DataVXApplied SciencesPaper
journal article·2021-05-25Open access

Antimigration Effects of the Number of Flaps on a Plastic Stent: Three-Dimensionally Printed Pancreatic Phantom and Ex Vivo Studies

Dae-Sung Ryu, Joon-Myeong Choi, Woo-Jin Kim, Jeon-Min Kang, Ki-Baek Lee, Yu-Been Park, Dong-Sung Won, Ji-Won Kim, Song-Hee Kim, Pyeong-Hwa Kim, Song-Cheol Kim, Jung-Hoon Park

Applied Sciences· Volume 11· Issue 11
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Source abstract

Abstract

Stent migration is a significant obstacle to successful stent placement. There has been no investigation of the effect and quantitative interpretation of flaps attached to a plastic stent (PS) on antimigration. The antimigration effects of the number of flaps on a PS in a 3D-printed pancreatic phantom (3DP) and extracted porcine pancreas (EPP) were investigated. Four PS types were used in this study: stent without flaps (type 1), stent with two flaps (type 2), stent with four horizontally made flaps (type 3), and stent with four vertically made flaps (type 4). The stents were measured and compared for antimigration force (AMF) in the 3DP and EPP using a customized measuring method and an integrated measuring device. The mean maximum AMFs (MAMFs) in types 2, 3, and 4 were significantly higher than that in type 1 (all p < 0.001). Moreover, the mean MAMFs in types 3 and 4 were significantly higher than that in type 2 (all p < 0.001). When the flaps were removed from the pancreatic duct, the AMF decreased rapidly. As the number of flaps increased, the antimigration effects significantly increased in the 3DP and EPP. However, the direction of the flaps did not affect the MAMF. The position of the flaps attached to the surface of the stent affected the AMF.
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Research context

OpenAlex topics: Gallbladder and Bile Duct Disorders · Pancreatic and Hepatic Oncology Research · Anatomy and Medical Technology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Biomedical Engineering Research Center, Asan Institute for Life Sciences, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea

Department of Convergence Medicine, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea

Safety System R&D Group, Korea Institute of Industrial Technology, 320 Techno-sunhwan-ro, Yuga-myeon, Dalseong-gun, Daegu 42994, Korea

Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea

Division of Hepatobiliary Pancreas Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea

Asan Medical Institute of Convergence Science and Technology (AMIST), Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea

Funding

KITECH R&D program · Korea Medical Device Development Fund grand funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, Republic of Korea, the Ministry of Food and Drug Safety)

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