journal article·2026-01-28Open access

Sleep Staging Method Based on Multimodal Physiological Signals Using Snake–ACO

Wenjing Chu, Chen Wang, Liuwang Yang, Lin Guo, Chuquan Wu, Binhui Wang, Xiangkui Wan

Applied Sciences· Volume 16· Issue 3

Abstract

Non-invasive electrocardiogram (ECG) and respiratory signals are easy to acquire via low-cost sensors, making them promising alternatives for sleep staging. However, existing methods using these signals often yield insufficient accuracy. To address this challenge, we incrementally optimized the sleep staging model by designing a structured experimental workflow: we first preprocessed respiratory and ECG signals, then extracted fused features using an enhanced feature selection technique, which not only reduces redundant features, but also significantly improves the class discriminability of features. The resulting fused features serve as a reliable feature subset for the classifier. In the meantime, we proposed a hybrid optimization algorithm that integrates the snake optimization algorithm (SO) and ant colony optimization algorithm (ACO) for automated hyperparameter optimization of support vector machines (SVMs). Experiments were conducted using two PSG-derived public datasets, the Sleep Heart Health Study (SHHS) and MIT-BIH Polysomnography Database (MIT-BPD), to evaluate the classification performance of multimodal features compared with single-modal features. Results demonstrate that the bimodal staging using SHHS multimodal signals significantly outperformed single-modal ECG-based methods, and the overall accuracy of the SHHS dataset was improved by 12%. The SVM model optimized using the hybrid Snake–ACO algorithm achieved an average accuracy of 89.6% for wake versus sleep classification on the SHHS dataset, representing a 5.1% improvement over traditional grid search methods. Under the subject-independent partitioning experiment, the wake versus sleep classification task maintained good stability with only a 1.8% reduction in accuracy. This study provides novel insights for non-invasive sleep monitoring and clinical decision support.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Obstructive Sleep Apnea Research · Non-Invasive Vital Sign Monitoring · EEG and Brain-Computer Interfaces

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Hubei Key Laboratory for High-Efficiency Utilization of Solar Energy and Operation Control of Energy Storage System, Hubei University of Technology, Wuhan 430068, China

Puleap (Wuhan) Medical Technology Co., Ltd., Wuhan 430068, China

Funding

Wuhan Knowledge Innovation Special Project of China

References (33)

Show source-provided references
1. Si, K., Dong, K., Lu, J., Zhao, L., Xiang, W., Li, J., and Liu, C. (2023). A U-Sleep Model for Sleep Staging Using Electrocardiography and Respiration Signals. Asian-Pacific Conference on Medical and Biological Engineering, Springer Nature.10.1007/978-3-031-51455-5_54 ↗
2. Yue, H., Chen, Z., Guo, W., Sun, L., Dai, Y., Wang, Y., Ma, W., Fan, X., Wen, W., and Lei, W. (2024). Research and application of deep learning-based sleep staging: Data, modeling, validation, and clinical practice. Sleep Med. Rev., 74.10.1016/j.smrv.2024.101897 ↗
3. Comparative analysis of sleep parameters and structures derived from wearable flexible electrode sleep patches and polysomnography in young adults10.1152/jn.00465.2023 ↗
4. Perslev, M., Darkner, S., Kempfner, L., Nikolic, M., Jennum, P.J., and Igel, C. (2021). U-Sleep: Resilient high-frequency sleep staging. npj Digit. Med., 4.10.1038/s41746-021-00440-5 ↗
5. Yang, C.Y., Chen, P.C., and Huang, W.C. (2023). Cross-domain transfer of EEG to EEG or ECG learning for CNN classification models. Sensors, 23.10.3390/s23052458 ↗
6. Sleep staging algorithm based on smartwatch sensors for healthy and sleep apnea populations10.1016/j.sleep.2024.05.033 ↗
7. A multi-class automatic sleep staging method based on long short-term memory network using single-lead electrocardiogram signals10.1109/ACCESS.2019.2924980 ↗
8. Byeon, Y.H., and Kwak, K.C. (2024). An Ensemble Deep Neural Network-Based Method for Person Identification Using Electrocardiogram Signals Acquired on Different Days. Appl. Sci., 14.10.3390/app14177959 ↗
9. Sleep stages classification based on heart rate variability and random forest10.1016/j.bspc.2013.06.001 ↗
10. Wang, J.S., Shih, G.R., and Chiang, W.C. (2012, January 5–7). Sleep stage classification of sleep apnea patients using decision-tree-based support vector machines based on ECG parameters. Proceedings of the 2012 IEEE-EMBS International Conference on Biomedical and Health Informatics, Hong Kong, China.
11. Analyzing respiratory effort amplitude for automated sleep stage classification10.1016/j.bspc.2014.08.001 ↗
12. Sleep staging using cardiorespiratory signals10.1007/s11818-007-0314-8 ↗
13. An evaluation of cardiorespiratory and movement features with respect to sleep-stage classification10.1109/JBHI.2013.2276083 ↗
14. Sharan, R.V., Takeuchi, H., Kishi, A., and Yamamoto, Y. (2024). Macro-sleep staging with ECG-derived instantaneous heart rate and respiration signals and multi-input 1D CNN-BiGRU. IEEE Trans. Instrum. Meas., 73.10.1109/TIM.2024.3481551 ↗
15. Automatic sleep identification using the novel hybrid feature selection method for HRV signal10.1016/j.cmpbup.2022.100050 ↗
16. Feature selection by mRMR method for heart disease diagnosis10.1109/ACCESS.2022.3207492 ↗
17. Hashim, F.A., and Hussien, A.G. (2022). Snake Optimizer: A novel meta-heuristic optimization algorithm. Knowl.-Based Syst., 242.10.1016/j.knosys.2022.108320 ↗
18. Zhou, X., Ma, H., Gu, J., Chen, H., and Deng, W. (2022). Parameter adaptation-based ant colony optimization with dynamic hybrid mechanism. Eng. Appl. Artif. Intell., 114.10.1016/j.engappai.2022.105139 ↗
19. Development of the polysomnographic database on CD-ROM10.1046/j.1440-1819.1999.00527.x ↗
20. The National Sleep Research Resource: Towards a sleep data commons10.1093/jamia/ocy064 ↗
21. The Sleep Heart Health Study: Design, rationale, and methods
22. Clinical Fusion for Real-Time Complex QRS Pattern Detection in Wearable ECG Using the Pan-Tompkins Algorithm10.54216/FPA.120214 ↗
23. Fonseca, P., Long, X., Radha, M., Haakma, R., Aarts, R.M., and Rolink, J. (2015). Sleep stage classification with ECG and respiratory effort. Physiol. Meas., 36.10.1088/0967-3334/36/10/2027 ↗
24. Recognizing seizure using Poincaré plot of EEG signals and graphical features in DWT domain
25. Haemmerle, P., Hennings, E., Eken, C., Aeschbacher, S., Coslovsky, M., Schlageter, V., Osswald, S., Kuehne, M., and Zuern, C.S. (2022). Impaired heart rate variability triangular index predicts stroke and systemic embolism in patients with atrial fibrillation. Europace, 24.10.1093/europace/euac053.161 ↗
26. Zhang, Z., Chen, H., Ning, P., Yang, N., and Yuan, D. (2024, January 9–12). CAKD: A correlation-aware knowledge distillation framework based on decoupling Kullback-Leibler divergence. Proceedings of the 2024 IEEE International Conference on Data Mining (ICDM), Abu Dhabi, United Arab Emirates.10.1109/ICDM59182.2024.00122 ↗
27. Wang, H., Li, G., and Wang, Z. (2023). Fast SVM classifier for large-scale classification problems. Inf. Sci., 642.10.1016/j.ins.2023.119136 ↗
28. Evaluating reliability in wearable devices for sleep staging10.1038/s41746-024-01016-9 ↗
29. Learning from imbalanced data
30. Urtnasan, E., Park, J.U., Joo, E.Y., and Lee, K.J. (2022). Deep convolutional recurrent model for automatic scoring sleep stages based on single-lead ECG signal. Diagnostics, 12.10.3390/diagnostics12051235 ↗
31. Jain, M., Saihjpal, V., Singh, N., and Singh, S.B. (2022). An overview of variants and advancements of PSO algorithm. Appl. Sci., 12.10.3390/app12178392 ↗
32. Migliorini, M., Bianchi, A.M., Nisticò, D., Kortelainen, J., Arce-Santana, E., Cerutti, S., and Mendez, M.O. (September, January 31). Automatic sleep staging based on ballistocardiographic signals recorded through bed sensors. Proceedings of the 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, Buenos Aires, Argentina.10.1109/IEMBS.2010.5627217 ↗
33. Canisius, S., Ploch, T., Gross, V., Jerrentrup, A., Penzel, T., and Kesper, K. (2008, January 20–25). Detection of sleep disordered breathing by automated ECG analysis. Proceedings of the 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vancouver, BC, Canada.10.1109/IEMBS.2008.4649733 ↗