journal article·2024-12-11Open access

Advanced biomaterials for tendon repair: development and application

Ye Shen, Yan Xu, Jishizhan Chen

Abstract

Professional sports such as tennis training require repetitive shoulder movements, which can result in tendon fatigue and injury due to overuse.This injury usually occurs when an incorrect force is applied or when the tendon is overused.Because the tendon lacks blood vessels, the repair process is slow and ineffective.The treatment of tendon injuries has always been a clinical challenge.In addition to conventional surgery and nonoperative conservative treatment, biomaterial-based scaffolds may be a solution.In this review, we described several of the most popular biomaterials for tendon repair and presented the latest research advances.These biomaterials include protein-based biomaterials, carbohydrates, glycosaminoglycans, and acellular matrices.They have shown improved tendon repair ability both in vitro and in vivo.However, no gold standard has been established, and further experiments are needed.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Tendon Structure and Treatment · Shoulder Injury and Treatment · Laser Applications in Dentistry and Medicine

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Nursing, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, People’s Republic of China

UCL Mechanical Engineering, Torrington Place, University College London, London WC1E 7JE, UK

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