Studies and Rejection of Intercrystal Crosstalk on FPGA in a High-Energy Photon-Counting System
Source abstract
Abstract
Intercrystal scatter reduces system sensitivity and spatial resolution, a phenomenon that has been extensively studied in positron emission tomography (PET) systems. However, the issue is even more significant in high-energy systems. The purpose of this study is to propose a practical crosstalk rejection technique and demonstrate its applicability in high-energy photon-counting systems. The effect of inter-crystal scattering interactions between 60Co γ photons and lutetium yttrium oxyorthosilicate (LYSO) scintillator crystals is investigated through Monte Carlo simulations conducted using the Geant4 toolkit. To suppress the crosstalk phenomenon, a field-programmable gate array (FPGA)-based algorithm is proposed to suppress inter-crystal scattering events, characterized by a time window of 5 nanoseconds and detector window sizes of one or two. The 250 mm Fe steel penetration model is used to evaluate the proposed algorithm, showing improved radiation image quality, particularly with a detector window size of two, which performs better under low-count-rate conditions. Laboratory testing indicates that the proposed algorithm can enhance steel penetration (SP) by 60–70 mm of Fe when compared to the existing current integration system under the same settings. The suggested method has been proven effective in producing higher-quality images and demonstrates good adaptability by adapting the detector window width according to different system count rates.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Medical Imaging Techniques and Applications · Radiation Detection and Scintillator Technologies · Radiation Therapy and Dosimetry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Nuclear Energy and New Energy Technology, Tsinghua University, Beijing 100084, China
Beijing Key Laboratory on Nuclear Detection & Measurement Technology, Beijing 100084, China
China Institute of Nuclear Industry Strategy, Beijing 100084, China
Hefei Meyer Optoelectronic Technology Inc., Hefei 230088, China
References (28)
Show source-provided references
1. Photon Counting Detectors: Concept, Technical Challenges, and Clinical Outlook10.1016/j.ejrad.2022.110229 ↗
2. Photon-Counting CT Systems: A Technical Review of Current Clinical Possibilities10.1016/j.diii.2024.09.002 ↗
3. Self-Powered Perovskite Photon-Counting Detectors10.1038/s41586-023-05847-6 ↗
4. Intercrystal Optical Crosstalk in Radiation Detectors: Monte Carlo Modeling and Experimental Validation10.1109/TRPMS.2024.3395131 ↗
5. Object and Detector Scatter-Function Dependence on Energy and Position in High Resolution PET10.1109/23.467732 ↗
6. Compton Scatter and X-Ray Crosstalk and the Use of Very Thin Intercrystal Septa in High-Resolution PET Detectors10.1109/23.568809 ↗
7. A DOI Detector with Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging10.1109/TNS.2015.2408333 ↗
8. Impact of Intercrystal Crosstalk on Depth-of-Interaction Information in PET Detectors10.1109/TNS.2007.895508 ↗
9. Stickel, J.R., and Cherry, S.R. (2004). High-Resolution PET Detector Design: Modelling Components of Intrinsic Spatial Resolution. Phys. Med. Biol., 50.10.1088/0031-9155/50/2/001 ↗
10. Inter-Crystal Scatter in a Dual Layer, High Resolution LSO-APD Positron Emission Tomograph10.1088/0031-9155/48/7/302 ↗
11. Effects of Intercrystal Crosstalk on Multielement LSO/APD PET Detectors10.1109/TNS.2003.812452 ↗
12. Zeraatkar, N., Ay, M.R., Sarkar, S., Geramifar, P., and Rahmim, A. (November, January 30). Quantitative Investigation of Inter-Crystal Scatter and Penetration in the GE Discovery RX PET/CT Scanner Using Monte Carlo Simulations. Proceedings of the IEEE Nuclear Science Symposium & Medical Imaging Conference, Knoxville, TN, USA.
13. Kang, H.G., Nishikido, F., and Yamaya, T. (2021). A Staggered 3-Layer DOI PET Detector Using BaSO4 Reflector for Enhanced Crystal Identification and Inter-Crystal Scattering Event Discrimination Capability. Biomed. Phys. Eng. Express, 7.10.1088/2057-1976/abf6a8 ↗
14. Teimoorisichani, M., and Goertzen, A.L. (2019). A Study of Inter-Crystal Scatter in Dual-Layer Offset Scintillator Arrays for Brain-Dedicated PET Scanners. Phys. Med. Biol., 64.10.1088/1361-6560/ab1503 ↗
15. Park, S.-J., Rogers, W.L., and Clinthorne, N.H. (2003, January 19–25). Effect of Intercrystal Compton Scatter on Efficiency and Image Noise in Small Animal PET Module. Proceedings of the 2003 IEEE Nuclear Science Symposium. Conference Record, Portland, OR, USA.
16. Rafecas, M., Boning, G., Pichler, B.J., Lorenz, E., Schwaiger, M., and Ziegler, S.I. (2001, January 4–10). Characterization and Processing of Inter-Crystal Scatter in a Dual Layer, High Resolution LSO-APD-PET. Proceedings of the 2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310), San Diego, CA, USA.
17. Xu, H., Lenz, M., Caldeira, L., Ma, B., Pietrzyk, U., Lerche, C., Shah, N.J., and Scheins, J. (2019). Resolution Modeling in Projection Space Using a Factorized Multi-Block Detector Response Function for PET Image Reconstruction. Phys. Med. Biol., 64.10.1088/1361-6560/ab266b ↗
18. Maximum Likelihood Positioning Algorithm for High-Resolution PET Scanners10.1118/1.4950719 ↗
19. Yoshida, E., Obata, F., and Yamaya, T. (2024). Optical Crosstalk of Protective Cover on MPPC Array for TOF PET Detector. Phys. Med. Biol., 69.10.1088/1361-6560/ad5268 ↗
20. Physical Design of Photon-Counting Mode γ-Ray Large Object Radiation Imaging System
21. High-Dose Rate Detection System for Gamma and X Radiation Using Scattered Gamma Rays10.1016/j.radmeas.2023.106912 ↗
22. Ni, M., Li, G., and Wang, Z. (2020, January 4–5). Study on Scattering Correction of the 60Co Gantry-Movable Dual-Projection Digital Radiography Inspection System. Proceedings of the 2020 International Conference on Nuclear Engineering collocated with the ASME 2020 Power Conference, Virtual.10.1115/1.0000306V ↗
23. Thien, T.C., and Nemallapudi, M.V. (2024). Determination of Lutetium Density in LYSO Crystals: Methodology and PET Detector Applications. Phys. Med. Biol., 69.10.1088/1361-6560/ad2e6e ↗
24. Recent Developments in GEANT410.1016/j.nima.2016.06.125 ↗
25. Design of a Nanosecond Voltage Comparator with PECL Logic for a Photon-Counting Radiation Imaging System Application10.1155/2023/6810882 ↗
26. An, J., Wu, Z., Zhou, L., Liu, Y., Xiang, X., Wang, L., and Wu, H. (2000). Isotope Radiography for Container Inspection. Isotope Production and Applications in the 21st Century, World Scientific.10.1142/9789812793867_0035 ↗
27. Image Quality Indicator Localization Using Mask R-CNN
28. David Hsu, F.C., David Freese, L., Derek Innes, R., and Craig Levin, S. (2017, January 21–28). Intercrystal Scatter Studies for a Clinical PET System with 1mm3 Resolution 3D Position Sensitive Scintillation Detectors. Proceedings of the 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Atlanta, GA, USA.10.1109/NSSMIC.2017.8532780 ↗