The Prevalence and Clinical Implications of Atlantal Posterior Arch Defects: A CBCT Analysis of 500 Italian Patients
Source abstract
Abstract
Atlas Posterior Arch Deficiency (APAD) is a rare anatomical variation of the atlas vertebra detected using cone-beam computed tomography (CBCT). This study assessed the prevalence, classification, and clinical implications of APAD in an Italian cohort. Methods: We analyzed CBCT images from 500 Italian patients (17–60 years) from the University “G. D’Annunzio” in Chieti. The sample was evenly split between genders. The sample was evenly split between genders. APAD classification was performed, identifying five morphological types. Imaging used a low-dose protocol with a Pax-Zenith 3D CBCT machine and Dolphin imaging software (12.0.9.58). Results: APAD was identified in thirteen patients—twelve with partial APAD and one with complete APAD. Two cases also had Ponticulus Posticus. Type A anomalies were most common; no cases of types B, C, D, or E were observed. None of the cases were symptomatic. Conclusions: APAD is rare in this cohort, with partial forms being the most frequent. CBCT is effective for diagnosing APAD, highlighting the importance of routine imaging in orthodontic assessments. Despite the absence of symptoms, awareness and monitoring for potential symptoms are important. Further research is needed to understand APAD’s clinical significance across different populations.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Spinal Fractures and Fixation Techniques · Shoulder and Clavicle Injuries · Spine and Intervertebral Disc Pathology
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Innovative Technologies in Medicine & Dentistry, University “G. D’Annunzio” of Chieti-Pescara, 66100 Chieti, Italy
Department of Dental Health, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia
Department of Anatomic, Histologic, Medical-Legal Sciences and of Locomotor System, Rome University Sapienza, 00185 Rome, Italy
References (27)
Show source-provided references
1. Pasini, M., Giuca, M.R., Ligori, S., Mummolo, S., Fiasca, F., Marzo, G., and Quinzi, V. (2020). Association between Anatomical Variations and maxillary canine impaction: A retrospective study in orthodontics. Appl. Sci., 10.10.3390/app10165638 ↗
2. Multidisciplinary approach to the craniovertebral junction. Historical insights, current and future perspectives in the neurosurgical and otorhinolaryngological alliance10.14639/0392-100X-suppl.1-41-2021-05 ↗
3. Imaging of cranio-cervical junction traumas10.1016/j.ejrad.2020.108960 ↗
4. Complete absence of the posterior arch of C1: Case report10.4103/0974-8237.147090 ↗
5. Sex-specific differences in ossification patterns of the atlas and axis: A computed tomography study10.1007/s12519-022-00523-7 ↗
6. Congenital defects of the posterior arch of the atlas: A report of seven cases including an affected mother and son
7. Congenital cleft of anterior arch and partial aplasia of the posterior arch of the c110.3340/jkns.2011.49.3.178 ↗
8. Congenital partial aplasia of the posterior arch of the atlas causing myelopathy: Case report and review of the literature10.1097/01.BRS.0000065492.85852.A9 ↗
9. The prevalence of congenital C1 arch anomalies10.1007/s00586-017-5283-4 ↗
10. Congenital C1 arch deficiency: Grand Round presentation10.1007/s00586-013-2682-z ↗
11. Macrì, M., Perrella, G., Varvara, G., Murmura, G., Traini, T., Rendina, F., and Festa, F. (2021). Assessments of Prevalence of Ponticulus Posticus, Atlas Posterior Arch Deficiency, Sella Turcica Bridging, Maxillary Canine Impaction, and Associations Among Them in 500 CBCTs of Italian Orthodontic Patients. Front. Dent. Med., 2.10.3389/fdmed.2021.708169 ↗
12. Agenesis of the posterior arch of the atlas10.1590/S0041-87812002000200005 ↗
13. Aplasia of the posterior arch of the atlas: A proposal for a new clinical classification
14. Hypoplasia of C1’s posterior arch: Is there an ideal anatomical classification?10.25259/SNI_820_2021 ↗
15. Hypertrophy of the anterior arch of the atlas associated with congenital nonunion of the posterior arch: A retrospective case-control study10.1016/j.spinee.2013.07.482 ↗
16. Congenital defect of the posterior arch of C1: A case report10.21037/jss-20-628 ↗
17. Cervical myelopathy caused by atlantoaxial instability in a patient with an os odontoideum and total aplasia of the posterior arch of the atlas: A case report10.1186/1752-1947-6-171 ↗
18. Cervical myelopathy associated with congenital C2/3 canal stenosis and deficiencies of the posterior arch of the atlas and laminae of the axis: Case report and review of the literature10.1097/BRS.0b013e3181b64f0a ↗
19. Congenital absence of the posterior arch of the atlas—A strange but benign anomaly10.5704/MOJ.0711.007 ↗
20. Congenital hypoplasia of the posterior arch of the atlas: Case report and extensive review of the literature
21. Incidental findings in dental radiology are concerning for family doctors10.1515/med-2019-0050 ↗
22. The frequency and clinical significance of congenital defects of the posterior and anterior arch of the atlas10.3171/SPI-07/10/399 ↗
23. Ponticulus posticus on the posterior arch of atlas, prevalence analysis in symptomatic and asymptomatic patients of Gulbarga population
24. Congenital anterior midline cleft of the atlas and posterior atlanto-occipital fusion associated with symptomatic anterior atlantoaxial subluxation10.1007/s00590-012-1011-2 ↗
25. Congenital posterior arch defect of the atlas: Report of a rare anomaly
26. Anatomical variant of atlas: Arcuate foramen, occpitalization of atlas, and defect of posterior arch of atlas10.3340/jkns.2015.58.6.528 ↗
27. Macrì, M., Rendina, F., Feragalli, B., Pegreffi, F., and Festa, F. (2023). Prevalence of ponticulus posticus and migraine in 220 orthodontic patients: A cross-sectional study. Biology, 12.10.3390/biology12030471 ↗