journal article·2022-11-11Open access

Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm

Meng Sun, Tao Liu, George Barbastathis, Yincheng Qi, Fucai Zhang

Applied Sciences· Volume 12· Issue 22

Abstract

Phase contrast imaging is advantageous for mitigating radiation damage to samples, such as biological specimens. For imaging at nanometer or atomic resolution, the required flux on samples increases dramatically and can easily exceed the sample damage threshold. Coherent modulation imaging (CMI) can provide quantitative absorption and phase images of samples at diffraction-limited resolution with fast convergence. When used for radiation-sensitive samples, CMI experiments need to be conducted under low illumination flux for high resolution. Here, an algorithmic framework is proposed for CMI involving generalized alternating projection and total variation constraint. A five-to-ten-fold lower photon requirement can be achieved for near-field or far-field experiment dataset. The work would make CMI more applicable to the dynamics study of radiation-sensitive samples.
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Research context

OpenAlex topics: Advanced X-ray Imaging Techniques · Advanced Electron Microscopy Techniques and Applications · Integrated Circuits and Semiconductor Failure Analysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Hebei Key Laboratory of Power Internet of Things Technology and the Department of Electronics and Communication Engineering, North China Electric Power University, Baoding 071003, China

Shenzhen Key Laboratory of Robotics Perception and Intelligence and the Department of Electrical and Electronic Engineering, Southern University of Science and Technology, 1088 Xueyuan Avenue, Shenzhen 518055, China

Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA

Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 Create Way, Singapore 117543, Singapore

Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 Create Way, Washington, DC 20036, USA

Funding

Natural National Science Foundation of China (NSFC) · Shenzhen Key Laboratory of Robotics Perception and Intelligence · Southern University of Science and Technology; Shenzhen Science and Technology Program · Centers for Mechanical Engineering Research and Education at MIT and SUSTech (MechERE Centers at MIT and SUSTech) · S&T Program of Hebei

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