Double Properties of Novel Acylhydrazone Nanomaterials Based on a Conjugated System: Anion Binding Ability and Antibacterial Activity
Source abstract
Abstract
A series of new compounds (1–12) containing 1,5-diaza-fluorenone, 1,10-phenanthroline-5,6-dione, ferrocene-1,1ʹ-dione, anthracene-9-carbaldehyde have been synthesized and optimized. The nanomaterials were also developed successfully. The binding properties were evaluated for biologically important anions (F−, Cl−, Br−, I−, AcO−, and H2PO4−) by theoretical investigation, UV-vis, and fluorescence experiments, and compound 6 displayed the strongest binding ability for AcO− ion among the synthesized compounds. Theoretical investigation analysis revealed that the intramolecular hydrogen bond existed in the structure of compound 6 and the roles of molecular frontier orbitals in molecular interplay. In addition, compound 6 showed wide antibacterial activity for colon bacillus, typhoid bacillus, and Pseudomonas aeruginosa, and inferior activity for hay bacillus and Staphylococcus aureus. This series of acylhydrazone nanomaterials showed double properties, anion binding ability, and antibacterial activity.
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Research context
OpenAlex topics: Molecular Sensors and Ion Detection · Metal complexes synthesis and properties · Synthesis and Characterization of Heterocyclic Compounds
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, Xinxiang Medical University, Xinxiang 453003, Henan, China
Department of Immunity, Xinxiang Medical University, Xinxiang 453003, Henan, China
School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, Henan, China
Department of Chemistry, Nankai University, Tianjin 300071, China
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