journal article·2025-09-17Open access

Evaluation of the Effectiveness of a Postbiotic in Home Care Maintenance in Patients Affected by Peri-Implant Mucositis

Silvia Sabatini, Carlos Perez-Albacete Martinez, Jessica Bassignani, Carolina Maiorani, Andrea Butera, Andrea Scribante

Applied Sciences· Volume 15· Issue 18

Abstract

Peri-implant mucositis is an inflammatory condition that affects the peri-implant mucosa, without bone involvement. Peri-implant mucositis can include erythema, swelling, and bleeding, and the mucosa can be painful even with the traditional oral hygiene procedures. Peri-implant mucositis is always a reversible condition but, if left untreated, it can degenerate into peri-implantitis. Although biofilm control is considered the gold-standard therapy, some adjunctive therapies can be employed. The aim of this study is to investigate the efficacy of postbiotics in peri-implant mucositis management. Forty patients in good systemic health with at least one implant diagnosed with peri-implant mucositis were enrolled in this case–control study. The control group received professional biofilm removal and home care instructions, while the test group was also asked to use a postbiotic gel. Clinical indices of inflammation, such as probing pocket depth (PPD), plaque index (PI), bleeding on probing (BoP), erythema, pain, suppuration and swelling, were collected at four timepoints during observation and analyzed at both the patient and site levels. After one year, clinical indices statistically significantly improved in both groups compared to baseline. The test group showed greater reductions. PPD was statistically significantly lower at the site level in the test group than in the control group. The results of this study confirm that biofilm control is an effective therapy for peri-implant mucositis. Our findings showed that postbiotics used as an adjunctive in home therapy have been effective in managing clinical indices in patients with peri-implant mucositis.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Dental Implant Techniques and Outcomes · Oral health in cancer treatment · Scientific and Engineering Research Topics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy

Health Sciences PhD Program, Universidad Catòlica de Murcia UCAM, Campus de Ios Jerònimos N. 135, 30107 Guadalupe, Murcia, Spain

Tissue Regeneration and Repair Group, Biomaterials and Tissue Engineering, Faculty of Health Sciences, UCAM-Universidad Catòlica San Antonio de Murcia, 30107 Guadalupe, Murcia, Spain

EIMS (European Institute for Medical Studies), HEI (Higher Education Institution), St George’s Business Complex, Elija Zammit Street, STJ3150 St. Julian’s, Malta

Unit of Dental Hygiene, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy

Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy

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