journal article·2025-12-11Open access

Implementation of an Interactive Clinical Simulator Based on Facial Anatomy: An Enhanced Model for Injection Training

Ji-Young Son, Sang-Chul Choi, Hyeong-Seok Choi, Il Kim, Byeong-Ha Kim, Donghun Yang, Seung-Ho Han

Applied Sciences· Volume 15· Issue 24

Abstract

Minimally invasive facial procedures are widely performed in clinical medicine but remain associated with severe complications such as necrosis or blindness, often resulting from insufficient anatomical understanding and limited procedural training. To address these challenges, this study developed an anatomically accurate clinical simulator for facial injection training. A three-dimensional polygonal facial model was constructed using standardized anatomical datasets reflecting skeletal dimensions, soft tissue characteristics and the average arterial distribution of East Asian faces. This model was integrated into simulation software connected to a facial silicone dummy with realistic tissue texture and an optical tracking system providing sub-millimeter precision. Each anatomical structure, including muscles, vessels and nerves, was digitally annotated and linked to interactive visualization tools. During training, the simulator simultaneously reflected the real-time needle trajectory and insertion depth; when the needle tip approached a high-risk structure, such as the supraorbital artery, alerts were automatically triggered. This feedback enabled trainees to recognize unsafe injection zones and adjust their technique accordingly. The system provided a realistic, repeatable and safe environment for improving anatomical comprehension and procedural accuracy. This study proposes an innovative applied simulation system that may enhance medical education and clinical safety in facial injection procedures.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Dental Research and COVID-19 · Dental Anxiety and Anesthesia Techniques · Facial Trauma and Fracture Management

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Anatomy, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea

Ewha Medical Academy, Ewha Womans University Medical Center, Seoul 07804, Republic of Korea

Surgical Mind Inc., Seoul 07547, Republic of Korea

BH 3D Art Center, Seoul 04782, Republic of Korea

Korea Institute of Science and Technology Information, Daejeon 34141, Republic of Korea

Funding

Ministry of Health & Welfare, Republic of Korea · Korea Institute of Science and Technology Information

References (47)

Show source-provided references
1. Garrouste-Orgeas, M., Philippart, F., Bruel, C., Max, A., Lau, N., and Misset, B. (2012). Overview of medical errors and adverse events. Ann. Intensive Care, 2.10.1186/2110-5820-2-2 ↗
2. A Legal Analysis of the Precedents of Medical Disputes in the Cosmetic Surgery Field10.5999/aps.2016.43.3.278 ↗
3. Plastic Surgery Complications: A Review for Emergency Clinicians10.5811/westjem.2020.6.46415 ↗
4. Psychological complications in 281 plastic surgery practices10.1097/00006534-199910000-00002 ↗
5. A brief overview and history of temporary fillers: Evolution, advantages, and limitations10.1097/01.prs.0000248788.97350.18 ↗
6. Global Aesthetics Consensus: Avoidance and Management of Complications from Hyaluronic Acid Fillers-Evidence- and Opinion-Based Review and Consensus Recommendations10.1097/PRS.0000000000002184 ↗
7. Injectable fillers for volume replacement in the aging face10.1055/s-0032-1305786 ↗
8. Vascular Complications after Facial Filler Injection: A Literature Review and Meta-analysis
9. Exploring Emotional Responses After Postoperative Complications: A Qualitative Study of Practicing Surgeons10.1097/SLA.0000000000004041 ↗
10. Effective e-learning for health professionals and students--barriers and their solutions. A systematic review of the literature--findings from the HeXL project10.1111/j.1470-3327.2005.00614.x ↗
11. A Systematic Review of Aesthetic Surgery Training Within Plastic Surgery Training Programs in the USA: An In-Depth Analysis and Practical Reference10.1007/s00266-021-02557-0 ↗
12. An effective and novel method for teaching applied facial anatomy and related procedural skills to esthetic physicians10.2147/AMEP.S181874 ↗
13. Ypinazar, V.A., and Margolis, S.A. (2006). Clinical simulators: Applications and implications for rural medical education. Rural Remote Health, 6.10.22605/RRH527 ↗
14. Low- to high-fidelity simulation—A continuum of medical education?10.1046/j.1365-2923.37.s1.9.x ↗
15. To the point: Medical education review of the role of simulators in surgical training10.1016/j.ajog.2008.05.002 ↗
16. Using clinical simulation to study how to improve quality and safety in healthcare10.1136/bmjstel-2018-000370 ↗
17. Changmin Seo Development and Usability of a Virtual Reality-Based Filler Injection Training System10.1007/s00266-020-01872-2 ↗
18. (2023, April 20). Digital Korean Human Information System for Better Project. Available online: https://dk.kisti.re.kr/.
19. Reproducibility of Facial Soft Tissue Thickness Measurements Using Cone-Beam CT Images According to the Measurement Methods10.1111/1556-4029.12766 ↗
20. Ultrasound Anatomy of the Dorsal Nasal Artery as it Relates to Liquid Rhinoplasty Procedures10.1016/j.fsc.2022.01.002 ↗
21. Three-Dimensional Computed Tomography Scanning of Temporal Vessels to Assess the Safety of Filler Injections10.1093/asj/sjaa371 ↗
22. Zygomatico-orbital artery: The largest artery in the temporal area10.1016/j.bjps.2017.10.003 ↗
23. Three-Dimensional Arterial Distribution Over the Midline of the Nasal Bone10.1093/asj/sjab432 ↗
24. Retrospective morphometric analysis of the infraorbital foramen with cone beam computed tomography10.4103/1119-3077.217247 ↗
25. Morphometric analysis of the infraorbital groove, canal, and foramen on three-dimensional reconstruction of computed tomography scans10.1007/s00276-013-1077-5 ↗
26. Anatomic evaluation of the normal variants of the arteries of face using color Doppler ultrasonography: Implications for facial aesthetic procedures10.1111/jocd.15646 ↗
27. Positional relationship of superior and inferior labial artery by ultrasonography image analysis for safe lip augmentation procedures10.1002/ca.23379 ↗
28. Lumen Diameter and Associated Anatomy of the Superior Labial Artery with a Clinical Application to Dermal Filler Injection10.1097/DSS.0000000000002074 ↗
29. Anatomical and Ultrasonography-Based Investigation to Localize the Arteries on the Central Forehead Region During the Glabellar Augmentation Procedure10.1002/ca.23516 ↗
30. Implication of Location of the Ascending Mental Artery at the Chin Injection Point10.1097/PRS.0000000000006394 ↗
31. Evaluation of facial artery course variations and depth by Doppler ultrasonography10.1111/jocd.13838 ↗
32. Soft tissue thickness estimation for head, face, and neck from CT data for product design purposes
33. Bargiela-Chiappini, F., and Haugh, M. (2009). Face Communication and Social Interaction, University of Toronto Press.10.3138/9781845537258 ↗
34. Kret, M.E. (2015). Emotional expressions beyond facial muscle actions. A call for studying autonomic signals and their impact on social perception. Front. Psychol., 6.10.3389/fpsyg.2015.00711 ↗
35. Do we need dissection in an integrated problem-based learning medical course? Perceptions of first- and second-year students10.1007/s00276-007-0180-x ↗
36. Potential health hazards for students exposed to formaldehyde in the gross anatomy laboratory
37. Simulation in medicine: Addressing patient safety and improving the interface between healthcare providers and medical technology10.2345/i0899-8205-40-5-399.1 ↗
38. Simulation-based medical education in clinical skills laboratory10.2152/jmi.59.28 ↗
39. Simulation training improves clinical knowledge of major haemorrhage management in foundation year doctors10.1111/tme.12161 ↗
40. The utility of simulation in medical education: What is the evidence?10.1002/msj.20127 ↗
41. Simulation in preparation or substitution for clinical placement: A systematic review of the literature
42. Sørensen, J.L., Østergaard, D., LeBlanc, V., Ottesen, B., Konge, L., and Van der Vleuten, C. (2017). Design of simulation-based medical education and advantages and disadvantages of in situ simulation versus off-site simulation. BMC Med. Educ., 17.10.1186/s12909-016-0838-3 ↗
43. Mussi, E., Furferi, R., Volpe, Y., Facchini, F., McGreevy, K.S., and Uccheddu, F. (2019). Ear Reconstruction Simulation: From Handcrafting to 3D Printing. Bioengineering, 6.10.3390/bioengineering6010014 ↗
44. Krogman, W.M. (1986). The Human Skeleton in Forensic Medicine, Charles C Thomas. [2nd ed.].
45. Matsumura, H., Tanijiri, T., Kouchi, M., Hanihara, T., Friess, M., Moiseyev, V., and Stringer, C. (2022). Global patterns of the cranial form of modern human populations described by analysis of a 3D surface homologous model. Sci. Rep., 12.10.1038/s41598-022-15883-3 ↗
46. Facial soft tissue depths in craniofacial identification (part I): An analytical review of the published adult data10.1111/j.1556-4029.2008.00852.x ↗
47. Pros and cons of simulation in medical education: A review