A comparative study of polycaprolactone–hydroxyapatite scaffold and collagen membrane carriers for recombinant human bone morphogenic protein-2 for guided bone regeneration
Source abstract
Abstract
The polycaprolactone-30% hydroxyapatite (PCL-30%HA) scaffolds were fabricated using Melt Stretching and Multilayer Deposition (MSMD) technique. Different models of guided bone regeneration were evaluated in rat models. Group A, the calvarial defects were covered with collagen membranes. Group B, the scaffolds were placed into the defects and covered with the membranes. 200 µL of the 400 µg/mL BMP solution was slowly dripped onto the membranes. Group C, the scaffolds were soaked in the BMP solution before being placed. Group D, only the scaffolds were placed. Conclusively, the Group C model could enhance new bone formation better than the other models.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Graphene and Nanomaterials Applications · Electrospun Nanofibers in Biomedical Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Prince of Songkla University
National Metal and Materials Technology Center, National Science and Technology Development Agency, Ministry of Science, Technology and Environment
Funding
Thailand Research Fund · Cranio-Maxillofacial Hard Tissue Engineering Center · Department of Oral and Maxillofacial Surgery · Faculty of Dentistry · Prince of Songkla University
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