journal article·2021-01-25Open access

Coronally Advanced Flap in the Treatment of Multiple Adjacent Gingival Recessions along with a Connective Tissue Graft Harvested from Augmented or Nonaugmented Palatal Mucous Membrane: A Two-Year Comparative Clinical Evaluation

Wojciech Bednarz, Jennifer Majer, Justyna Pakuszyńska-Błaszczyk, Marzena Dominiak, Tomasz Gedrange, Agata Zielińska-Pałasz

Applied Sciences· Volume 11· Issue 3

Abstract

Achieving the coverage of multiple adjacent gingival recessions (MAGRs) in a single surgical procedure poses a major clinical challenge. The gold standard procedure involves the collection of autogenous connective tissue from the palatal mucosa. In case of reduced palatal tissue thickness, augmentation using a collagen sponge can be performed. The aim of this study was to compare the treatment outcome of MAGR coverage by a coronally advanced flap (CAF) along with a connective tissue graft (CTG) harvested from augmented or nonaugmented palatal mucous membrane. Thirty-five patients with 148 MAGRs were enrolled in the study. The recessions were covered with CTGs collected from 26 augmented- (test group) and from 24 nonaugmented (control group) palatal donor sites followed by a CAF. Clinical parameters were measured at baseline, 6, 12 and 24 months after intervention. Clinical results for both, the test and the control group were steady and similar with the exception of buccal gingival thickness (BGT1). After 24 months, statistically greater BGT1 and complete root coverage (CRC) was observed in the test group. The augmented CTG+CAF method achieves good and predictable clinical results in the coverage of MAGRs. It leads to the increase of gingival thickness in comparison to the nonaugmented intervention.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Periodontal Regeneration and Treatments · Oral and gingival health research · Oral and Maxillofacial Pathology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Specialist Outpatient Medical Clinic MEDIDENT, Okulickiego 19 str., PL 38-300 Gorlice, Poland

Department of Periodontology, Medical University in Wroclaw, Krakowska 26 str., PL 50-425 Wroclaw, Poland

Department of Orthodontics, Carl Gustav Carus Campus, Technische Universität Dresden, Fetscherstr. 74, D-01309 Dresden, Germany

Department of Dental Surgery, Medical University in Wroclaw, Krakowska 26 str., PL 50-425 Wroclaw, Poland

References (53)

Show source-provided references
1. Mucogingival deformities
2. New perspectives in the diagnostic of gingival recession10.17219/acem/27907 ↗
3. Treatment of multiple recession-type defects in patients with esthetic demands10.1902/jop.2000.71.9.1506 ↗
4. Long-Term Results Comparing Xenogeneic Collagen Matrix and Autogenous Connective Tissue Grafts with Coronally Advanced Flaps for Treatment of Dehiscence-Type Recession Defects10.1902/jop.2015.150386 ↗
5. Long-Term Stability of Root Coverage by Coronally Advanced Flap Procedures10.1902/jop.2017.160767 ↗
6. Root coverage procedures for treating single and multiple recession-type defects: An updated Cochrane systematic review10.1002/JPER.19-0079 ↗
7. Human Palatal and Tuberosity Mucosa as Donor Sites for Ridge Augmentation10.11607/prd.1929 ↗
8. Palatal wound healing using a xenogeneic collagen matrix–histological outcomes of a randomized controlled clinical trial10.1111/jcpe.12624 ↗
9. Vascularization and Innervation of Connective Tissue Grafts in the Treatment of Gingival Recessions: A Histologic and Immunohistochemical Study10.11607/prd.3020 ↗
10. Histology of connective tissue graft. A case report10.1902/jop.2001.72.11.1607 ↗
11. Histologic evaluation of connective tissue grafts in humans
12. Ultrastructural changes in human gingival fibroblasts in vitro after exposure to vapour phase smoke components10.1016/S0940-9602(00)80048-5 ↗
13. Clinical measurements of hard palate and implications for subepithelial connective tissue grafts with suggestions for palatal nomenclature10.1016/j.joms.2011.03.066 ↗
14. Epithelial inclusions following a bilaminar root coverage procedure with a subepithelial connective tissue graft: A histologic and clinical study10.11607/prd.3189 ↗
15. A technique for augmenting the palatal connective tissue donor site: Clinical case report and histologic evaluation
16. Augmentation of the hard palate thin masticatory mucosa in the potential connective tissue donor sites using two collagen materials–clinical and histological comparison10.1016/j.aanat.2016.02.008 ↗
17. Root coverage with a connective tissue with partial thickness double pedicle graft an acellular dermal matrix graft: A clinical and histological evaluation of a case report10.1902/jop.1998.69.11.1305 ↗
18. Predictable multiple site root coverage using an acellular dermal matrix allograft10.1902/jop.2001.72.5.571 ↗
19. Clinical evaluation of a new collagen matrix (Mucograft prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: A randomized prospective clinical trial10.1111/j.1600-051X.2009.01460.x ↗
20. Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: Randomized trial assessing non-inferiority in root coverage and superiority in oral health-related10.1111/jcpe.12834 ↗
21. Biodegradation pattern and tissue integration and cross-linked porcine collagen soft tissue augmentation matrices–an experimental study in rat10.1186/1746-160X-10-10 ↗
22. The Feasability of using coronally advanced flap with an extracellular matrix membrane for treating gingival recession defects. A preclinical study10.11607/prd.2069 ↗
23. Comparative research concerning clinical efficiency of three surgical methods of periodontium recessions treatment in five-year observations
24. Xenogeneic collagen matrix with coronally advanced flap compared to connective tissue with coronally advanced flap for the treatment of dehiscence-type recession defects10.1902/jop.2010.090698 ↗
25. Use of Platelet-Rich Fibrin Membrane in the Treatment of Gingival Recession: A Systematic Review and Meta-Analysis10.1902/jop.2015.150420 ↗
26. A classification of marginal tissue recession
27. Ultrasonic Biometer and its usage in an assessment of periodontal soft tissue thickness and comparison of its measurement accuracy with a bone sounding method
28. Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: A randomized-controlled clinical trial10.1111/j.1600-051X.2010.01550.x ↗
29. The partly epithelialized free gingival graft (pe-fgg) at lower incisors. A pilot study with implications for alignment of the muco-gingival junction10.1111/j.1600-051X.2012.01896.x ↗
30. Treatment of class III multiple gingival recessions: Prognostic factors for achieving a complete root coverage10.1111/jcpe.12923 ↗
31. Long term assessment of root coverage stability using connective tissue graft with or without an epithelial collar for gingival recession treatment. A 12-year follow-up from a randomized clinical trial10.1111/jcpe.13187 ↗
32. Concentrated growth factor in the treatment of adjacent multiple gingival recessions: A split-mouth randomized clinical trial10.1111/jcpe.12444 ↗
33. Efficacy of periodontal plastic procedures in the treatment of multiple gingival recessions10.1111/jcpe.12172 ↗
34. Coronally advanced flap with and without connective tissue graft for the treatment of multiple gingival recessions: A comparative short- and long-term controlled randomized clinical trial10.1111/jcpe.12224 ↗
35. Predictor factors for long-term outcomes stability of coronally advanced flap with or without connective tissue graft in the treatment of single maxillary gingival recessions: 9 years results of a randomized controlled clinical trial10.1111/jcpe.12932 ↗
36. Clinical insights about the evolution of root coverage procedures: The flap, the graft, and the surgery10.1002/JPER.18-0281 ↗
37. Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft10.1902/jop.2004.75.3.413 ↗
38. Clinical efficacy of coronally advanced flap with or without connective tissue graft for the treatment of multiple adjacent gingival recessions in the aesthetic area: A randomized controlled clinical trial10.1111/jcpe.12590 ↗
39. Coronal advanced flap in combination with a connective tissue graft. Is the thickness of the flap a predictor for root coverage? A prospective clinical study10.1111/jcpe.12769 ↗
40. Clinical evaluation of Miller class I and II recessions treatment with the use of modified coronally advanced tunnel technique with either collagen matrix or subepithelial connective tissue graft: A randomized clinical study10.1111/jcpe.13031 ↗
41. Long-term outcome following treatment of multiple Miller class I and II recession defects in esthetic areas of the mouth10.1902/jop.2005.76.12.2286 ↗
42. Coronally advanced flap versus connective tissue graft in the treatment of multiple gingival recessions: A split-mouth study with a 5-year follow-up10.1111/j.1600-051X.2010.01559.x ↗
43. Is a soft tissue graft harvested from the maxillary tuberosity the approach of choice in an isolated site?10.1002/JPER.18-0615 ↗
44. Biologically guided flap stability: The role of flap thickness including periosteum retention on the performance of the coronally advanced flap–A double- blind randomized clinical trial10.1111/jcpe.12998 ↗
45. Split-mouth comparison of a coronally advanced flap with or without enamel matrix derivative for coverage of multiple gingival recession defects: 6- and 24-month follow-up
46. Comparison of the clinical outcomes of connective tissue and acellular dermal matrix in combination with double papillary flap for root coverage: A 6 month trial
47. Acellular dermal matrix and coronally advanced flap or tunnel technique in the treatment of multiple adjacent gingival recessions. A 12-year follow-up from a randomized clinical trial10.1111/jcpe.13163 ↗
48. Factors affecting the outcomes of coronally advanced flap root coverage procedure10.1902/jop.2005.76.10.1729 ↗
49. Flap thickness as a predictor of root coverage: A systematic review10.1902/jop.2006.060107 ↗
50. Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivative for root coverage: A RCT using 3D digital measuring methods. Part II. Volumetric studies on healing dynamics and gingival dimensions10.1111/jcpe.12254 ↗
51. Palatal Augmentation Technique. A Predictable Method to Increase the Palatal Connective Tissue Donor Site: A Consecutive Case Series10.11607/prd.2090 ↗
52. Influence of tooth location on coronally advanced flap procedures for root coverage10.1002/JPER.18-0201 ↗
53. The influence of tooth location on the outcomes of multiple adjacent gingival recessions treated with coronally advanced flap: A multicenter re-analysis study10.1002/JPER.18-0732 ↗