journal article·2026-04-10Open access

Artificial Intelligence Architectures in Oral Rehabilitation: A Focused Review of Deep Learning Models for Implant Planning, Prosthodontic Design, and Peri-Implant Diagnosis

Hossam Dawa, Carlos Aroso, Ana Sofia Vinhas, José Manuel Mendes, Arthur Rodriguez Gonzalez Cortes

Applied Sciences· Volume 16· Issue 8

Abstract

Deep learning is increasingly integrated into oral rehabilitation workflows, particularly in implant planning, prosthodontic design automation, and peri-implant diagnosis. However, reported performance is heterogeneous and difficult to compare across tasks, modalities, and validation designs. The goal of this study was to critically analyze deep learning architecture families applied to oral rehabilitation and to provide task-driven selection guidance supported by an evidence table reporting dataset characteristics, validation strategy, and performance metrics. A focused narrative review was conducted using transparent, database-specific search criteria (final n = 10 included studies), emphasizing implant planning (cone–beam computed tomography [CBCT]-based segmentation), prosthodontic design (intraoral scan [IOS]/mesh inputs), and peri-implant diagnosis (periapical/panoramic radiographs). Evidence certainty for each clinical task was assessed using GRADE-informed ratings (High/Moderate/Low/Very Low). Extracted variables included clinical task, imaging modality, dataset size, architecture, validation strategy (internal vs. internal + external), split level, ground truth protocol, and performance metrics. A structured computational and hardware feasibility analysis was conducted for each architecture family to support real-world deployment planning. Encoder–decoder networks (U-Net/nnU-Net) dominate CBCT segmentation for implant planning, while detection architectures (Faster R-CNN, YOLO) support implant localization and peri-implant assessment on radiographs. Generative models (3D GANs, transformer-based point-to-mesh networks) enable crown design from three-dimensional scans. Hybrid CNN–Transformer architectures show promise for multimodal CBCT–IOS fusion, though direct evidence from the included studies remains limited to a single study. External validation remains uncommon yet essential given the risk of domain shift. In conclusion, architecture selection should be anchored to task geometry (2D vs. 3D), artifact burden, and required clinical output type. Reporting standards should prioritize dataset transparency, validation rigor, multi-center external testing, and uncertainty-aware outputs.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Dental Radiography and Imaging · Dental Implant Techniques and Outcomes · Dental Health and Care Utilization

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

UNIPRO—Oral Pathology and Rehabilitation Research Unit, Instituto Universitário de Ciências da Saúde, CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal

AI&Health—Investigation in AI Applied to Health Unit, Instituto Politécnico de Saúde do Norte, CESPU, Rua José António Vidal 81, 4760-409 Famalicão, Portugal

Department of Dental Surgery, Faculty of Dental Surgery, University of Malta, MSD 2080 Msida, Malta

References (55)

Show source-provided references
1. Attitudes and perceptions of Australian dentists and dental students towards applications of artificial intelligence in dentistry: A survey10.1111/eje.13042 ↗
2. Deep learning for caries detection: A systematic review10.1016/j.jdent.2022.104115 ↗
3. Digital maxillomandibular relationship recording
4. Academy of Prosthodontics (2017). The glossary of prosthodontic terms: Ninth edition. J. Prosthet. Dent., 117, e1–e105.10.1016/j.prosdent.2016.12.001 ↗
5. Bitewing radiography for detection of caries lesions10.1177/154405910408301s14 ↗
6. Imaging methods in periodontology10.1046/j.0906-6713.2003.003423.x ↗
7. Observer agreement in the detection of proximal caries with direct digital intraoral radiography10.1016/S1079-2104(98)90407-3 ↗
8. Challenges in detecting various peri-implant bone defects on modified intraoral oblique radiographic projections: Evaluation of an artificial mandibular model10.1007/s11282-024-00798-8 ↗
9. Ibraheem, W.I., Jain, S., Ayoub, M.N., Namazi, M.A., Alfaqih, A.I., Aggarwal, A., Meshni, A.A., Almarghlani, A., and Alhumaidan, A.A. (2025). Assessment of the diagnostic accuracy of artificial intelligence software in identifying common periodontal and restorative dental conditions in intraoral periapical radiographs. Diagnostics, 15.10.3390/diagnostics15111432 ↗
10. Guldiken, I.N., Tekin, A., Kanbak, T., Kahraman, E.N., and Özcan, M. (2025). Prognostic evaluation of lower third molar eruption status from panoramic radiographs using artificial intelligence-supported machine and deep learning models. Bioengineering, 12.10.3390/bioengineering12111176 ↗
11. Roongruangsilp, P., and Khongkhunthian, P. (2021). The learning curve of artificial intelligence for dental implant treatment planning: A descriptive study. Appl. Sci., 11.10.3390/app112110159 ↗
12. Tayeb, S., Barausse, C., Pellegrino, G., Sansavini, M., Pistilli, R., and Felice, P. (2025). Comparing artificial intelligence (ChatGPT, Gemini, DeepSeek) and oral surgeons in detecting clinically relevant drug–drug interactions in dental therapy. Appl. Sci., 15.10.3390/app152312851 ↗
13. The use and performance of artificial intelligence applications in dental and maxillofacial radiology: A systematic review10.1259/dmfr.20190107 ↗
14. A narrative review: Dental radiology with deep learning
15. SANRA—A scale for the quality assessment of narrative review articles10.1186/s41073-019-0064-8 ↗
16. DentalSegmentator: Robust open-source deep learning-based CT and CBCT image segmentation10.1016/j.jdent.2024.105130 ↗
17. Kurt Bayrakdar, S., and Orhan, K. (2021). A deep learning approach for dental implant planning in cone-beam computed tomography images. BMC Med. Imaging, 21.10.1186/s12880-021-00618-z ↗
18. Developing an Artificial Intelligence Solution to Autosegment the Edentulous Mandibular Bone for Implant Planning10.1055/s-0043-1764425 ↗
19. Automated detection and labelling of teeth and small edentulous regions on cone-beam computed tomography using deep learning10.1016/j.jdent.2022.104139 ↗
20. Deep learning-enabled 3D multimodal fusion of cone-beam CT and intraoral mesh scans for clinically applicable tooth–bone reconstruction10.1016/j.patter.2023.100825 ↗
21. Morphology and mechanical performance of dental crown designed by 3D-DCGAN10.1016/j.dental.2023.02.001 ↗
22. Personalized dental crown design: A point-to-mesh completion network10.1016/j.media.2024.103439 ↗
23. Jang, B., Kim, S., Yun, P.S., Jang, H.S., Seong, Y.W., Yang, H.S., and Chang, J.S. (2022). Accurate detection and classification of dental implant and peri-implant tissue using Faster R-CNN. BMC Oral Health, 22.10.1186/s12903-022-02539-x ↗
24. Cha, J.-Y., Yoon, H.-I., Yeo, I.-S., Huh, K.-H., and Han, J.-S. (2021). Peri-implant bone loss measurement using a region-based convolutional neural network on dental Periapical Radiographs. J. Clin. Med., 10.10.3390/jcm10051009 ↗
25. Mao, Y.-C., Chen, C.-A., Lin, Y.-J., Chang, Y.-J., Wei, S.-T., Chen, S.-L., Chen, T.-Y., Li, K.-C., Tu, W.-C., and Abu, P.A.R. (J. Dent. Sci., 2025). Automated assessment of peri-implant disease severity by deep learning and image processing in periapical radiographs, J. Dent. Sci., in press.10.1016/j.jds.2025.08.015 ↗
26. Deep learning10.1038/nature14539 ↗
27. Detection and diagnosis of dental caries using a deep learning-based convolutional neural network algorithm10.1016/j.jdent.2018.07.015 ↗
28. Krizhevsky, A., Sutskever, I., and Hinton, G.E. (2012). ImageNet classification with deep convolutional neural networks. Advances in Neural Information Processing Systems 25, Curran Associates, Inc.. Available online: https://proceedings.neurips.cc/paper/2012/hash/c399862d3b9d6b76c8436e924a68c45b-Abstract.html.
29. He, K., Zhang, X., Ren, S., and Sun, J. (2016, January 27–30). Deep residual learning for image recognition. Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (CVPR 2016), Las Vegas, NV, USA.10.1109/CVPR.2016.90 ↗
30. Faster R-CNN: Towards real-time object detection with region proposal networks10.1109/TPAMI.2016.2577031 ↗
31. Deep learning for the radiographic detection of apical lesions10.1016/j.joen.2019.03.016 ↗
32. Redmon, J., Divvala, S., Girshick, R., and Farhadi, A. (2016, January 27–30). You only look once: Unified, real-time object detection. Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (CVPR 2016), Las Vegas, NV, USA.10.1109/CVPR.2016.91 ↗
33. Tooth detection and numbering in panoramic radiographs using convolutional neural networks10.1259/dmfr.20180051 ↗
34. Ronneberger, O., Fischer, P., and Brox, T. (2015). U-Net: Convolutional networks for biomedical image segmentation. Medical Image Computing and Computer-Assisted Intervention—MICCAI 2015, Springer.10.1007/978-3-319-24574-4_28 ↗
35. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., and Ronneberger, O. (2016). 3D U-Net: Learning dense volumetric segmentation from sparse annotation. Medical Image Computing and Computer-Assisted Intervention—MICCAI 2016, Springer.10.1007/978-3-319-46723-8_49 ↗
36. nnU-Net: A self-configuring method for deep learning-based biomedical image segmentation10.1038/s41592-020-01008-z ↗
37. Evaluation of a metal artifact reduction algorithm and an optimization filter in CBCT10.1016/j.oooo.2020.02.005 ↗
38. Dosovitskiy, A., Beyer, L., Kolesnikov, A., Weissenborn, D., Zhai, X., Unterthiner, T., Dehghani, M., Minderer, M., Heigold, G., and Gelly, S. (2021, January 3–7). An image is worth 16 × 16 words: Transformers for image recognition at scale. Proceedings of the 9th International Conference on Learning Representations (ICLR 2021), Virtual Event. Available online: https://openreview.net/forum?id=YicbFdNTTy.
39. Vaswani, A., Shazeer, N., Parmar, N., Uszkoreit, J., Jones, L., and Gomez, A.N. (2017). Attention is All You Need. (NeurIPS 2017), Curran Associates, Inc.. Available online: https://arxiv.org/abs/1706.03762.
40. Liu, Z., Lin, Y., Cao, Y., Hu, H., Wei, Y., Zhang, Z., Lin, S., and Guo, B. (2021, January 11–17). Swin Transformer: Hierarchical vision transformer using shifted windows. Proceedings of the IEEE/CVF International Conference on Computer Vision (ICCV 2021), Montreal, QC, Canada.10.1109/ICCV48922.2021.00986 ↗
41. Chen, T., Kornblith, S., Norouzi, M., and Hinton, G. (2020, January 13–18). A simple framework for contrastive learning of visual representations. Proceedings of the 37th International Conference on Machine Learning (ICML 2020), Virtual Event. Available online: http://proceedings.mlr.press/v119/chen20j.html.
42. Robust and data-efficient generalization of self-supervised machine learning for diagnostic imaging10.1038/s41551-023-01049-7 ↗
43. TransUNet: Rethinking the U-Net architecture design for medical image segmentation through the lens of transformers10.1016/j.media.2024.103280 ↗
44. Goodfellow, I., Pouget-Abadie, J., Mirza, M., Xu, B., Warde-Farley, D., Ozair, S., Courville, A., and Bengio, Y. (2014). Generative adversarial nets. Advances in Neural Information Processing Systems 27 (NIPS 2014), Curran Associates, Inc.. Available online: https://arxiv.org/abs/1406.2661.
45. Mirza, M., and Osindero, S. (2014). Conditional generative adversarial nets. arXiv.
46. Ho, J., Jain, A., and Abbeel, P. (2020). Denoising diffusion probabilistic models. Advances in Neural Information Processing Systems 33 (NeurIPS 2020), Curran Associates, Inc.. Available online: https://proceedings.neurips.cc/paper/2020/hash/4c5bcfec8584af0d967f1ab10179ca4b-Abstract.html.
47. Dhariwal, P., and Nichol, A. (2021). Diffusion models beat GANs on image synthesis. Advances in Neural Information Processing Systems 34 (NeurIPS 2021), Curran Associates, Inc.. Available online: https://proceedings.neurips.cc/paper/2021/hash/49ad23d1ec9fa4bd8d77d02681df5cfa-Abstract.html.
48. Song, J., Meng, C., and Ermon, S. (2021, January 3–7). Denoising diffusion implicit models. Proceedings of the 9th International Conference on Learning Representations (ICLR 2021), Virtual Event. Available online: https://openreview.net/forum?id=St1giarCHLP.
49. An important morphological feature of the face: Upper lip length
50. Occlusal scheme for tooth-supported fixed partial dentures
51. Foundation models for generalist medical artificial intelligence10.1038/s41586-023-05881-4 ↗
52. Huang, X., Xiao, F., He, D., Gao, A., Li, D., Zhang, X., Zhang, S., and Wang, X. (2025). Towards generalist intelligence in dentistry: Vision foundation models for oral and maxillofacial radiology. arXiv.
53. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement10.1161/CIRCULATIONAHA.114.014508 ↗
54. Checklist for Artificial Intelligence in Medical Imaging (CLAIM): A guide for authors and reviewers10.1148/ryai.2020200029 ↗
55. Revisiting the role of review articles in the age of AI-agents: Integrating AI-reasoning and AI-synthesis reshaping the future of scientific publishing10.1007/s44411-025-00106-8 ↗