journal article·2021-10-15Open access

Research Advances and Application Prospect of Low-Temperature Plasma in Tumor Immunotherapy

Xiangni Wang, Xingmin Shi, Guanjun Zhang

Applied Sciences· Volume 11· Issue 20

Abstract

As an emerging technology, low-temperature plasma (LTP) is widely used in medical fields such as sterilization, wound healing, stomatology, and cancer treatment. Great achievements have been made in tumor therapy. In vitro and in vivo studies have shown that LTP has anti-tumor effects, and LTP is selective to tumor cells. Studies in recent years have found that LTP can activate dendritic cells (DC), macrophages, T cells, and other immune cells to achieve anti-tumor effects. This paper reviews the current status of tumor immunotherapy, the application of LTP in antitumor therapy, the activation of antitumor immunity by LTP, the possible mechanism of LTP in antitumor immunity, and meanwhile analyses the prospect of applying LTP in tumor immunotherapy.
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Research context

OpenAlex topics: Plasma Applications and Diagnostics · Nanoplatforms for cancer theranostics · CAR-T cell therapy research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Public Health, Xi’an Jiaotong University, Xi’an 710061, China

Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Xi’an 710061, China

School of Electrical Engineering, Xi’an Jiaotong University, Xi’an 710049, China

Funding

the General Program of National Natural Science

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