Plane Wave Imaging with Large-Scale 2D Sparse Arrays: A Method for Near-Field Enhancement via Aperture Diversity
Source abstract
Abstract
In the context of a medical imaging application for preclinical research, specifically cerebrovascular imaging in small animals, this work addresses the challenges associated with using a large-scale 2D ultrasonic array comprising 32×32 elements (96λ×96λ ). The application imposes stringent requirements: operation in the extreme near field, high spatial resolution, high frequency, high frame rate, and imaging within a highly attenuating medium. These demands, combined with current technological limitations, such as element size and constraints on the number of channels that can be driven in parallel, present significant challenges for system design and implementation. To assess system performance, plane wave imaging is employed as a reference modality due to its ability to meet high acquisition speed requirements. Our analysis reveals limitations in spatial coverage and image quality when operating the full aperture under plane wave transmission constraints. To address these limitations, we propose a sparse aperture strategy. When combined with advanced signal processing techniques, this approach enhances both contrast and resolution while preserving acquisition speed, making it a promising solution for high-performance ultrasonic imaging under the demanding conditions of preclinical research.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Antenna Design and Optimization · Ultrasonics and Acoustic Wave Propagation · Ultrasound Imaging and Elastography
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Instituto de Tecnologías Físicas y de la Información (ITEFI), Consejo Superior de Investigaciones Científicas (CSIC), 28006 Madrid, Spain
Funding
Recovery, Transformation and Resilience Plan through the European Union’s Next Generation funds · European Commission–NextGenerationEU, through Momentum CSIC Programme: Develop Your Digital Talent · Community of Madrid through the R&D activities program in technologies
References (30)
Show source-provided references
1. 3D ultrafast Doppler imaging applied to the noninvasive mapping of blood vessels in vivo
2. Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging10.1038/nature16066 ↗
3. 3D Transcranial Ultrasound Localization Microscopy in the Rat Brain with a Multiplexed Matrix Probe10.1109/TBME.2021.3137265 ↗
4. Simultaneous positron emission tomography and ultrafast ultrasound for hybrid molecular, anatomical and functional imaging10.1038/s41551-018-0188-z ↗
5. Evaluation of tumor microvasculature with 3D ultrasound localization microscopy based on 2D matrix array10.1007/s00330-023-10039-x ↗
6. 3-D Transcranial Ultrasound Localization Microscopy Reveals Major Arteries in the Sheep Brain10.1109/TUFFC.2024.3432998 ↗
7. Whole Organ Volumetric Sensing Ultrasound Localization Microscopy for Characterization of Kidney Structure10.1109/TMI.2024.3411669 ↗
8. Li, X., Gachagan, A., and Murray, P. (2020). Design of 2D Sparse Array Transducers for Anomaly Detection in Medical Phantoms. Sensors, 20.10.3390/s20185370 ↗
9. Martínez-Graullera, Ó, de Souza, J.C.E., Parrilla Romero, M., and Higuti, R.T. (2021). Design of 2D Planar Sparse Binned Arrays Based on the Coarray Analysis. Sensors, 21.10.3390/s21238018 ↗
10. Unfocused Field Analysis of a Density-Tapered Spiral Array for High-Volume-Rate 3-D Ultrasound Imaging10.1109/TUFFC.2022.3188245 ↗
11. Skull-Mimicking Phantoms with Tunable Properties for Transcranial Ultrasound Imaging10.1109/ACCESS.2025.3566388 ↗
12. Coherent plane-wave compounding for very high frame rate ultrasonography and transient elastography10.1109/TUFFC.2009.1067 ↗
13. Simulation, Design and characterization of a Large Divergent Element Sparse Array (LDESA) for 3D Ultrasound Imaging10.1109/TUFFC.2025.3583178 ↗
14. Ultrafast 3D Ultrasound Localization Microscopy Using a 32 × 32 Matrix Array10.1109/TMI.2018.2890358 ↗
15. Non-invasive 4D transcranial functional ultrasound and ultrasound localization microscopy for multimodal imaging of neurovascular response10.1038/s41598-024-81243-y ↗
16. Ultrafast imaging in biomedical ultrasound10.1109/TUFFC.2014.2882 ↗
17. Functional Ultrasound Neuroimaging10.1146/annurev-neuro-111020-100706 ↗
18. Koo, S., Jang, D., Yu, J., and Yoon, H. (2025). Sub-pitch plane-wave imaging for improved 3-D ultrasound imaging with a large pitch 2-D array. Biomed. Eng. Lett.10.1007/s13534-025-00500-9 ↗
19. Identification of brain structures and blood vessels by conventional ultrasound in rats10.1016/j.jneumeth.2020.108935 ↗
20. 3-D Super-Resolution Ultrasound Imaging with a 2-D Sparse Array10.1109/TUFFC.2019.2943646 ↗
21. A Platform for Brain-wide Volumetric Functional Ultrasound Imaging and Analysis of Circuit Dynamics in Awake Mice10.1016/j.neuron.2020.09.020 ↗
22. A new approach to calculate the field radiated from arbitrarily structured transducer arrays10.1109/58.753032 ↗
23. A note on the calculation and interpretation of the Gini coefficient10.1016/0165-1765(84)90126-5 ↗
24. Una nota sobre el cálculo del índice de Gini
25. Fritsch, C., Sánchez, T., Anaya, J.J., Ibañez, A., Ullate, L.G., Parrilla, M., and Izquierdo, M.A.G. (1995, January 7–10). A pipelined architecture for high speed automated NDE. Proceedings of the 1995 IEEE Ultrasonics Symposium. Proceedings. An International Symposium, Seattle, WA, USA.
26. Yang, J., Li, J., Chen, X., Xi, J., Cai, H., and Wang, Y. (2021). Cross Subaperture Averaging Generalized Sidelobe Canceler Beamforming Applied to Medical Ultrasound Imaging. Appl. Sci., 11.10.3390/app11188689 ↗
27. Shen, C.-C., and Hsieh, P.-Y. (2019). Two-Dimensional Spatial Coherence for Ultrasonic DMAS Beamforming in Multi-Angle Plane-Wave Imaging. Appl. Sci., 9.10.3390/app9193973 ↗
28. Yagüe-Jiménez, V., Ibáñez Rodríguez, A., Parrilla Romero, M., and Martínez-Graullera, O. (2020). Rician Beamforming: Despeckle Method via Coarray Projection Stochastic Analysis. Appl. Sci., 10.10.3390/app10030847 ↗
29. Nili, V.A., Kavehvash, Z., Mostafavi, S.M., Shabany, M., and Mehrmohammadi, M. (IEEE Sens. J., 2025). Structured Illumination for Super-Resolution Synthetic Aperture Ultrasound Imaging, IEEE Sens. J., early access.10.1109/JSEN.2025.3604382 ↗
30. 3D f-k migration beamformer for full matrix ultrasound imaging using row-column-addressed array10.1016/j.ultras.2025.107809 ↗