Volumetric Analysis of Aortic Changes after TEVAR Using Three-Dimensional Virtual Modeling
Source abstract
Abstract
TEVAR (thoracic endovascular aortic repair) is the preferred approach for treating descending thoracic aortic aneurysm (DTAA). After the procedure, patients require lifelong CTA (computed tomography angiography) follow-up to monitor the aorta’s remodeling process and the possible development of associated complications. With CTA, the aorta is usually measured with maximum diameters taken at specific locations, and even in experienced centers, this type of evaluation is prone to inter-observer variability. We introduce a new volumetric analysis of aortic changes after TEVAR using three-dimensional (3D) anatomical models. We applied the volumetric analysis to 24 patients who underwent TEVAR for DTAA. For each patient, the descending thoracic aorta was evaluated using both the maximum diameter from CTA and the volume from 3D reconstructions, at discharge and 12 months after TEVAR. Both volume and diameter evaluations were then related to the development of TEVAR complications. The group with TEVAR-related complications showed a 10% volume increase in the descending aorta, while the group with no TEVAR-related complications only had a 1% increase. An increase of 40 mL in the descending aorta volume at 12 months seemed to be predictive of complications, with 94% specificity and 75% sensitivity. Volumetric analysis is a promising method for monitoring DTAA remodeling after TEVAR, and it may help in the early identification of high-risk patients who may benefit from a stricter follow-up, even if further evaluations on a larger sample size are required to confirm these preliminary results.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Aortic Disease and Treatment Approaches · Aortic aneurysm repair treatments · Cardiac Valve Diseases and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Pediatric and Adult CardioThoracic and Vascular, Oncohematologic and Emergency Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy
eDIMES Lab–Laboratory of Bioengineering, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy
References (33)
Show source-provided references
1. TEVAR: Endovascular Repair of the Thoracic Aorta10.1055/s-0035-1558824 ↗
2. Transluminal placement of endovascular stent-grafts for the treatment of descending thoracic aortic aneurysms10.1056/NEJM199412293312601 ↗
3. Endovascular stenting versus open surgery for thoracic aortic disease: Systematic review and meta-analysis of perioperative results10.1016/j.jvs.2007.09.062 ↗
4. Outcomes and survival following thoracic endovascular repair in patients with aortic aneurysms limited to the descending thoracic aorta10.1186/s13019-023-02285-3 ↗
5. Authors/Task Force Members, Czerny, M., Grabenwöger, M., Berger, T., Aboyans, V., Della Corte, A., Chen, E.P., Desai, N.D., Dumfarth, J., and Elefteriades, J.A. (2024). EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ. Ann. Thorac. Surg., 118, 5–115.10.1016/j.athoracsur.2024.01.021 ↗
6. Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: A systematic review and prospective cohort study10.3310/ABUT7744 ↗
7. Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms10.1136/bmjopen-2020-043323 ↗
8. Open versus Endovascular Repair of Abdominal Aortic Aneurysm10.1056/NEJMoa1715955 ↗
9. Distal Stent Graft-Induced New Entry: An Emerging Complication of Endovascular Treatment in Aortic Dissection10.1016/j.athoracsur.2016.02.001 ↗
10. Writing Committee Members, Isselbacher, E.M., Preventza, O., Hamilton Black Iii, J., Augoustides, J.G., Beck, A.W., Bolen, M.A., Braverman, A.C., Bray, B.E., and Brown-Zimmerman, M.M. (2022). 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J. Am. Coll. Cardiol., 80, e223–e393.10.1016/j.jacc.2022.08.004 ↗
11. The Need for Standardized Methods for Measuring the Aorta: Multimodality Core Lab Experience From the GenTAC Registry10.1016/j.jcmg.2015.06.023 ↗
12. Masson, E. (2024, June 24). Biomodeling and 3D Printing: A Novel Radiology Subspecialty. In: EM-Consulte. Available online: https://www.em-consulte.com/article/1489895/biomodeling-and-3d-printing-a-novel-radiology-subs.
13. Interpreting nephrometry scores with three-dimensional virtual modelling for better planning of robotic partial nephrectomy and predicting complications10.1016/j.urolonc.2021.07.024 ↗
14. Pretreatment tumor volume and tumor sphericity as prognostic factors in patients with oral cavity squamous cell carcinoma10.1016/j.jcms.2018.12.019 ↗
15. Comparison of segmentation software packages for in-hospital 3D print workflow10.1117/1.JMI.8.3.034004 ↗
16. (2024, June 25). Krishnan Suresh Volume of a Surface Triangulation. Available online: https://it.mathworks.com/matlabcentral/fileexchange/26982-volume-of-a-surface-triangulation.
17. Endovascular treatment of thoracic aortic aneurysms: Results of the phase II multicenter trial of the GORE TAG thoracic endoprosthesis10.1016/j.jvs.2004.10.046 ↗
18. Pivotal results of the Medtronic Vascular Talent Thoracic Stent Graft System: The VALOR trial10.1016/j.jvs.2008.03.061 ↗
19. International controlled clinical trial of thoracic endovascular aneurysm repair with the Zenith TX2 endovascular graft: 1-year results10.1016/j.jvs.2007.10.032 ↗
20. Variation in maximum diameter measurements of descending thoracic aortic aneurysms using unformatted planes versus images corrected to aortic centerline10.1016/j.ejvs.2013.09.026 ↗
21. Proximal thoracic aortic diameter measurements at CT: Repeatability and reproducibility according to measurement method10.1007/s10554-012-0102-9 ↗
22. Maximal aneurysm diameter follow-up is inadequate after endovascular abdominal aortic aneurysm repair10.1053/ejvs.1999.1051 ↗
23. Changes in aneurysm volume after endovascular repair of abdominal aortic aneurysm10.1067/mva.2002.126085 ↗
24. Volume regression of abdominal aortic aneurysms and its relation to successful endoluminal exclusion10.1016/S0741-5214(03)00924-8 ↗
25. Follow-up of aortic stent grafts: Comparison of the volumetric analysis of the aneurysm sac by ultrasound and CT10.1016/j.avsg.2014.03.034 ↗
26. A systematic review of protocols for the three-dimensional morphologic assessment of abdominal aortic aneurysms using computed tomographic angiography10.1007/s00270-011-0296-6 ↗
27. Aortic remodelling after thoracic endovascular aortic repair in acute and chronic type B aortic dissections10.1093/ejcts/ezaa118 ↗
28. Volumetric analysis of type B aortic dissections treated with thoracic endovascular aortic repair10.1016/j.jvs.2011.03.263 ↗
29. Gaudry, M., Guivier-Curien, C., Blanchard, A., Porto, A., Bal, L., Omnes, V., De Masi, M., Lu, C., Jacquier, A., and Piquet, P. (2022). Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair. J. Cardiovasc. Dev. Dis., 9.10.3390/jcdd9100349 ↗
30. Comparison of Volumetric and Diametric Analysis in Endovascular Repair of Descending Thoracic Aortic Aneurysm10.1016/j.ejvs.2015.02.021 ↗
31. Distal landing zone optimization before endovascular repair of aortic dissection10.1016/j.jtcvs.2018.06.095 ↗
32. More Attention Needed for the Distal Landing Zone in TEVAR10.1016/j.ejvs.2019.03.041 ↗
33. (2024, June 24). Natural History of Descending Thoracic and Thoracoabdominal Aortic Aneurysms—PubMed. Available online: https://pubmed-ncbi-nlm-nih-gov.ezproxy.unibo.it/31982126/.