaterials.8b00795 ↗
40. 10.1088/1748-6041/11/1/01502110.1088/1748-6041/11/1/015021 ↗
41. 10.1021/cr900201r10.1021/cr900201r ↗
42. 10.1039/c6sc04169h10.1039/c6sc04169h ↗
43. 10.1016/j.biomaterials.2005.01.01810.1016/j.biomaterials.2005.01.018 ↗
44. 10.1126/science.287.5455.98910.1126/science.287.5455.989 ↗
45. 10.1038/s41563-019-0504-310.1038/s41563-019-0504-3 ↗
46. 10.1016/j.biotechadv.2019.10742110.1016/j.biotechadv.2019.107421 ↗
47. 10.1073/pnas.200880111710.1073/pnas.2008801117 ↗
48. 10.3390/ijms212410.3390/ijms2124 ↗
49. 10.1074/jbc.274.26.1882110.1074/jbc.274.26.18821 ↗
50. 10.1038/cdd.2016.6610.1038/cdd.2016.66 ↗
51. 10.1160/TH13-02-015810.1160/TH13-02-0158 ↗
52. 10.1002/path.255710.1002/path.2557 ↗
53. 10.1016/j.biomaterials.2021.12080610.1016/j.biomaterials.2021.120806 ↗
54. 10.1097/PRS.0b013e3182131bea10.1097/PRS.0b013e3182131bea ↗
55. 10.1101/cshperspect.a02213710.1101/cshperspect.a022137 ↗
56. 10.1016/j.cbi.2018.07.00810.1016/j.cbi.2018.07.008 ↗
57. 10.1016/j.tcb.2008.08.00310.1016/j.tcb.2008.08.003 ↗
58. 10.1016/S0092-8674(02)00935-210.1016/S0092-8674(02)00935-2 ↗
59. 10.1038/onc.2011.2710.1038/onc.2011.27 ↗
60. 10.1016/j.ceb.2017.01.00310.1016/j.ceb.2017.01.003 ↗
61. 10.2174/15680090577493279810.2174/156800905774932798 ↗
62. 10.1038/nrm295710.1038/nrm2957 ↗
63. 10.1038/ncb0402-e9710.1038/ncb0402-e97 ↗