Three-Dimensional Pulp Volume Analysis in Lip and Palate Cleft Population
Source abstract
Abstract
Aim: Cleft lip and palate (CLP) patients have a greater predisposition to tooth malformation, which could affect pulp volume. The aim of this study is to evaluate the dental pulp volume of central incisors in 3D images between individuals with and without CLP. Materials and Methods: This retrospective case-control study is single-centered and was recruited between January 2016 and October 2022. Ninety-four patients who were followed in the Institute of Orthodontics were evaluated and divided into two groups: a control group of patients without CLP and a test group of patients with CLP. The 3D data were imported by 3D image semi-automatic segmenting software named ITK-SNAP to calculate tooth pulp volume. Results: The dental pulp volume for both groups, control and CLP, did not show statistically significant differences. In the cleft group, when comparing the pulp volume between the cleft side and the non-cleft side, the cleft side showed a smaller volume. Regarding age and sex, no statistically significant differences were observed. Conclusions: Although there are no differences in mean pulp volume between patients with and without CLP, there is a pulp volume reduction in the teeth on the cleft side when compared to the unaffected contralateral side.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Cleft Lip and Palate Research · dental development and anomalies · Dental Trauma and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal
Coimbra Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal
Laboratory for Evidence-Based Sciences and Precision Dentistry, University of Coimbra, 3000-075 Coimbra, Portugal
Centre for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3000-075 Coimbra, Portugal
Clinical Academic Center of Coimbra (CACC), Hospitais da Universidade de Coimbra, 3004-561 Coimbra, Portugal
Laboratory of Biostatistics and Medical Informatics (LBIM), Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal
Institute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal
Institute of Experimental Pathology, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal
References (39)
Show source-provided references
1. Age Determinations on Teeth10.14219/jada.archive.1950.0132 ↗
2. Secondary Dentine as a Sole Parameter for Age Estimation: Comparison and Reliability of Qualitative and Quantitative Methods among North Western Adult Indians10.1016/j.ejfs.2016.05.006 ↗
3. An Improved Technique Using Dental Histology for Estimation of Adult Age10.1520/JFS10735J ↗
4. A New Method for Dental Age Estimation in Adults10.1016/0379-0738(93)90152-Z ↗
5. Three-Dimensional Observation of Decrease in Pulp Cavity Volume Using Micro-CT: Age-Related Change10.2209/tdcpublication.51.1 ↗
6. Human Age Estimation from Tooth Cementum and Dentin
7. Age Estimation of Adults from Dental Radiographs10.1016/0379-0738(95)01760-G ↗
8. Age Estimation Using Maxillary Central Incisors: A Radiographic Study10.4103/0975-1475.109897 ↗
9. Age and Sex Estimation Based on Pulp Cavity Volume Using Cone Beam Computed Tomography: Development and Validation of Formulas in a Brazilian Sample10.1259/dmfr.20190053 ↗
10. Age Estimation Using the Maxillary Canine Pulp/Tooth Ratio in Korean Adults: A CBCT Buccolingual and Horizontal Section Image Analysis10.1016/j.jofri.2016.12.001 ↗
11. Age Estimation Based on Pulp Cavity/Chamber Volume of 13 Types of Tooth from Cone Beam Computed Tomography Images10.1007/s00414-016-1384-6 ↗
12. Radiocarbon Analysis of Human Remains: A Review of Forensic Applications10.1111/1556-4029.12535 ↗
13. Hillson, S. (2018). Biological Anthropology of the Human Skeleton, John Wiley & Sons, Inc.
14. Buikstra, J.E., and Ubelaker, D.H. (2012). Standards for Data Collection from Human Skeletal Remains, University of Arkansas.
15. Manini, A., Savino, G., and Calliada, F. (2020). Radiographic Anatomy, Springer.
16. Ageing of the Hypothalamo-Pituitary-Testicular Axis in Men10.1159/000184233 ↗
17. Chronological versus Dental Age in Subjects from 5 to 19 Years: A Comparative Study with Forensic Implications
18. Age Estimation in Archaeological Skeletal Remains: Evaluation of Four Non-Destructive Age Calculation Methods
19. Legal Medical Age Estimation in Portuguese Adult Cadavers: Evaluation of the Accuracy of Forensic Dental Invasive and Non-Invasive Methods
20. Age Estimation from Pulp/Tooth Area Ratio in Three Mandibular Teeth by Panoramic Radiographs: Study of an Egyptian Sample10.4172/2157-7145.1000231 ↗
21. Age Estimation Based on Pulp Chamber Volume of First Molars from Cone-Beam Computed Tomography Images10.1016/j.forsciint.2015.05.004 ↗
22. Prevalence of Dental Anomalies in Nonsyndromic Individuals with Cleft Lip and Palate: A Systematic Review and Meta-Analysis10.1597/10-043 ↗
23. Pulp Enlargement in Individuals Born with Cleft Lip and Palate Pulp, a Radiographic Study from the Cleft Lip and Palate Service of Paraiba, Brazil10.1007/s40368-021-00673-8 ↗
24. Side of Dental Anomalies and Taurodontism as Potential Clinical Markers for Cleft Subphenotypes10.1597/09-159 ↗
25. Prevalence of Dental Anomalies in a Population of Cleft Lip and Palate Patients10.1597/08-275.1 ↗
26. Treatment of Dental Anomalies in Children with Complete Unilateral Cleft Lip and Palate at Sickkids Hospital, Toronto10.1597/07-239.1 ↗
27. An Index for Measuring the Wear of Teeth10.1038/sj.bdj.4805394 ↗
28. Relationship between Pulp-Tooth Volume Ratios and Chronological Age in Different Anterior Teeth on CBCT
29. Upper Central Incisor and Canine Tooth Crown Size in 47,XXY Males10.1177/00220345910700070801 ↗
30. Sexual Dimorphism of Canine Volume: A Pilot Study10.1016/j.legalmed.2014.12.006 ↗
31. Prevalence of Dental Anomalies in Patients with Cleft Lip and Palate10.1097/SCS.0b013e3182801bc8 ↗
32. A Cross-Sectional Analysis of the Prevalence of Tooth Agenesis and Structural Dental Anomalies in Association with Cleft Type in Non-Syndromic Oral Cleft Patients10.1186/s40510-017-0169-x ↗
33. Distribution Patterns of Primary and Permanent Dentition in Children with Unilateral Complete Cleft Lip and Palate10.1597/1545-1569_1998_035_0154_dpopap_2.3.co_2 ↗
34. Dental Anomalies in Individuals with Cleft Lip and/or Palate10.1093/ejo/cjp156 ↗
35. Assessment of Pulp Volume Changes after Surgically Assisted Rapid Palatal Expansion10.1016/j.jormas.2020.06.014 ↗
36. Pulpal Response to Orthodontic Tooth Movement in Adolescents: A Radiographic Study10.1016/0889-5406(92)70091-N ↗
37. Volumetric Pulp Changes after Orthodontic Treatment Determined by Cone-Beam Computed Tomography10.1016/j.joen.2014.07.029 ↗
38. Evaluation of the Periodontal Disease Effect on Pulp Volume10.1016/j.joen.2017.09.005 ↗
39. Periodontal Disease in Patients with Cleft Palate and Patients with Unilateral and Bilateral Clefts of Lip, Palate, and Alveolus10.1902/jop.1999.70.2.171 ↗