Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats with MetS Induced with 30% Sucrose
Source abstract
Abstract
Pomegranate juice possesses therapeutic properties against metabolic syndrome. Microencapsulation of pomegranate juice (MPJ) may extend its shelf life; however, further research is necessary to ascertain its comparative efficacy with fresh juice. This work evaluated the effect of MPJ in an animal model with induced metabolic syndrome (MetS). MetS was induced in Male Wistar rats by administering 30% sucrose orally for 22 weeks. Once MetS was verified in the animals, seven groups were formed as follows: control (Ctrl); MetS; MetS + Placebo; Ctrl + MPJ; MetS + MPJ1 600; MetS + MPJ2 1800; and MetS + MPJ3 2900 mg/kg. Systolic and diastolic blood pressure, glucose, triglycerides, and total HDL-c levels in the MetS + MPJ groups improved significantly (p < 0.05) vs. the MetS group at the end of the study. Microencapsulation maintained the anti-metabolic-syndrome properties of pomegranate juice and could be used to control metabolic syndrome.
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Research context
OpenAlex topics: Pomegranate: compositions and health benefits · Pharmacology and Obesity Treatment · Phytochemicals and Antioxidant Activities
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Academic Area of Nursing, Graduate School of Tlahuelilpan, Autonomous University of Hidalgo State, Tlahuelilpan P.O. Box 42780, Hidalgo, Mexico
Departament of Microbiology, National School of Biological Sciences, National Polytechnic Institute, Mexico City P.O. Box 11340, Mexico
Division of Life Sciences, Nursing and Obstetrics Department, Campus Irapuato-Salamanca, Guanajuato University, Guanajuato P.O. Box 36612, Mexico
Academic Area of Pharmacy, Health Sciences Institute, Autonomous University of Hidalgo State, San Agustín Tlaxiaca P.O. Box 42160, Hidalgo, Mexico
Institute of Agricultural Sciences, Autonomous University of Hidalgo State, Tulancingo de Bravo P.O. Box 11340, Hidalgo, Mexico
Department of Animal Nutrition and Biochemistry, Faculty of Veterinary Medicine and Animal Science, National Autonomous University of Mexico, Mexico City 04510, Mexico
Academic Area of Medicine, Health Sciences Institute, Autonomous University of Hidalgo State, San Agustín Tlaxiaca P.O. Box 42160, Hidalgo, Mexico
Dale Bumpers National Rice Research Center, Stuttgart, AR P.O. Box 72160, USA
Academic Area of Nutrition, Health Sciences Institute, Autonomous University of Hidalgo State, San Agustín Tlaxiaca P.O. Box 42160, Hidalgo, Mexico
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