An Ambiguity in Child Body Surface Area Measurement
Source abstract
Abstract
Body Surface Area (BSA) and Total Body Surface Area (TBSA) are important indicators used in different domains of medicine, playing a crucial role in oncology, toxicology, and even transplantology or cardiology. Their main (although not sole) use in medicine is to dose medications according to the patient’s BSA/TBSA. Other fields where BSA is commonly employed include the treatment of burns—the fluid doses are according to Parkland’s rule, which is based on BSA estimation. Thus, a proper estimation of BSA value directly influences the patient’s chances of survival—one can easily imagine the consequences of not administering enough fluids in the critical phase of a burned patient’s management. In medical practice, even small deviations in the estimated BSA value may have a significant impact on the patient’s treatment process and, in extreme cases, lead to their death. This problem is particularly important in the treatment of children and adolescents. The aim of our article is to present the most popular formulae used to estimate the BSA value for children in the case of minors and to discuss discrepancies between them. In the case of a 4-week-old neonate, the smallest difference in maximum BSA calculation discrepancies amounts up to 0.22 m2, which corresponds to roughly 80% of the typical BSA value for this age group, while for 12-year-old patients this parameter is 0.15 m2, equalling about 11% of the standard BSA value for this age category. The maximum deviation between the patterns reaches 0.28 m2 for 4-week-olds and over 0.75 m2 for 12-year-old children. These notable discrepancies in BSA calculations highlight the necessity for more precise and dependable methods, particularly when dealing with paediatric patients.
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Research context
OpenAlex topics: Burn Injury Management and Outcomes · Body Composition Measurement Techniques · Hemodynamic Monitoring and Therapy
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Applied Physics and Mathematics, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland
Faculty of Electrical and Control Engineering, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland
Faculty of Health Sciences, Medical University of Gdańsk, M. Skłodowskiej-Curie Street 3a, 80-210 Gdansk, Poland
University Clinical Centre in Gdansk, Medical University of Gdansk, Dębinki 7, 80-952 Gdansk, Poland
References (57)
Show source-provided references
1. Ovarian cancer survival and chemotherapy dosing, body mass index, and body surface area: Are we there yet?10.1001/jamaoncol.2015.1926 ↗
2. Comparison of body mass index and body surface area as outcome predictors in patients with systolic heart failure10.5603/CJ.a2014.0104 ↗
3. Misleading indexed hemodynamic parameters: The clinical importance of discordant BMI and BSA at extremes of weight10.1186/cc11876 ↗
4. A formula to estimate the approximate surface area if height and weight be known
5. Redlarski, G., Palkowski, A., and Krawczuk, M. (2016). Body surface area formulae: An alarming ambiguity. Sci. Rep., 6.10.1038/srep27966 ↗
6. Estimation of Total Body Surface Area Burned: A Comparison Between Burn Unit and Referring Facilities
7. Thelwell, M., Masters, N., Appleyard, R., and Bullas, A.M. (2024). Advanced Body Measurement Techniques Can Complement Current Methods of Cytotoxic Chemotherapy Dose Prescription. Appl. Sci., 14.10.3390/app14020834 ↗
8. Wu, Q., Zhou, Y., Fan, X., Ma, H., Gu, W., and Sun, F. (2022). Evaluation of nine formulas for estimating the body surface area of children with hematological malignancies. Front. Pediatr., 10.10.3389/fped.2022.989049 ↗
9. Pediatric Dose Calculation Issues and the Need for Human Factors–Informed Preventative Technology Optimizations10.33940/data/2022.6.5 ↗
10. Flint, B., Das, J.M., and Hall, C.A. (2025). Body Surface Area, StatPearls Publishing. StatPearls [Internet].
11. Estimation of body surface area in neonates, infants, and children using body weight alone10.1016/j.ijpam.2020.09.003 ↗
12. Alvear-Vasquez, F., Vidal-Espinoza, R., Gomez-Campos, R., de Campos, L.F.C.C., Lazari, E., Guzmán-Luján, J.F., Pablos-Monzó, A., and Cossio-Bolaños, M. (2023). Body surface area is a predictor of maturity status in school children and adolescents. BMC Pediatr., 23.10.1186/s12887-023-04222-8 ↗
13. Piecuch, M., Chylak, M., Górski, M., Garbicz-Kata, J., Szczyrba, A., Buczkowska, M., Malinowska-Borowska, J., Nowak, J.U., Niedziela, J.T., and Gąsior, M. (2024). Comparison of the Effectiveness of Body Surface Area Estimation Formulas in Predicting the Risk of Death in Patients with Heart Failure. J. Clin. Med., 13.10.20944/preprints202410.0678.v1 ↗
14. Oberflächenmessungen des menschlichen Körpers
15. Studies on the physical surface area of Japanese: Part 18 calculation formulas in three stages over all ages10.1265/jjh.23.443 ↗
16. Über Oberflächenmessungen an Säuglingen und ihre Bedeutung für den Nahrungsbedarf
17. A simple empirical formula for calculating approximate surface area in children10.1136/adc.41.220.681 ↗
18. Boyd, E. (1935). The Growth of the Surface Area of the Human Body, University Minnesota Press.
19. Geometric method for measuring body surface area: A height-weight formula validated in infants, children, and adults10.1016/S0022-3476(78)80601-5 ↗
20. The body surface area of Saudi newborns
21. Die natürliche Ernährung eines Säuglings
22. Determination of body surface area in Indian Hindu children10.1152/jappl.1961.16.6.969 ↗
23. The surface area and volume of the human fetus
24. Simplified calculation of body surface area10.1056/NEJM198710223171717 ↗
25. Behrman, R.E., and Vaughan, V.C. (1987). Developmental pediatrics: Assessment of growth and development. Nelson Textbook of Pediatrics, WB Saunders.
26. A linear equation for estimating the body surface area in infants and children
27. (2025, November 08). The WHO Child Growth Standards. (n.d.). Available online: https://www.who.int/tools/child-growth-standards/standards.
28. Changes in state-specific childhood obesity and overweight prevalence in the United States from 2003 to 200710.1001/archpediatrics.2010.84 ↗
29. Worldwide trends in childhood overweight and obesity10.1080/17477160600586747 ↗
30. Childhood obesity and overweight prevalence trends in England: Evidence for growing socioeconomic disparities10.1038/ijo.2009.217 ↗
31. Anthropometric measurements of the body composition of cancer patients determine the precise role of the body surface area and the calculation of the dose of chemotherapy
32. How to calculate the dose of chemotherapy10.1038/sj.bjc.6600139 ↗
33. Dose banding as an alternative to body surface area-based dosing of chemotherapeutic agents10.1038/bjc.2012.357 ↗
34. Determination of the safe range of graft size mismatch using body surface area index in deceased liver transplantation10.1111/tri.12111 ↗
35. Calculation of child and adult standard liver volume for liver transplantation10.1002/hep.1840210515 ↗
36. Pharmacology and toxicology of infant skin10.1111/1523-1747.ep12525553 ↗
37. Topical treatment of psoriasis: Questionnaire results on topical therapy accessibility and influence of body surface area on usage10.1111/jdv.14250 ↗
38. Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis: The advantage of a picture-based tool10.1111/jdv.15726 ↗
39. Weight or body surface area dosing of steroids in nephrotic syndrome: Is there an outcome difference?10.1007/s00467-011-1961-3 ↗
40. Research priorities for burn nursing: Rehabilitation, discharge planning, and follow-up care10.1097/00004630-199207000-00017 ↗
41. The potential impact of wrong TBSA estimations on fluid resuscitation in patients suffering from burns: Things to keep in mind10.1016/j.burns.2013.06.019 ↗
42. Comparison of transepidermal water loss (TEWL) measurements with two novel sensors based on different sensing principles10.1016/j.sna.2007.04.012 ↗
43. Health-risk assessment for workers exposed to polycyclic aromatic hydrocarbons (PAHs) in a carbon black manufacturing industry10.1016/S0048-9697(01)00643-X ↗
44. Udristioiu, A., Nanu, M., Nanu, C., Udristioiu, I., Popescu, F., and Galescu, L. (2012). Variability of biological parameters in blood samples between two consecutive schedules of hemodialysis. Basic Nephrology and Acute Kidney Injury, InTech.10.5772/26938 ↗
45. Starship Children’s Health (2024, March 15). Wilms Tumour PI Wilms 1 Protocol. Available online: https://starship.org.nz/guidelines/wilms-tumour-pi-wilms-1-protocol/.
46. Current treatment for Wilms tumor: COG and SIOP standards10.1136/wjps-2019-000038 ↗
47. Treatment of stage IV favorable histology Wilms tumor with lung metastases: A report from the Children’s Oncology Group AREN0533 study10.1200/JCO.2017.77.1931 ↗
48. Contemporary management of retinoblastoma in the context of a low-resource country10.4103/npmj.npmj_21_19 ↗
49. Modern treatment of retinoblastoma: A 2020 review10.4103/ijo.IJO_721_20 ↗
50. Interval compressed vincristine, doxorubicin, cyclophosphamide alternating with ifosfamide, etoposide in patients with advanced Ewing’s and other small round cell sarcomas10.1186/2045-3329-2-12 ↗
51. Combination chemotherapy consisting of irinotecan, etoposide, and carboplatin for refractory or relapsed neuroblastoma10.1002/cam4.4529 ↗
52. Pediatric high-risk neuroblastoma with autologous stem cell transplant—20 years of experience10.1016/j.ijpam.2021.02.006 ↗
53. Mercaptopurine/methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: Clinical facts and fiction10.1097/MPH.0000000000000206 ↗
54. National Comprehensive Cancer Network (2025, November 08). Acute Lymphoblastic Leukemia. Available online: https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1410.
55. Characteristics of pediatric chemotherapy medication errors in a national error reporting database10.1002/cncr.22742 ↗
56. Obesity and the skin: Skin physiology and skin manifestations of obesity10.1016/j.jaad.2006.12.004 ↗
57. An improvement of body surface area formulas using the 3D scanning technique10.13075/ijomeh.1896.02356 ↗