Polycaprolactone/multi-walled carbon nanotube nerve guidance conduits with tunable channels fabricated via novel extrusion-stretching method for peripheral nerve repair
Source abstract
Abstract
Multi-channeled nerve guidance conduit is a prospective way to repair peripheral nerve injury, which is still difficult to be fabricated. A novel extrusion-stretching method was utilized in this study to produce multi-walled carbon nanotubes (MWCNTs) loaded multi-channeled nerve conduits with improved flexibility and versatility. The channels and geography of the conduits were tunable. The results showed that the mechanical properties of the multi-channeled nerve conduits were suitable for peripheral nerve restoration. MWCNTs increased the biocompatibility of the multi-channeled nerve conduits. This study proved that the MWCNTs loaded multi-channeled produced by extrusion-stretching method have great potential to repair peripheral nerve injury.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nerve injury and regeneration · Graphene and Nanomaterials Applications · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, China
Tianjin Key Laboratory of Bio-electromagnetic and Neural Engineering, Hebei University of Technology, Tianjin, China
Hebei Key Laboratory of Bioelectromagnetics and Neuroengineering, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, China
Nanotechnology and Integrated Bioengineering Centre, Jordanstown Campus, University of Ulster, Newtownabbey, United Kingdom
Funding
Natural Science Foundation of Hebei Province
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