Dynamic Alternations in Mother–Infant Dyad’s Gut Microbiota over the Period of Six Months
Source abstract
Abstract
Since birth, the human microbiome plays a pivotal role in health. It is intriguing to understand the establishing roles of intestinal microbiota in infants. This study aimed to investigate the dynamic changes in maternal and infant gut microbiota, the interaction between intestinal microbiota, and the function of intestinal microbiota. This study recruited one pregnant woman >35 weeks gestational age. Faeces of the mother–infant dyad were regularly collected until the infant was six months old for metagenomic analysis. The results showed that the infant’s gut microbiota was significantly different from the mother’s, encompassing Bacteroides fragilis, Ruminococcus gnavus, Klebsiella pneumoniae, and Klebsiella michiganensis. Infant- or mother-specific differential metabolic pathways were found between the mother and infant’s gut microbiome, implicating differences in the intestinal metagenomic potential/function. In conclusion, the gut microbes and functions were gradually established as the infant grew.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Gut microbiota and health · Diet and metabolism studies · Birth, Development, and Health
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China
Key Laboratory of Dairy Products Processing, Ministry of Agriculture and Rural Affairs, Inner Mongolia Agricultural University, Hohhot 010018, China
Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China
Funding
Inner Mongolia Agricultural University high-level/excellent doctoral talent introduction research project · University Basic Scientific Research Business Expenses Project—Young Teachers Research Ability Enhancement Fund Project, 2023 Financial Funds · Discipline Project of College of Veterinary Medicine, Inner Mongolia Agricultural University
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