journal article·2022-07-22Open access

A Cascade Model with Prior Knowledge for Bone Age Assessment

Nanxin Li, Bochao Cheng, Junran Zhang

Applied Sciences· Volume 12· Issue 15

Abstract

Bone age is commonly used to reflect growth and development trends in children, predict adult heights, and diagnose endocrine disorders. Nevertheless, the existing automated bone age assessment (BAA) models do not consider the nonlinearity and continuity of hand bone development simultaneously. In addition, most existing BAA models are based on datasets from European and American children and may not be applicable to the developmental characteristics of Chinese children. Thus, this work proposes a cascade model that fuses prior knowledge. Specifically, a novel bone age representation is defined, which incorporates nonlinear and continuous features of skeletal development and is implemented by a cascade model. Moreover, corresponding regions of interest (RoIs) based on RUS-CHN were extracted by YOLO v5 as prior knowledge inputs to the model. In addition, based on MobileNet v2, an improved feature extractor was proposed by introducing the Convolutional Block Attention Module and increasing the receptive field to improve the accuracy of the evaluation. The experimental results show that the mean absolute error (MAE) is 4.44 months and significant correlations with the reference bone age is (r = 0.994, p < 0.01); accuracy is 94.04% for ground truth within ±1 year. Overall, the model design adequately considers hand bone development features and has high accuracy and consistency, and it also has some applicability on public datasets, showing potential for practical and clinical applications.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Human Pose and Action Recognition · Forensic Anthropology and Bioarchaeology Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Electrical Engineering, Sichuan University, Chengdu 610065, China

West China Second University Hospital, Sichuan University, Chengdu 610041, China

Funding

Sichuan Science and Technology Program · Chengdu Science and Technology Program · Smart Grid Sichuan Provincial Key Laboratory Emergency Key Project

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