journal article·2026-06-12Open access

MCA-FM: Robust Non-Invasive Fetal ECG Extraction via Minimal Channel Attention and Flow Matching

Qingqing Duan, Xinyu Hu, Yuwei Zhang, Zhijun Xiao, Chengyu Liu

Applied Sciences· Volume 16· Issue 12

Abstract

Non-invasive fetal electrocardiogram (FECG) extraction from maternal abdominal ECG (AECG) is crucial for prenatal monitoring but remains challenging due to strong interference from maternal ECG (MECG), baseline drift, and noise. We propose an FECG extraction method based on minimal channel attention (MCA) and flow matching (FM), learning a deterministic mapping from AECG to FECG via a probabilistic path. To balance the preservation of physiological signals and separation of interference, we employ bridge variance scheduling for the diffusion process. Target matching loss is introduced to regress the FECG directly, enhancing training stability and waveform fidelity. For feature selection, a minimal channel attention module with global average pooling and a single linear layer is embedded after feature extraction, capturing cross-channel dependencies with minimal parameters. Enhanced residual connections are incorporated to retain underlying features and optimize gradient flow in deep networks. Experiments on two public datasets (ADDB and BDDB) with a leave-one-out cross-validation strategy show that our method achieves average Pearson correlation coefficients (PCCs) of 0.94 ± 0.050 on ADDB and 0.91 ± 0.122 on BDDB, demonstrating robust performance across diverse real-world recording conditions. The method balances high accuracy with efficient feature extraction, offering a reliable solution for non-invasive fetal heart health monitoring.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: ECG Monitoring and Analysis · Neonatal and fetal brain pathology · Cardiac electrophysiology and arrhythmias

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Computer Science, Jiangsu University of Science and Technology, Zhenjiang 212003, China

School of Information and Artificial Intelligence, Yangzhou University, Yangzhou 225127, China

The State Key Laboratory of Bioelectronics, School of Instrument Science and Engineering, Southeast University, Nanjing 210096, China

Funding

National Natural Science Foundation of China · the National Key Research and Development Program of China · the Research Start-up Funding for High-level Talent of Jiangsu University of Science and Technology

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